Literature DB >> 319871

Metabolic effects of salbutamol: comparison of aerosol and intravenous administration.

A Neville, J B Palmer, J Gaddie, C S May, K N Palmer, L E Murchison.   

Abstract

The effects of intravenous salbutamol (4 mug/kg) were compared with those of aerosol salbutamol (200 mug) in 10 asthmatic patients in a double-blind placebo-controlled study. Both methods of administration produced equal bronchodilatation. Intravenous salbutamol caused significant increases in plasma insulin and glucose levels and a fall in serum potassium concentration in addition to tachycardia and tremor, whereas aerosol salbutamol produced only a small transient increase in the plasma glucose level. The initially raised non-esterified fatty acid levels decreased significantly after aerosol and placebo but not after intravenous salbutamol.

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Year:  1977        PMID: 319871      PMCID: PMC1604822          DOI: 10.1136/bmj.1.6058.413

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  10 in total

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Journal:  Am J Med       Date:  1964-11       Impact factor: 4.965

Review 2.  Metabolic response during impending myocardial infarction. II. Clinical implications.

Authors:  M F Oliver
Journal:  Circulation       Date:  1972-02       Impact factor: 29.690

3.  Electrophysiologic properties of isolated preparations of human atrial myocardium.

Authors:  H Gelband; H L Bush; M R Rosen; R J Myerburg; B F Hoffman
Journal:  Circ Res       Date:  1972-03       Impact factor: 17.367

4.  Effects of epinephrine on asthmatic children. Effects of epinephrine on blood glucose, pulmonary function, and heart rate of children with asthma of varying severity.

Authors:  S Inoue
Journal:  J Allergy       Date:  1967-12

5.  Metabolic response to epinephrine in bronchial asthma.

Authors:  E Middleton; S R Finke
Journal:  J Allergy       Date:  1968-11

6.  Metabolic effects of oral salbutamol.

Authors:  M W Taylor; J Gaddie; L E Murchison; K N Palmer
Journal:  Br Med J       Date:  1976-01-03

7.  Bronchodilators. Part I.

Authors:  J W Paterson; G M Shenfield
Journal:  BTTA Rev       Date:  1974-06

8.  Treatment of attacks in hyperkalaemic familial periodic paralysis by inhalation of salbutamol.

Authors:  P Wang; T Clausen
Journal:  Lancet       Date:  1976-01-31       Impact factor: 79.321

9.  Metabolic response during impending myocardial infarction. I. Relevance of studies of glucose and fatty acid metabolism in animals.

Authors:  L H Opie
Journal:  Circulation       Date:  1972-02       Impact factor: 29.690

10.  The cardio-toxicity of isoprenaline during hypoxia.

Authors:  J M Collins; D G McDevitt; R G Shanks; J G Swanton
Journal:  Br J Pharmacol       Date:  1969-05       Impact factor: 8.739

  10 in total
  21 in total

1.  Effects of salbutamol and metoprolol on plasma renin activity and plasma potassium of normal subjects and of hypertensive patients.

Authors:  A Salvetti; L Poli; F Arzilli; L Sassano; R Pedrinelli; M Motolese
Journal:  J Endocrinol Invest       Date:  1978-01       Impact factor: 4.256

2.  Hypokalaemia and other non-bronchial effects of inhaled fenoterol and salbutamol: a placebo-controlled dose-response study in healthy volunteers.

Authors:  M Scheinin; M Koulu; E Laurikainen; H Allonen
Journal:  Br J Clin Pharmacol       Date:  1987-11       Impact factor: 4.335

3.  Modulation of the effects of salbutamol by propranolol and atenolol.

Authors:  N A Minton; A R Baird; J A Henry
Journal:  Eur J Clin Pharmacol       Date:  1989       Impact factor: 2.953

4.  Estimation of HbA1c in hospitalized patients with bronchial asthma.

Authors:  Bayar Qasim; Safer Haj; Herish Ahmed
Journal:  Endocrine       Date:  2017-09-07       Impact factor: 3.633

5.  Effect of eight months of inhaled beclomethasone dipropionate and budesonide on carbohydrate metabolism in adults with asthma.

Authors:  K Kiviranta; M Turpeinen
Journal:  Thorax       Date:  1993-10       Impact factor: 9.139

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Authors:  S G Nogrady; J P Hartley; A Seaton
Journal:  Thorax       Date:  1977-10       Impact factor: 9.139

Review 7.  Fenoterol: a review of its pharmacological properties and therapeutic efficacy in asthma.

Authors:  R C Heel; R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-01       Impact factor: 9.546

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Authors:  K F Whyte; G J Addis; R Whitesmith; J L Reid
Journal:  Br J Clin Pharmacol       Date:  1987-01       Impact factor: 4.335

9.  Salbutamol disposition and dynamics in conscious rabbits: influence of the route of administration and of the dose.

Authors:  S Perreault; H Ong; P du Souich
Journal:  J Pharmacokinet Biopharm       Date:  1992-10

10.  Sustained bronchodilation with isoproterenol poly(glycolide-co-lactide) microspheres.

Authors:  Y L Lai; R C Mehta; A A Thacker; S D Yoo; P J McNamara; P P DeLuca
Journal:  Pharm Res       Date:  1993-01       Impact factor: 4.200

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