Philipp Dietrich1, Alica Gravius2, Ruben Mühl-Benninghaus2, Umut Yilmaz2, Michael Kettner2, Hagen Bomberg3, Wolfgang Reith2, Andreas Simgen2. 1. Department of Neuroradiology, Universitätsklinikum des Saarlandes, Medizinische Fakultät, Universität des Saarlandes, Kirrbergerstraße, 66421, Homburg/Saar, Germany. philipp.dietrich1@gmx.de. 2. Department of Neuroradiology, Universitätsklinikum des Saarlandes, Medizinische Fakultät, Universität des Saarlandes, Kirrbergerstraße, 66421, Homburg/Saar, Germany. 3. Department of Anaesthesiology, Universitätsklinikum des Saarlandes und Medizinische Fakultät, Universität des Saarlandes, Homburg/Saar, Germany.
Abstract
PURPOSE: The introduction of low-profile stent systems has broadened and facilitated the treatment of complex intracranial aneurysms. This retrospective case series study was conducted to assess and compare the clinical and angiographic outcomes of patients with complex intracranial aneurysms who were treated with ACCLINO® (AS) and ACCLINO® flex stents (AFS). METHODS: In 85 patients (female 61; male 24) a total of 95 complex intracranial aneurysms, 71 (74.7%) in the anterior circulation and 24 (25.3%) in the posterior circulation were treated. Angiographic and clinical data, aneurysm characteristics and follow-up results were analyzed. RESULTS: The AS was used in 47 cases (49.5%) and the AFS in 48 cases (50.5%). Initial angiography after the intervention showed a complete occlusion in 52.6% (Raymond-Roy occlusion classification [RROC] 1), a neck remnant in 38.9% (RROC 2) and an incomplete occlusion in 8.4% (RROC 3). Follow-up (AS: 25.2 ± 15.4 months; AFS: 9.6 ± 8.0 months) revealed an occlusion rate of 70.5% (RROC 1), 27.4% (RROC 2) and 2.1% (RROC 3). There was no statistically significant difference between the initial (p = 0.484) and the follow-up occlusion rate (p = 0.284) when comparing the two devices. Recoiling was performed in 8 cases (8.4%). The overall complication rate was 9.5% with 5 strokes (5.3%), 2 hemorrhages (2.1%), 1 in-stent stenosis (1.1%), 1 stent occlusion (1.1%) and 2 stent thromboses (2.1%). There was no procedure-related mortality. CONCLUSION: Using the ACCLINO® and ACCLINO® flex stent system is a feasible and effective procedure with an acceptable safety profile. Initial and follow-up angiographic results were satisfactory.
PURPOSE: The introduction of low-profile stent systems has broadened and facilitated the treatment of complex intracranial aneurysms. This retrospective case series study was conducted to assess and compare the clinical and angiographic outcomes of patients with complex intracranial aneurysms who were treated with ACCLINO® (AS) and ACCLINO® flex stents (AFS). METHODS: In 85 patients (female 61; male 24) a total of 95 complex intracranial aneurysms, 71 (74.7%) in the anterior circulation and 24 (25.3%) in the posterior circulation were treated. Angiographic and clinical data, aneurysm characteristics and follow-up results were analyzed. RESULTS: The AS was used in 47 cases (49.5%) and the AFS in 48 cases (50.5%). Initial angiography after the intervention showed a complete occlusion in 52.6% (Raymond-Roy occlusion classification [RROC] 1), a neck remnant in 38.9% (RROC 2) and an incomplete occlusion in 8.4% (RROC 3). Follow-up (AS: 25.2 ± 15.4 months; AFS: 9.6 ± 8.0 months) revealed an occlusion rate of 70.5% (RROC 1), 27.4% (RROC 2) and 2.1% (RROC 3). There was no statistically significant difference between the initial (p = 0.484) and the follow-up occlusion rate (p = 0.284) when comparing the two devices. Recoiling was performed in 8 cases (8.4%). The overall complication rate was 9.5% with 5 strokes (5.3%), 2 hemorrhages (2.1%), 1 in-stent stenosis (1.1%), 1 stent occlusion (1.1%) and 2 stent thromboses (2.1%). There was no procedure-related mortality. CONCLUSION: Using the ACCLINO® and ACCLINO® flex stent system is a feasible and effective procedure with an acceptable safety profile. Initial and follow-up angiographic results were satisfactory.
Authors: Lukas Goertz; Michael A Smyk; Anastasios Mpotsaris; Jan Borggrefe; Franziska Dorn; Thomas Liebig; Marc Schlamann; Kai Laukamp; Boris Krischek; Bernd Turowski; Christoph Kabbasch Journal: Clin Neuroradiol Date: 2019-11-15 Impact factor: 3.649
Authors: D F Vollherbst; A Berlis; C Maurer; L Behrens; S Sirakov; A Sirakov; S Fischer; V Maus; M Holtmannspötter; R Rautio; M Sinisalo; W Poncyljusz; H Janssen; F Wodarg; C Kabbasch; J Trenkler; C Herweh; M Bendszus; M A Möhlenbruch Journal: AJNR Am J Neuroradiol Date: 2020-12-10 Impact factor: 3.825