Literature DB >> 28729185

[Testicular tumours in children: Indications for testis-sparing surgery].

Martha Isabel Romo Muñoz1, Vanesa Núñez Cerezo2, Mariela Dore Reyes2, Alejandra Vilanova Sánchez2, Pilar González-Peramato3, Pedro López Pereira4, María José Martínez Urrutia4.   

Abstract

INTRODUCTION AND
OBJECTIVES: Although standard surgical treatment of a testicular tumour is orchiectomy, use can be made of testis-sparing surgery in selected cases, based on tumour markers, tumour size, and histopathological findings. Our objective is to become acquainted with the indications of testis-sparing surgery as a treatment for the incidental finding of a palpable and non-palpable testicular mass.
MATERIAL AND METHODS: A retrospective study was conducted on 22 patients younger than 18 years diagnosed with a testicular tumour between 2000 and 2014. An assessment was made of the condition, the history, ultrasound, histopathology, tumour markers (BHCG, AFP), therapeutic approach, and outcome.
RESULTS: Of the 22 patients (10 prepubertal age) studied, 82% had palpable mass, and 18% were incidental findings. Two had cryptorchidism. The BHCG was increased in 27% and AFP in 45% of cases. There were 18 tumorectomies and 4 orchiectomies performed. The histopathology found 72% germ cell, 14 orchiectomy, and 2 tumorectomies (2 teratomas), with 27% non-germ cell tumours in 4 orchiectomies and 2 tumorectomies (2 cells of Leydig). Six patients received post-surgical chemotherapy (mixed tumours). The median tumour size was 1 (0.4-1.5) cm in tumorectomies, and 2.5 (0.5-14) cm in orchiectomies. The mean follow-up was 5 (1-15) years. One patient died due to metastatic disease. There was no local recurrence in the follow up of the tumorectomies.
CONCLUSIONS: A change in the trend of our therapeutic approach is demonstrated. We propose that testis-sparing surgery is indicated in prepubertal patients who meet the benignity criteria of the testicular mass (small size and negative tumour markers).
Copyright © 2017 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

Entities:  

Keywords:  Orchiectomy; Orquiectomía; Testicular tumour; Tumor testicular; Tumorectomy; Tumorectomía

Mesh:

Year:  2017        PMID: 28729185     DOI: 10.1016/j.anpedi.2017.05.009

Source DB:  PubMed          Journal:  An Pediatr (Engl Ed)        ISSN: 2341-2879


  2 in total

Review 1.  [Testicular tumors in prepubertal boys-organ preservation possible more often than expected].

Authors:  R Stein; M Dürken; K Zahn; Nina Younsi
Journal:  Urologe A       Date:  2020-03       Impact factor: 0.639

2.  Leydig Cell Tumor-Induced Gonadotropin-Independent Precocious Puberty Progressing to Gonadotropin-Dependent Precocious Puberty Post Orchiectomy: Out of the Frying Pan Into the Fire.

Authors:  Pankaj Singhania; Rana Bhattacharjee; Partha Pratim Chakraborty; Subhankar Chowdhury
Journal:  Cureus       Date:  2022-01-12
  2 in total

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