Shabana Rasheed Ziyad 1 , Venkatachalam Radha 2 , Thavavel Vayyapuri 1 . Show Affiliations »
Abstract
BACKGROUND: Lung cancer has become a major cause of cancer-related deaths. Detection of potentially malignant lung nodules is essential for the early diagnosis and clinical management of lung cancer. In clinical practice, the interpretation of Computed Tomography (CT) images is challenging for radiologists due to a large number of cases. There is a high rate of false positives in the manual findings. Computer aided detection system (CAD) and computer aided diagnosis systems (CADx) enhance the radiologists in accurately delineating the lung nodules. OBJECTIVES: The objective is to analyze CAD and CADx systems for lung nodule detection. It is necessary to review the various techniques followed in CAD and CADx systems proposed and implemented by various research persons. This study aims at analyzing the recent application of various concepts in computer science to each stage of CAD and CADx. METHODS: This review paper is special in its own kind because it analyses the various techniques proposed by different eminent researchers in noise removal, contrast enhancement, thorax removal, lung segmentation, bone suppression, segmentation of trachea, classification of nodule and nonnodule and final classification of benign and malignant nodules. RESULTS: A comparison of the performance of different techniques implemented by various researchers for the classification of nodule and non-nodule has been tabulated in the paper. CONCLUSION: The findings of this review paper will definitely prove to be useful to the research community working on automation of lung nodule detection. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
BACKGROUND: Lung cancer has become a major cause of cancer -related deaths. Detection of potentially malignant lung nodules is essential for the early diagnosis and clinical management of lung cancer . In clinical practice, the interpretation of Computed Tomography (CT) images is challenging for radiologists due to a large number of cases. There is a high rate of false positives in the manual findings. Computer aided detection system (CAD) and computer aided diagnosis systems (CADx) enhance the radiologists in accurately delineating the lung nodules. OBJECTIVES: The objective is to analyze CAD and CADx systems for lung nodule detection. It is necessary to review the various techniques followed in CAD and CADx systems proposed and implemented by various research persons . This study aims at analyzing the recent application of various concepts in computer science to each stage of CAD and CADx. METHODS: This review paper is special in its own kind because it analyses the various techniques proposed by different eminent researchers in noise removal, contrast enhancement, thorax removal, lung segmentation, bone suppression, segmentation of trachea, classification of nodule and nonnodule and final classification of benign and malignant nodules. RESULTS: A comparison of the performance of different techniques implemented by various researchers for the classification of nodule and non-nodule has been tabulated in the paper. CONCLUSION: The findings of this review paper will definitely prove to be useful to the research community working on automation of lung nodule detection. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
Entities: Disease
Species
Keywords:
Lung cancer; computed tomography; lung nodules; lung segmentation; nodule classification; noise removal.
Year: 2020
PMID: 31989890 DOI: 10.2174/1573405615666190206153321
Source DB: PubMed Journal: Curr Med Imaging Rev ISSN: 1573-4056