Lukas Goertz1,2, Michael A Smyk3, Anastasios Mpotsaris4, Jan Borggrefe5, Franziska Dorn6, Thomas Liebig6, Marc Schlamann5, Kai Laukamp5, Boris Krischek7, Bernd Turowski3, Christoph Kabbasch5. 1. Department of Neuroradiology, University Hospital of Cologne, Kerpener Straße 67, 50937, Cologne, Germany. lukas.goertz@uk-koeln.de. 2. Faculty of Medicine and University Hospital, Center for Neurosurgery, University of Cologne, Kerpener Straße 67, 50937, Cologne, Germany. lukas.goertz@uk-koeln.de. 3. Department of Neuroradiology, University Hospital of Duesseldorf, Moorenstraße 5, 40225, Duesseldorf, Germany. 4. Department of Neuroradiology, University Hospital of Aachen, Pauwelsstrase 30, 52074, Aachen, Germany. 5. Department of Neuroradiology, University Hospital of Cologne, Kerpener Straße 67, 50937, Cologne, Germany. 6. Department of Neuroradiology, LMU University Hospital of Munich, Marchioninistraße 15, 81377, Munich, Germany. 7. Faculty of Medicine and University Hospital, Center for Neurosurgery, University of Cologne, Kerpener Straße 67, 50937, Cologne, Germany.
Abstract
PURPOSE: The low-profile Acandis Acclino is a self-expandable nitinol microstent for stent-assisted coiling of intracranial aneurysms. This article reports long-term clinical and angiographic outcome in a multicenter setting. METHODS: In this study 98 consecutive patients (mean age 55.4 ± 13.5 years) were treated with the Acclino for 98 aneurysms (28 unruptured, 20 recurrent, 50 ruptured) at 3 German tertiary care centers within a 6-year period. The technical success, complications, clinical outcome and angiographic results were retrospectively analyzed. RESULTS: The technical success rate was 100% with immediate complete occlusion achieved in 89.8% of the patients. Among 65 patients (66.3%) available for a 6‑month follow-up, complete and near-complete occlusion rates were 92.3% and 98.5%, respectively. In 38 patients (38.8%) with long-term follow-up (mean: 21 months), complete and near-complete occlusion were achieved in 81.2% and 89.5%, respectively. Aneurysm recurrence between mid-term and long-term follow-up was observed in 14.3%. The retreatment rate was 11.3%. There were three thromboembolic events (3.1%), of which one resulted in ischemic stroke (1.0%). For unruptured aneurysms, the procedural and device-related morbidity rates were 2.1% and 0%, respectively. CONCLUSION: In the present study, the Acclino was associated with a low risk of thromboembolic complications and high aneurysm occlusion rates at long-term follow-up. Due to incomplete angiographic follow-up in this series, prospective studies will be necessary to confirm the results.
PURPOSE: The low-profile Acandis Acclino is a self-expandable nitinol microstent for stent-assisted coiling of intracranial aneurysms. This article reports long-term clinical and angiographic outcome in a multicenter setting. METHODS: In this study 98 consecutive patients (mean age 55.4 ± 13.5 years) were treated with the Acclino for 98 aneurysms (28 unruptured, 20 recurrent, 50 ruptured) at 3 German tertiary care centers within a 6-year period. The technical success, complications, clinical outcome and angiographic results were retrospectively analyzed. RESULTS: The technical success rate was 100% with immediate complete occlusion achieved in 89.8% of the patients. Among 65 patients (66.3%) available for a 6‑month follow-up, complete and near-complete occlusion rates were 92.3% and 98.5%, respectively. In 38 patients (38.8%) with long-term follow-up (mean: 21 months), complete and near-complete occlusion were achieved in 81.2% and 89.5%, respectively. Aneurysm recurrence between mid-term and long-term follow-up was observed in 14.3%. The retreatment rate was 11.3%. There were three thromboembolic events (3.1%), of which one resulted in ischemic stroke (1.0%). For unruptured aneurysms, the procedural and device-related morbidity rates were 2.1% and 0%, respectively. CONCLUSION: In the present study, the Acclino was associated with a low risk of thromboembolic complications and high aneurysm occlusion rates at long-term follow-up. Due to incomplete angiographic follow-up in this series, prospective studies will be necessary to confirm the results.
Authors: Lukas Goertz; Michael Artur Smyk; Eberhard Siebert; Bernd Turowski; Jan Borggrefe; Anastasios Mpotsaris; Georg Bohner; Marc Schlamann; Franziska Dorn; Thomas Liebig; Christoph Kabbasch Journal: Clin Neuroradiol Date: 2020-01-22 Impact factor: 3.649
Authors: D F Vollherbst; A Berlis; C Maurer; L Behrens; S Sirakov; A Sirakov; S Fischer; V Maus; M Holtmannspötter; R Rautio; M Sinisalo; W Poncyljusz; H Janssen; F Wodarg; C Kabbasch; J Trenkler; C Herweh; M Bendszus; M A Möhlenbruch Journal: AJNR Am J Neuroradiol Date: 2020-12-10 Impact factor: 3.825