Literature DB >> 31970050

Vacuum-Assisted Closure: An Effective Technique to Manage Wound Complications After Metastatic Spine Tumour Surgery (MSTS)-A Case Report.

Ravish Shammi Patel1, Samuel Sherng Young Wang2, Miguel Rafael David Ramos1, Husam Walid Naji Najjar3, Samuel Vara Prasad4, Naresh Kumar1.   

Abstract

The management of wound complications following metastatic spine tumor surgery (MSTS) remains a formidable task. Plastic coverage procedures after MSTS are challenging due to unhealthy donor sites following previous radiotherapy and prolonged nonambulation. Negative pressure wound therapy (NPWT) is usually not recommended after MSTS due to fear of tumor seeding and excessive blood loss. However, in certain patients post-MSTS, who may be considered as receiving palliative treatment, NPWT can be effective in managing wound complications. We describe our initial experience with the use of NPWT in a 57-year-old lady diagnosed with multiple lumbar and cervicothoracic vertebral metastases secondary to non-small cell lung carcinoma. She underwent 2 cycles of preoperative radiotherapy followed by decompression and posterior instrumentation of lumbosacral and cervicothoracic regions succeeded by another cycle of radiotherapy. The patient developed wound dehiscence and poly-microbial surgical site infection that was not responsive to regular debridements and antibiotics. Hence, we applied NPWT as an alternative treatment to plastic surgical procedures. The patient clinically improved with a reduced quantity of wound discharge, increased granulation tissue, and a downward trend in the inflammatory markers. Subsequently, wound was secondarily closed after 14 days. The patient was discharged after a total hospital stay of 41 days. The intravenous antibiotics (piperacillin/tazobactam) were changed to oral (ciprofloxacin) after 6 weeks and continued for 4 months. The patient survived for 3 years without any wound complications. Our case report suggests that NPWT can be a potential treatment option for managing wound complications following MSTS. ©International Society for the Advancement of Spine Surgery 2019.

Entities:  

Keywords:  NPWT; metastatis; negative pressure wound therapy; spine surgery; surgical site infections; vacuum-assisted closure, VAC; wound complications

Year:  2019        PMID: 31970050      PMCID: PMC6962007          DOI: 10.14444/6074

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  29 in total

1.  Vacuum-assisted closure: microdeformations of wounds and cell proliferation.

Authors:  Vishal Saxena; Chao-Wei Hwang; Sui Huang; Quentin Eichbaum; Donald Ingber; Dennis P Orgill
Journal:  Plast Reconstr Surg       Date:  2004-10       Impact factor: 4.730

2.  Use of vacuum assisted closure therapy in the palliation of a malignant wound.

Authors:  Suzanne Ford-Dunn
Journal:  Palliat Med       Date:  2006-06       Impact factor: 4.762

3.  Vacuum-assisted closure: a new method for wound control and treatment: clinical experience.

Authors:  L C Argenta; M J Morykwas
Journal:  Ann Plast Surg       Date:  1997-06       Impact factor: 1.539

Review 4.  Radiation responses in skin and connective tissues: effect on wound healing and surgical outcome.

Authors:  Junru Wang; Marjan Boerma; Qiang Fu; Martin Hauer-Jensen
Journal:  Hernia       Date:  2006-12       Impact factor: 4.739

5.  Comparison of the effect of bacterial inoculation in musculocutaneous and fasciocutaneous flaps.

Authors:  W Calderon; N Chang; S J Mathes
Journal:  Plast Reconstr Surg       Date:  1986-05       Impact factor: 4.730

6.  Is the use of negative pressure wound therapy for a malignant wound legitimate in a palliative context? "The concept of NPWT ad vitam": A case series.

Authors:  Samuel Riot; Guillaume de Bonnecaze; Ignacio Garrido; Gwenaël Ferron; Jean-Louis Grolleau; Benoit Chaput
Journal:  Palliat Med       Date:  2014-12-18       Impact factor: 4.762

7.  Negative pressure wound therapy for at-risk surgical closures in patients with multiple comorbidities: a prospective randomized controlled study.

Authors:  Derek Masden; Jesse Goldstein; Mathew Endara; Kyle Xu; John Steinberg; Christopher Attinger
Journal:  Ann Surg       Date:  2012-06       Impact factor: 12.969

8.  Reconstructive strategies in soft tissue reconstruction after resection of spinal neoplasms.

Authors:  David W Chang; Michael T Friel; Adel A Youssef
Journal:  Spine (Phila Pa 1976)       Date:  2007-05-01       Impact factor: 3.468

9.  Negative-pressure wound therapy in the treatment of complex postoperative spinal wound infections: complications and lessons learned using vacuum-assisted closure.

Authors:  G Alexander Jones; John Butler; Isador Lieberman; Richard Schlenk
Journal:  J Neurosurg Spine       Date:  2007-05

10.  Wound management with vacuum-assisted closure in postoperative infections after surgery for spinal stenosis.

Authors:  Fatih Karaaslan; Şevki Erdem; Musa Uğur Mermerkaya
Journal:  Int Med Case Rep J       Date:  2014-12-22
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