| Literature DB >> 31992243 |
Stephen E Hudson1, Matthew S Feigenbaum2, Nirav Patil3, Elan Ding3, Alex Ewing3, Jennifer L Trilk3.
Abstract
BACKGROUND: The Southern region of the United States is home to substantial populations with obesity, dyslipidemia, and hypertriglyceridemia, while also housing a large percentage of America's minority, rural, and low socioeconomic status (SES) peoples. Adult-onset cardiovascular disease (CVD) research may be informed by investigating associations(s) between late adolescent demographic variables and lipid values. Our objective was to investigate lipid parameter associations with college-age socioeconomic status, which may improve age-specific screening algorithms for management or prevention of adult-onset CVD.Entities:
Keywords: Cardiovascular disease; High-density lipoprotein; Lipid; Low-density lipoprotein; Socioeconomic status
Mesh:
Substances:
Year: 2020 PMID: 31992243 PMCID: PMC6986140 DOI: 10.1186/s12889-019-8099-9
Source DB: PubMed Journal: BMC Public Health ISSN: 1471-2458 Impact factor: 3.295
Fig. 1College Lipid Data versus Nationally Comparative Lipid Data (Parts A, B, and C). Part A Total Cholesterol Values (Furman Database vs. NHANES Data). Part B HDL-C Cholesterol Values (Furman Database vs. NHANES Data). Part C Triglyceride Values (Furman Database vs. NHANES Data). Legend: NHANES = National Health and Nutrition Examination Survey. Income categories defined in college (solid lines) population data as Higher (mean ~$186k), Middle (mean ~$169k), and Lower (mean ~$86k) categories using annual family income respectively (as reported by Free Application for Federal Student Aid data). For NHANES, Higher Income >$75k, Lower Income < $20k, and Middle Income between $20k and $75k
Average university student lipid parameters by race, financial need, gender, and athletic participation, 2003–15*,**
| TCa | TG | HDL-Ca | VLDL-C | LDL-C | ||
|---|---|---|---|---|---|---|
| Race | ||||||
| Caucasian | 3697 | 160.2 (158.1, 162.2) | 89.2 (86.4, 92.0) | 55.7 (54.8, 56.5) | 17.7 (17.1, 18.2) | 86.4 (84.7, 88.1) |
| African-American | 227 | 161.2 (157.1, 165.3) | 88.6 (85.3, 92.0) | |||
| Asian | 169 | 164.8 (160.0, 169.6) | 91.5 (84.9, 98.1) | 57.7 (55.8, 59.7) | 18.1 (16.8, 19.5) | 88.6 (84.6, 92.6) |
| Hispanic | 139 | 161.8 (156.6, 166.9) | 89.4 (82.3, 96.5) | 56.6 (54.5, 58.7) | 17.7 (16.3, 19.1) | 87.1 (82.9, 91.4) |
| Others | 191 | 160.9 (156.5, 165.4) | 87.5 (81.4, 93.6) | 55.8 (54.0, 57.6) | 17.3 (16.0, 18.5) | 87.4 (83.7, 91.1) |
| Financial Need Status b | ||||||
| High need (~$86 k) | 1387 | 159.7 (157.2, 162.2) | 82.2 (78.7, 85.6) | 56.5 (55.5, 57.5) | 16.3 (15.6, 17.0) | 86.4 (84.3, 88.4) |
| Medium need (~$169 k) | 234 | 87.7 (81.8, 93.6) | 57.7 (56.0, 59.5) | 17.3 (16.1, 18.5) | 90.1 (86.5, 93.7) | |
| Low need (~$182 k) | 2802 | 160.1 (157.8, 162.4) | 83.7 (80.5, 86.8) | 56.8 (55.9, 57.8) | 16.5 (15.9, 17.1) | 86.4 (84.5, 88.3) |
| Gender | ||||||
| Female | 2605 | 84.2 (80.6, 87.7) | 16.6 (15.9, 17.4) | |||
| Male | 1818 | 84.8 (81.2, 88.5) | 16.7 (16.0, 17.5) | |||
| Athletic Participation | ||||||
| Yes | 331 | 161.2 (157.6, 164.8) | 82.8 (77.8, 87.8) | 16.3 (15.3, 17.3) | 86.5 (83.4, 89.5) | |
| No | 4092 | 162.4 (160.3, 164.4) | 86.2 (83.4, 89.1) | 17.1 (16.4, 17.6) | 88.8 (87.1, 90.5) | |
TC Total Cholesterol, TG Triglyceride, HDL-C High-Density Lipoprotein, VLDL-C Very Low-Density Lipoprotein, LDL-C Low-Density Lipoprotein. All data measured in milligrams per deciliter (mg/dL). Data are presented as means followed by 95% confidence interval in parentheses
*General Linear model p-values. Adjustment is made for race, gender, financial need status, athletic participation and Age. P-Values less than 0.05 are considered significant and underlined and bolded
**Post-hoc multiple pair-wise comparison using Tukey’s adjustment
aNo significant interaction between Race, Gender and Athletic participation b Not all students had FAFSAs (Free Application for Federal Student Aid)
NHANES Lipid Data (Age-Matched Nationally Representative Population), Years 2003-16
| Average 2003-16 NHANES Lipid Values by Race, Gender, and Incomeb,c | |||||
|---|---|---|---|---|---|
| N: 4370 | Total Cholesterol | HDL-Ca | N: 2221 | Triglyceride | |
| Race | |||||
| Caucasian | 1610 | 172.7 (171.1, 174.4) | 47.0 (46.0, 48.0) | 781 | 106.3 (101.1, 111.5) |
| African-American | 1137 | 168.8 (167.0, 170.6) | 50.6 (49.3, 51.8) | 575 | |
| Mexican | 771 | 170.4 (168.1, 172.6) | 48.1 (46.8, 49.4) | 400 | 110.6 (103.7, 117.4) |
| Hispanic | 333 | 167.9 (164.3, 171.4) | 48.1 (46.2, 50.0) | 181 | 104.0 (94.8, 113.1) |
| Others | 519 | 172.8 (169.9, 175.6) | 50.0 (48.3, 51.6) | 284 | 90.2 (84.0, 96.5) |
| Income | |||||
| High | 745 | 171.6 (169.3, 174.0) | 47.0 (45.6, 48.5) | 408 | 99.5 (94.1, 104.9) |
| Medium | 1521 | 172.0 (170.5, 173.6) | 48.1 (47.2, 49.0) | 792 | 97.9 (93.9, 101.8) |
| Low | 1902 | 171.2 (169.6, 172.9) | 48.3 (47.3, 49.3) | 1021 | 105.4 (99.6, 111.2) |
| Gender | |||||
| Female | 2304 | 1187 | |||
| Male | 2066 | 168.8 (167.4, 170.1) | 44.1 (43.3, 44.9) | 1034 | 107.4 (103.0, 111.9) |
aHDL-C High-Density Lipoprotein
bAll data measured in milligrams per deciliter (mg/dL) and are available from the National Health and Nutrition Examination Survey. Data are presented as means followed by 95% confidence interval in parentheses. As in Table 1, adjustment is made for race, gender, financial need status, athletic participation and Age. P-Values less than 0.05 are considered significant and underlined and bolded
cPost-hoc multiple pair-wise comparison using Tukey’s adjustment