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Literature DB >> 32019336

Discoveries and developments of CXCR4-targeted HIV-1 entry inhibitors.

Chaozai Zhang^1,2, Ruohan Zhu³, Qizhi Cao⁴, Xiaohong Yang², Ziwei Huang^1,3, Jing An¹.

Abstract

Entities: Species

Keywords: CXCR4; HIV-1 entry inhibitor; V3 loop; X4-tropic; gp120

Mesh：

Substances：

Year: 2020 PMID： 32019336 PMCID： PMC7082890 DOI： 10.1177/1535370220901498

Source DB: PubMed Journal: Exp Biol Med (Maywood) ISSN： 1535-3699

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77 in total

Review 1. Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).

Authors: Won-Tak Choi; Srinivas Duggineni; Yan Xu; Ziwei Huang; Jing An
Journal: J Med Chem Date: 2011-12-02 Impact factor: 7.446

2. Discovery of novel N-aryl piperazine CXCR4 antagonists.

Authors: Huanyu Zhao; Anthony R Prosser; Dennis C Liotta; Lawrence J Wilson
Journal: Bioorg Med Chem Lett Date: 2015-04-17 Impact factor: 2.823

3. A new classification for HIV-1.

Authors: E A Berger; R W Doms; E M Fenyö; B T Korber; D R Littman; J P Moore; Q J Sattentau; H Schuitemaker; J Sodroski; R A Weiss
Journal: Nature Date: 1998-01-15 Impact factor: 49.962

4. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

Authors: L Wu; N P Gerard; R Wyatt; H Choe; C Parolin; N Ruffing; A Borsetti; A A Cardoso; E Desjardin; W Newman; C Gerard; J Sodroski
Journal: Nature Date: 1996-11-14 Impact factor: 49.962

5. Pyrazolo-Piperidines Exhibit Dual Inhibition of CCR5/CXCR4 HIV Entry and Reverse Transcriptase.

Authors: Bryan D Cox; Anthony R Prosser; Yongnian Sun; Zhufang Li; Sangil Lee; Ming B Huang; Vincent C Bond; James P Snyder; Mark Krystal; Lawrence J Wilson; Dennis C Liotta
Journal: ACS Med Chem Lett Date: 2015-05-06 Impact factor: 4.345

6. Early cytoplasmic uncoating is associated with infectivity of HIV-1.

Authors: João I Mamede; Gianguido C Cianci; Meegan R Anderson; Thomas J Hope
Journal: Proc Natl Acad Sci U S A Date: 2017-08-07 Impact factor: 11.205

7. High affinity CXCR4 inhibitors generated by linking low affinity peptides.

Authors: Chaozai Zhang; Lina S Huang; Ruohan Zhu; Qian Meng; Siyu Zhu; Yan Xu; Huijun Zhang; Xiong Fang; Xingquan Zhang; Jiao Zhou; Robert T Schooley; Xiaohong Yang; Ziwei Huang; Jing An
Journal: Eur J Med Chem Date: 2019-04-01 Impact factor: 6.514

8. Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors.

Authors: Chien-Huang Wu; Chuan-Jen Wang; Chun-Ping Chang; Yung-Chi Cheng; Jen-Shin Song; Jiing-Jyh Jan; Ming-Chen Chou; Yi-Yu Ke; Jing Ma; Ying-Chieh Wong; Tsung-Chih Hsieh; Yun-Chen Tien; Elizabeth A Gullen; Chen-Fu Lo; Chia-Yi Cheng; Yu-Wei Liu; Amit A Sadani; Chia-Hua Tsai; Hsin-Pang Hsieh; Lun K Tsou; Kak-Shan Shia
Journal: J Med Chem Date: 2015-01-28 Impact factor: 7.446

9. Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.

Authors: Hirokazu Tamamura; Kenichi Hiramatsu; Satoshi Ueda; Zixuan Wang; Shuichi Kusano; Shigemi Terakubo; John O Trent; Stephen C Peiper; Naoki Yamamoto; Hideki Nakashima; Akira Otaka; Nobutaka Fujii
Journal: J Med Chem Date: 2005-01-27 Impact factor: 7.446

10. Small molecule CXCR4 antagonists block the HIV-1 Nef/CXCR4 axis and selectively initiate the apoptotic program in breast cancer cells.

Authors: Ming-Bo Huang; Kyle E Giesler; Brooke M Katzman; Anthony R Prosser; Valarie Truax; Dennis C Liotta; Lawrence J Wilson; Vincent C Bond
Journal: Oncotarget Date: 2018-02-26

4 in total