Literature DB >> 32020239

[Testicular tumors in prepubertal boys-organ preservation possible more often than expected].

R Stein1, M Dürken2, K Zahn3, Nina Younsi3.   

Abstract

In prepubertal boystesticular tumors are rare with an incidence between 2 and 5/million. In contrast to testicular tumors in adolescents and adults, more than 2/3 of these tumors are benign. Unfortunately, in Germany in most cases, only malignant tumors (usually yolk sac tumors) are reported to the study center (MAKEI IV and now V). Therefore, the incidence in Germany is unknown. Since the introduction of polychemotherapy in the 1970s, the prognosis of malignant testicular tumors has improved enormously and has become a curable disease, even in the case of recurrence. Today the orchiectomy, which was usually carried out in the past, appears to be no longer justified in most prepubertal boys due to the high incidence of benign tumors. It has been shown in various studies that organ-sparing surgery in germ cell tumors (epidermoid cysts, teratoma); gonadal stoma tumors (Sertoli, Leydig and granulosa cell tumors) and cystic lesions (intratesticular cysts and tubular ectasia of the rete testis) is reliable and safe. In cases with preoperative significantly increased AFP (caution: norm values not valid in the first year of life) and a clear testicular tumor in the ultrasound (yolk sac tumor) or if no testicular parenchyma is sonographically detectable, orchiectomy can still be carried out. Today orchiectomies in prepubertal boys should be an exception and the reasons for an orchiectomy must be well documented.

Entities:  

Keywords:  Adolescents; Biological tumor markers; Children; Orchiectomy; Teratoma

Mesh:

Substances:

Year:  2020        PMID: 32020239     DOI: 10.1007/s00120-020-01120-0

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  52 in total

1.  Testicular and paratesticular tumors in children.

Authors:  Francisco Javier Murcia-Pascual; Raquel Gracia-Rodríguez; Fernando Vázquez-Rueda; Pedro López Pereira; Rosa María Paredes Esteban
Journal:  Arch Esp Urol       Date:  2016-12       Impact factor: 0.436

Review 2.  Diagnostic value of alpha 1-fetoprotein and beta-human chorionic gonadotropin in infancy and childhood.

Authors:  D T Schneider; G Calaminus; U Göbel
Journal:  Pediatr Hematol Oncol       Date:  2001 Jan-Feb       Impact factor: 1.969

3.  Should we rely on Doppler ultrasound for evaluation of testicular solid lesions?

Authors:  Baris Esen; Muhiddin Önder Yaman; Sümer Baltacı
Journal:  World J Urol       Date:  2018-03-23       Impact factor: 4.226

4.  Is testis-sparing surgery safe in small testicular masses? Results of a multicentre study.

Authors:  Murat Keske; Abdullah Erdem Canda; Serdar Yalcin; Aydan Kilicarslan; Yusuf Kibar; Can Tuygun; Evrim Onder; Ali Fuat Atmaca; Asif Yildirim; Sidika Seyma Ozkanli; Olcay Kandemir; Taner Kargi; Mehmet Sar; Volkan Tugcu; Berkan Resorlu; Yilmaz Aslan; Selcuk Sarikaya; Ugur Boylu; Ali Fuat Cicek; Halil Basar; Altug Tuncel; Mevlana Derya Balbay
Journal:  Can Urol Assoc J       Date:  2017-03-16       Impact factor: 1.862

5.  Improved chemotherapy in disseminated testicular cancer.

Authors:  L H Einhorn; J P Donohue
Journal:  J Urol       Date:  1977-01       Impact factor: 7.450

6.  Testis sparing surgery for Leydig cell pathologies in children.

Authors:  Senol Emre; Rahsan Ozcan; Mehmet Elicevik; Haluk Emir; Yunus Soylet; Cenk Buyukunal
Journal:  J Pediatr Urol       Date:  2016-10-11       Impact factor: 1.830

7.  [Testicular tumours in children: Indications for testis-sparing surgery].

Authors:  Martha Isabel Romo Muñoz; Vanesa Núñez Cerezo; Mariela Dore Reyes; Alejandra Vilanova Sánchez; Pilar González-Peramato; Pedro López Pereira; María José Martínez Urrutia
Journal:  An Pediatr (Engl Ed)       Date:  2017-07-17

8.  Serum alpha fetoprotein (AFP) levels in normal infants.

Authors:  J T Wu; L Book; K Sudar
Journal:  Pediatr Res       Date:  1981-01       Impact factor: 3.756

9.  Testicular adrenal rest tumor screening and fertility counseling among males with congenital adrenal hyperplasia.

Authors:  Monika Chaudhari; Emilie K Johnson; Daniel DaJusta; Leena Nahata
Journal:  J Pediatr Urol       Date:  2017-12-21       Impact factor: 1.830

10.  Testis sparing surgery for pediatric epidermoid cysts of the testis.

Authors:  J H Ross; R Kay; J Elder
Journal:  J Urol       Date:  1993-02       Impact factor: 7.450

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