| Literature DB >> 32010274 |
Manabu Miyamoto1, George Imataka1, Go Ichikawa1, Yutaka Saito2, Takashi Kashiwagi3, Yoshiyuki Kaji2, Koji Wake2, Kei Funakoshi4, Takahide Nagashima4, Norito Kokubun4, Shigemi Yoshihara1.
Abstract
Childhood Guillain-Barré syndrome (GBS) occasionally leads to respiratory failure early after onset, requiring long-term ventilation management after tracheal intubation. However, patients requiring tracheostomy management are rare. In the present study, a case of a 12-year-old boy with GBS who required artificial respiration management due to rapid progression of respiratory muscle paralysis is reported. Intravenous immunoglobulin (IVIg) and pulse steroid therapy were provided; however, both were ineffective and tracheostomy was necessary 26 days after onset. A second course of IVIg and pulse steroid therapy was administered on day 34. With continued rehabilitation, the patient was able to walk long distances on day 74 and was subsequently discharged on day 89. In cases of severe GBS, when IVIg and pulse steroid therapy do not improve the respiratory muscle strength of the patient, early tracheostomy may improve the patient's quality of life during artificial respiration management.Entities:
Keywords: Guillain-Barré syndrome; children; immunoglobulin; steroid pulse; tracheostomy
Year: 2019 PMID: 32010274 PMCID: PMC6966195 DOI: 10.3892/etm.2019.8311
Source DB: PubMed Journal: Exp Ther Med ISSN: 1792-0981 Impact factor: 2.447