Literature DB >> 32043009

The use of demineralised bone fibres (DBF) in conjunction with supercritical carbon dioxide (SCCO2) treated allograft in anterior lumbar interbody fusion (ALIF).

Jeremy Rajadurai1,2, Vedran Lovric1,3,4, Ralph J Mobbs1,2,3,4, Wen Jie Choy1,3,4, William R Walsh1,3,4.   

Abstract

Spinal fusion is a common procedure for the treatment of various spinal pathologies. Since the early days, spinal fusion has been carried out with the use of bone grafts as interbody spacers. With the development of synthetic interbody implants, bone grafts were used to facilitate fusion. Although autograft provides the best outcomes for fusion, allografts have been sought after due to donor site morbidity and other shortcomings. Currently, a vast variety of demineralised bone matrix (DBM) products are available with their methods of processing and preparation impacting their properties and clinical outcomes. Demineralised bone fibres (DBF), a form a DBM can be easily packed into implants when mixed with other substances such as allograft bone and patient's blood providing a scaffold for the mixture. We report two cases of anterior lumbar interbody fusion (ALIF) utilising a titanium-polyetheretherketone (PEEK) interbody cage filled with DBF, allograft and patient's blood with a maximum of 12 months follow-up outcome. 2019 Journal of Spine Surgery. All rights reserved.

Entities:  

Keywords:  Demineralised bone fibres (DBF); allograft; anterior lumbar interbody fusion (ALIF); degenerative disc disease; spinal fusion

Year:  2019        PMID: 32043009      PMCID: PMC6989944          DOI: 10.21037/jss.2019.10.04

Source DB:  PubMed          Journal:  J Spine Surg        ISSN: 2414-4630


  29 in total

1.  Bone-graft substitutes: facts, fictions, and applications.

Authors:  A S Greenwald; S D Boden; V M Goldberg; Y Khan; C T Laurencin; R N Rosier
Journal:  J Bone Joint Surg Am       Date:  2001       Impact factor: 5.284

Review 2.  Overview of the biology of lumbar spine fusion and principles for selecting a bone graft substitute.

Authors:  Scott D Boden
Journal:  Spine (Phila Pa 1976)       Date:  2002-08-15       Impact factor: 3.468

3.  The effect of sterilization on the mechanical properties of intact rabbit humeri in three-point bending, four-point bending and torsion.

Authors:  Nicholas A Russell; Alain Rives; Matthew H Pelletier; Warwick J Bruce; William R Walsh
Journal:  Cell Tissue Bank       Date:  2012-05-27       Impact factor: 1.522

4.  The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: a preliminary report.

Authors:  S D Boden; T A Zdeblick; H S Sandhu; S E Heim
Journal:  Spine (Phila Pa 1976)       Date:  2000-02-01       Impact factor: 3.468

Review 5.  Bone graft substitutes for anterior lumbar interbody fusion.

Authors:  Ralph J Mobbs; Mina Chung; Prashanth J Rao
Journal:  Orthop Surg       Date:  2013-05       Impact factor: 2.071

6.  Prevalence, complications, and hospital charges associated with use of bone-morphogenetic proteins in spinal fusion procedures.

Authors:  Kevin S Cahill; John H Chi; Arthur Day; Elizabeth B Claus
Journal:  JAMA       Date:  2009-07-01       Impact factor: 56.272

7.  Comparison of posterolateral lumbar fusion rates of Grafton Putty and OP-1 Putty in an athymic rat model.

Authors:  David A Bomback; Jonathan N Grauer; Roberto Lugo; Nancy Troiano; Tushar Ch Patel; Gary E Friedlaender
Journal:  Spine (Phila Pa 1976)       Date:  2004-08-01       Impact factor: 3.468

8.  Titanium/Polyetheretherketone Cages for Cervical Arthrodesis with Degenerative and Traumatic Pathologies: Early Clinical Outcomes and Fusion Rates.

Authors:  Elizabeth Chong; Ralph J Mobbs; Matthew H Pelletier; William R Walsh
Journal:  Orthop Surg       Date:  2016-02       Impact factor: 2.071

9.  Prospective nonrandomized comparison of an allograft with bone morphogenic protein versus an iliac-crest autograft in anterior cervical discectomy and fusion.

Authors:  Glenn Robin Buttermann
Journal:  Spine J       Date:  2007-03-07       Impact factor: 4.166

Review 10.  Demineralized bone matrix in bone repair: history and use.

Authors:  Elliott Gruskin; Bruce A Doll; F William Futrell; John P Schmitz; Jeffrey O Hollinger
Journal:  Adv Drug Deliv Rev       Date:  2012-06-21       Impact factor: 15.470

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