Literature DB >> 12671664

The power and the promise of DNA methylation markers.

Peter W Laird1.   

Abstract

The past few years have seen an explosion of interest in the epigenetics of cancer. This has been a consequence of both the exciting coalescence of the chromatin and DNA methylation fields, and the realization that DNA methylation changes are involved in human malignancies. The ubiquity of DNA methylation changes has opened the way to a host of innovative diagnostic and therapeutic strategies. Recent advances attest to the great promise of DNA methylation markers as powerful future tools in the clinic.

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Year:  2003        PMID： 12671664     DOI： 10.1038/nrc1045

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  494 in total

1.  Measurement of genome-wide DNA methylation predicts survival benefits from chemotherapy in non-small cell lung cancer.

Authors:  Min-Li Mo; Jie Ma; Zhao Chen; Bing Wei; Hui Li; Yong Zhou; Huaiyin Shi; Bhairavi Tolani; Joy Q Jin; Hsin-Hui Tseng; Dong Shen; Yi Zhan; Jun Li; David M Jablons; Rong-Qing Zhang; Yongjun Guo; Biao He; Hai-Meng Zhou
Journal:  J Cancer Res Clin Oncol       Date:  2014-11-04       Impact factor: 4.553

2.  Hypermethylation of Sox17 gene is useful as a molecular diagnostic application in early gastric cancer.

Authors:  Yoshichika Oishi; Yoshiyuki Watanabe; Yoshihito Yoshida; Yoshinori Sato; Tetsuya Hiraishi; Ritsuko Oikawa; Tadateru Maehata; Hiromu Suzuki; Minoru Toyota; Hirohumi Niwa; Michihiro Suzuki; Fumio Itoh
Journal:  Tumour Biol       Date:  2011-12-08

3.  Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis.

Authors:  Liangjing Wang; Shujie Chen; Meng Xue; Jing Zhong; Xian Wang; Lihong Gan; Emily K Y Lam; Xin Liu; Jianbin Zhang; Tianhua Zhou; Jun Yu; Hongchuan Jin; Jianmin Si
Journal:  Mol Med       Date:  2012-05-09       Impact factor: 6.354

4.  DNA methylation biomarkers for lung cancer.

Authors:  Tibor A Rauch; Zunde Wang; Xiwei Wu; Kemp H Kernstine; Arthur D Riggs; Gerd P Pfeifer
Journal:  Tumour Biol       Date:  2011-12-06

Review 5.  Statistical approaches for the analysis of DNA methylation microarray data.

Authors:  Kimberly D Siegmund
Journal:  Hum Genet       Date:  2011-04-26       Impact factor: 4.132

6.  A DNA microarray-based methylation-sensitive (MS)-AFLP hybridization method for genetic and epigenetic analyses.

Authors:  F Yamamoto; M Yamamoto
Journal:  Mol Genet Genomics       Date:  2004-05-14       Impact factor: 3.291

7.  High quality assessment of DNA methylation in archival tissues from colorectal cancer patients using quantitative high-resolution melting analysis.

Authors:  Marija Balic; Martin Pichler; Jasmin Strutz; Ellen Heitzer; Christoph Ausch; Hellmut Samonigg; Richard J Cote; Nadia Dandachi
Journal:  J Mol Diagn       Date:  2009-01-29       Impact factor: 5.568

8.  SPARSE INTEGRATIVE CLUSTERING OF MULTIPLE OMICS DATA SETS.

Authors:  Ronglai Shen; Sijian Wang; Qianxing Mo
Journal:  Ann Appl Stat       Date:  2013-04-09       Impact factor: 2.083

Review 9.  Beyond genetics--the emerging role of epigenetic changes in hematopoietic malignancies.

Authors:  Oliver Galm; Manel Esteller
Journal:  Int J Hematol       Date:  2004-08       Impact factor: 2.490

10.  DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells.

Authors:  Jon M McGough; Dafeng Yang; Shuang Huang; David Georgi; Stephen M Hewitt; Christoph Röcken; Marc Tänzer; Matthias P A Ebert; Kebin Liu
Journal:  Mol Cancer Res       Date:  2008-12       Impact factor: 5.852
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