Literature DB >> 3197702

Inhibitory effect of a mixture of herbal drugs (TJ-960, SK) on pentylenetetrazol-induced convulsions in E1 mice.

E Sugaya1, A Ishige, K Sekiguchi, S Iizuka, A Sugimoto, M Yuzurihara, E Hosoya.   

Abstract

TJ-960 is a spray-dried mixture of 9 herbal drugs. The convulsions of E1 mice induced by pentylenetetrazol (18 mg/kg) were completely inhibited by p.o. administration of TJ-960 at a daily dose of 1.0 g/kg both in 8-week-old and 4-week-old E1 mice. These findings suggest that TJ-960 has an inhibitory effect on the convulsions of this hereditary animal model of epilepsy.

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Year:  1988        PMID： 3197702     DOI： 10.1016/0920-1211(88)90043-5

Source DB:  PubMed          Journal:  Epilepsy Res        ISSN： 0920-1211            Impact factor:   3.045


  3 in total

1.  Increased choline acetyltransferase activity by Chinese herbal medicine Sho-saiko-to-go-keishi-ka-shakuyaku-to in aged rat brain.

Authors:  M Hiramatsu; K Haba; R Edamatsu; H Hamada; A Mori
Journal:  Neurochem Res       Date:  1989-03       Impact factor: 3.996

2.  The effects of sho-saiko-to-go-keishi-ka-shakuyaku-to (TJ-960) on ischemia-induced changes of brain acetylcholine and monoamine levels in gerbils.

Authors:  K Haba; N Ogawa; A Mori
Journal:  Neurochem Res       Date:  1990-05       Impact factor: 3.996

3.  Anticonvulsive effect of paeoniflorin on experimental febrile seizures in immature rats: possible application for febrile seizures in children.

Authors:  Hitomi Hino; Hisaaki Takahashi; Yuka Suzuki; Junya Tanaka; Eiichi Ishii; Mitsumasa Fukuda
Journal:  PLoS One       Date:  2012-08-16       Impact factor: 3.240
  3 in total

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