Literature DB >> 22085380

Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).

Won-Tak Choi1, Srinivas Duggineni, Yan Xu, Ziwei Huang, Jing An.   

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Year:  2011        PMID： 22085380      PMCID： PMC3476736          DOI： 10.1021/jm200568c

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  199 in total

1.  Involvement of p90rsk in neurite outgrowth mediated by the cell adhesion molecule L1.

Authors:  E V Wong; A W Schaefer; G Landreth; V Lemmon
Journal:  J Biol Chem       Date:  1996-07-26       Impact factor: 5.157

2.  Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor.

Authors:  L O Gerlach; R T Skerlj; G J Bridger; T W Schwartz
Journal:  J Biol Chem       Date:  2001-01-11       Impact factor: 5.157

3.  Colony growth of human leukemic peripheral blood cells in vitro.

Authors:  W A Robinson; J E Kurnick; B L Pike
Journal:  Blood       Date:  1971-10       Impact factor: 22.113

4.  Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry.

Authors:  Mike Westby; Caroline Smith-Burchnell; Julie Mori; Marilyn Lewis; Michael Mosley; Mark Stockdale; Patrick Dorr; Giuseppe Ciaramella; Manos Perros
Journal:  J Virol       Date:  2006-12-20       Impact factor: 5.103

5.  The CXCR4 agonist peptide, CTCE-0021, rapidly mobilizes polymorphonuclear neutrophils and hematopoietic progenitor cells into peripheral blood and synergizes with granulocyte colony-stimulating factor.

Authors:  Louis M Pelus; Huimin Bian; Seiji Fukuda; Donald Wong; Ahmed Merzouk; Hassan Salari
Journal:  Exp Hematol       Date:  2005-03       Impact factor: 3.084

6.  Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

Authors:  Bruno Nervi; Pablo Ramirez; Michael P Rettig; Geoffrey L Uy; Matthew S Holt; Julie K Ritchey; Julie L Prior; David Piwnica-Worms; Gary Bridger; Timothy J Ley; John F DiPersio
Journal:  Blood       Date:  2008-12-02       Impact factor: 22.113

7.  JNK phosphorylates paxillin and regulates cell migration.

Authors:  Cai Huang; Zenon Rajfur; Christoph Borchers; Michael D Schaller; Ken Jacobson
Journal:  Nature       Date:  2003-07-10       Impact factor: 49.962

8.  Cloning and characterization of the guinea pig eosinophil eotaxin receptor, C-C chemokine receptor-3: blockade using a monoclonal antibody in vivo.

Authors:  I Sabroe; D M Conroy; N P Gerard; Y Li; P D Collins; T W Post; P J Jose; T J Williams; C J Gerard; P D Ponath
Journal:  J Immunol       Date:  1998-12-01       Impact factor: 5.422

9.  Poor expression of T cell-derived cytokines and activation and proliferation markers in early rheumatoid synovial tissue.

Authors:  T J Smeets; A M Miltenburg; R de Kuiper; F C Breedveld; P P Tak
Journal:  Clin Immunol Immunopathol       Date:  1998-07

10.  High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane.

Authors:  S B Cohen; P D Katsikis; C Q Chu; H Thomssen; L M Webb; R N Maini; M Londei; M Feldmann
Journal:  Arthritis Rheum       Date:  1995-07
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  33 in total

1.  In vivo Evaluation of an Engineered Cyclotide as Specific CXCR4 Imaging Reagent.

Authors:  Wojciech G Lesniak; Teshome Aboye; Samit Chatterjee; Julio A Camarero; Sridhar Nimmagadda
Journal:  Chemistry       Date:  2017-08-03       Impact factor: 5.236

2.  A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry.

Authors:  Won-Tak Choi; Santhosh Kumar; Navid Madani; Xiaofeng Han; Shaomin Tian; Chang-Zhi Dong; Dongxiang Liu; Srinivas Duggineni; Jian Yuan; Joseph G Sodroski; Ziwei Huang; Jing An
Journal:  Biochemistry       Date:  2012-08-29       Impact factor: 3.162

3.  Discovery of novel N-aryl piperazine CXCR4 antagonists.

Authors:  Huanyu Zhao; Anthony R Prosser; Dennis C Liotta; Lawrence J Wilson
Journal:  Bioorg Med Chem Lett       Date:  2015-04-17       Impact factor: 2.823

4.  Discovery of N-Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties.

Authors:  Yesim A Tahirovic; Valarie M Truax; Robert J Wilson; Edgars Jecs; Huy H Nguyen; Eric J Miller; Michelle B Kim; Katie M Kuo; Tao Wang; Chi S Sum; Mary E Cvijic; Gretchen M Schroeder; Lawrence J Wilson; Dennis C Liotta
Journal:  ACS Med Chem Lett       Date:  2018-04-09       Impact factor: 4.345

Review 5.  Bivalent ligands targeting chemokine receptor dimerization: molecular design and functional studies.

Authors:  Christopher Kent Arnatt; Yan Zhang
Journal:  Curr Top Med Chem       Date:  2014       Impact factor: 3.295

6.  High affinity CXCR4 inhibitors generated by linking low affinity peptides.

Authors:  Chaozai Zhang; Lina S Huang; Ruohan Zhu; Qian Meng; Siyu Zhu; Yan Xu; Huijun Zhang; Xiong Fang; Xingquan Zhang; Jiao Zhou; Robert T Schooley; Xiaohong Yang; Ziwei Huang; Jing An
Journal:  Eur J Med Chem       Date:  2019-04-01       Impact factor: 6.514

7.  Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors.

Authors:  Chien-Huang Wu; Chuan-Jen Wang; Chun-Ping Chang; Yung-Chi Cheng; Jen-Shin Song; Jiing-Jyh Jan; Ming-Chen Chou; Yi-Yu Ke; Jing Ma; Ying-Chieh Wong; Tsung-Chih Hsieh; Yun-Chen Tien; Elizabeth A Gullen; Chen-Fu Lo; Chia-Yi Cheng; Yu-Wei Liu; Amit A Sadani; Chia-Hua Tsai; Hsin-Pang Hsieh; Lun K Tsou; Kak-Shan Shia
Journal:  J Med Chem       Date:  2015-01-28       Impact factor: 7.446

8.  Synthesis of pyridine derivatives as potential antagonists of chemokine receptor type 4.

Authors:  Suazette Reid Mooring; Theresa Gaines; Zhongxing Liang; Hyunsuk Shim
Journal:  Heterocycl Comm       Date:  2014-05       Impact factor: 1.120

9.  Discovery of tetrahydroisoquinoline-based CXCR4 antagonists.

Authors:  Valarie M Truax; Huanyu Zhao; Brooke M Katzman; Anthony R Prosser; Ana A Alcaraz; Manohar T Saindane; Randy B Howard; Deborah Culver; Richard F Arrendale; Prahbakar R Gruddanti; Taylor J Evers; Michael G Natchus; James P Snyder; Dennis C Liotta; Lawrence J Wilson
Journal:  ACS Med Chem Lett       Date:  2013-09-05       Impact factor: 4.345

10.  Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity.

Authors:  Teshome L Aboye; Helen Ha; Subhabrata Majumder; Frauke Christ; Zeger Debyser; Alexander Shekhtman; Nouri Neamati; Julio A Camarero
Journal:  J Med Chem       Date:  2012-11-27       Impact factor: 7.446
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