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Literature DB >> 32061307

Diagnostic Power of DNA Methylation Classifiers for Early Detection of Cancer.

Abstract

DNA methylation-based epigenetic signatures have become valuable cancer biomarkers. We highlight the advantages of liquid biopsy based DNA-methylation profiling for noninvasive diagnosis of early stage cancers and discuss the advanced analytical approaches developed by commercial and academic partnerships.

Entities: CellLine Chemical Disease Gene Species

Keywords: DNA methylation; cancer biomarkers, epigenetics; cell-free DNA; early detection; liquid biopsy

Mesh：

Substances：

Year: 2020 PMID： 32061307 PMCID： PMC7188195 DOI： 10.1016/j.trecan.2019.12.006

Source DB: PubMed Journal: Trends Cancer ISSN： 2405-8025

15 in total

Review 1. The power and the promise of DNA methylation markers.

Authors: Peter W Laird
Journal: Nat Rev Cancer Date: 2003-04 Impact factor: 60.716

2. Sensitive tumour detection and classification using plasma cell-free DNA methylomes.

Authors: Shu Yi Shen; Rajat Singhania; Gordon Fehringer; Ankur Chakravarthy; Michael H A Roehrl; Dianne Chadwick; Philip C Zuzarte; Ayelet Borgida; Ting Ting Wang; Tiantian Li; Olena Kis; Zhen Zhao; Anna Spreafico; Tiago da Silva Medina; Yadon Wang; David Roulois; Ilias Ettayebi; Zhuo Chen; Signy Chow; Tracy Murphy; Andrea Arruda; Grainne M O'Kane; Jessica Liu; Mark Mansour; John D McPherson; Catherine O'Brien; Natasha Leighl; Philippe L Bedard; Neil Fleshner; Geoffrey Liu; Mark D Minden; Steven Gallinger; Anna Goldenberg; Trevor J Pugh; Michael M Hoffman; Scott V Bratman; Rayjean J Hung; Daniel D De Carvalho
Journal: Nature Date: 2018-11-14 Impact factor: 49.962

Review 3. Liquid biopsies come of age: towards implementation of circulating tumour DNA.

Authors: Jonathan C M Wan; Charles Massie; Javier Garcia-Corbacho; Florent Mouliere; James D Brenton; Carlos Caldas; Simon Pacey; Richard Baird; Nitzan Rosenfeld
Journal: Nat Rev Cancer Date: 2017-02-24 Impact factor: 60.716

Review 4. Epigenetic therapy in immune-oncology.

Authors: Peter A Jones; Hitoshi Ohtani; Ankur Chakravarthy; Daniel D De Carvalho
Journal: Nat Rev Cancer Date: 2019-03 Impact factor: 60.716

5. DNA methylation in circulating tumour DNA as a biomarker for cancer.

Authors: Ruth E Board; Lucy Knight; Alastair Greystoke; Fiona H Blackhall; Andrew Hughes; Caroline Dive; Malcolm Ranson
Journal: Biomark Insights Date: 2008-01-25

6. CancerDetector: ultrasensitive and non-invasive cancer detection at the resolution of individual reads using cell-free DNA methylation sequencing data.

Authors: Wenyuan Li; Qingjiao Li; Shuli Kang; Mary Same; Yonggang Zhou; Carol Sun; Chun-Chi Liu; Lea Matsuoka; Linda Sher; Wing Hung Wong; Frank Alber; Xianghong Jasmine Zhou
Journal: Nucleic Acids Res Date: 2018-09-06 Impact factor: 16.971

7. Measurement of circulating cell-free DNA in relation to 18F-fluorocholine PET/CT imaging in chemotherapy-treated advanced prostate cancer.

Authors: Sandi Kwee; Min-Ae Song; Iona Cheng; Lenora Loo; Maarit Tiirikainen
Journal: Clin Transl Sci Date: 2012-02-23 Impact factor: 4.689

8. CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNA.

Authors: Shuli Kang; Qingjiao Li; Quan Chen; Yonggang Zhou; Stacy Park; Gina Lee; Brandon Grimes; Kostyantyn Krysan; Min Yu; Wei Wang; Frank Alber; Fengzhu Sun; Steven M Dubinett; Wenyuan Li; Xianghong Jasmine Zhou
Journal: Genome Biol Date: 2017-03-24 Impact factor: 13.583

9. Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA.

Authors: Shicheng Guo; Dinh Diep; Nongluk Plongthongkum; Ho-Lim Fung; Kang Zhang; Kun Zhang
Journal: Nat Genet Date: 2017-03-06 Impact factor: 38.330

10. Monitoring of circulating tumor DNA and its aberrant methylation in the surveillance of surgical lung Cancer patients: protocol for a prospective observational study.

Authors: Guannan Kang; Kezhong Chen; Fan Yang; Shannon Chuai; Heng Zhao; Kai Zhang; Bingsi Li; Zhihong Zhang; Jun Wang
Journal: BMC Cancer Date: 2019-06-13 Impact factor: 4.430

16 in total

Diagnostic Power of DNA Methylation Classifiers for Early Detection of Cancer.

Review 1. The power and the promise of DNA methylation markers.

2. Sensitive tumour detection and classification using plasma cell-free DNA methylomes.

Review 3. Liquid biopsies come of age: towards implementation of circulating tumour DNA.

Review 4. Epigenetic therapy in immune-oncology.

5. DNA methylation in circulating tumour DNA as a biomarker for cancer.

6. CancerDetector: ultrasensitive and non-invasive cancer detection at the resolution of individual reads using cell-free DNA methylation sequencing data.

7. Measurement of circulating cell-free DNA in relation to 18F-fluorocholine PET/CT imaging in chemotherapy-treated advanced prostate cancer.

8. CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNA.

9. Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA.

10. Monitoring of circulating tumor DNA and its aberrant methylation in the surveillance of surgical lung Cancer patients: protocol for a prospective observational study.

1. Dynamic Changes of Fetal-Derived Hypermethylated RASSF1A and Septin 9 Sequences in Maternal Plasma.

Review 2. DNA methylation-based predictors of health: applications and statistical considerations.

3. Photonic technologies for liquid biopsies: recent advances and open research challenges.

4. Tumor DNA Methylation Profiles Enable Diagnosis, Prognosis Prediction, and Screening for Cervical Cancer.

5. Epigenetics and ADHD: Reflections on Current Knowledge, Research Priorities and Translational Potential.

6. The Diagnostic Potential of SHOX2 and RASSF1A DNA Methylation in Early Lung Adenocarcinoma.

7. A 3-DNA methylation signature as a novel prognostic biomarker in patients with sarcoma by bioinformatics analysis.

Review 8. Liquid Biopsies: Applications for Cancer Diagnosis and Monitoring.

Review 9. Human Papillomavirus and Cellular Pathways: Hits and Targets.

Review 10. The Potential of Aptamer-Mediated Liquid Biopsy for Early Detection of Cancer.