| Literature DB >> 3197696 |
O A Nielsen1, A C Johannessen, B Bardrum.
Abstract
In order to estimate the frequency of hyponatremia in patients treated with oxcarbazepine (OxCZ), a cross-sectional study was carried out. 21 of 41 patients being treated with the drug were found to be hyponatremic (serum sodium levels less than 135 mmol/l). None was found to be hypernatremic (serum sodium levels greater than 145 mmol/l). A non-significant trend towards increasing frequency of hyponatremia with increasing age was observed. Patients treated with dosages above 30 mg/kg/day had a significantly higher risk of becoming hyponatremic.Entities:
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Year: 1988 PMID： 3197696 DOI： 10.1016/0920-1211(88)90018-6
Source DB: PubMed Journal: Epilepsy Res ISSN： 0920-1211 Impact factor: 3.045