Literature DB >> 3196009

Antibacterial effect of etoposide in vitro.

W Calame1, R van der Waals, N Douwes-Idema, H Mattie, R van Furth.   

Abstract

Etoposide, an antitumor drug, had an effect in vitro against all strains of gram-positive bacteria studied but not against three gram-negative bacteria. The MICs ranged between 6.2 and 50 micrograms/ml. In short-term-growth experiments, etoposide had a bactericidal efficacy that was 10 to 50 times lower than that of cloxacillin.

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Year:  1988        PMID： 3196009      PMCID： PMC175891          DOI： 10.1128/AAC.32.9.1456

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Effect of VP-16-213 on the intracellular degradation of DNA in HeLa cells.

Authors:  J D Loike; S B Horwitz
Journal:  Biochemistry       Date:  1976-12-14       Impact factor: 3.162

2.  Cefazolin and cephradine: relationship between antibacterial activity in vitro and in mice experimentally infected with Escherichia coli.

Authors:  M W Kunst; H Mattie
Journal:  J Infect Dis       Date:  1978-04       Impact factor: 5.226

3.  Cloxacillin and nafcillin: serum binding and its relationship to antibacterial effect in mice.

Authors:  H Mattie; W R Goslings; E L Noach
Journal:  J Infect Dis       Date:  1973-08       Impact factor: 5.226

4.  Structure-activity study of the inhibition of microtubule assembly in vitro by podophyllotoxin and its congeners.

Authors:  J D Loike; C F Brewer; H Sternlicht; W J Gensler; S B Horwitz
Journal:  Cancer Res       Date:  1978-09       Impact factor: 12.701

Review 5.  VP16-213 (etoposide). A critical review of its activity.

Authors:  F Cavalli
Journal:  Cancer Chemother Pharmacol       Date:  1982       Impact factor: 3.333

6.  The relative potency of amoxycillin and ampicillin in vitro and in vivo.

Authors:  H Mattie; G B van der Voet
Journal:  Scand J Infect Dis       Date:  1981

7.  Standardization of antibiotic sensitivity tests.

Authors:  R P Mouton; B van Klingeren
Journal:  Scand J Infect Dis       Date:  1982

Review 8.  Etoposide (VP-16-213). Current status of an active anticancer drug.

Authors:  P J O'Dwyer; B Leyland-Jones; M T Alonso; S Marsoni; R E Wittes
Journal:  N Engl J Med       Date:  1985-03-14       Impact factor: 91.245

9.  Effects of the epipodophyllotoxin VP-16-213 on cell cycle traverse, DNA synthesis, and DNA strand size in cultures of human leukemic lymphoblasts.

Authors:  D K Kalwinsky; A T Look; J Ducore; A Fridland
Journal:  Cancer Res       Date:  1983-04       Impact factor: 12.701

10.  Pharmacokinetics of VP16-213 given by different administration methods.

Authors:  M D'Incalci; P Farina; C Sessa; C Mangioni; V Conter; G Masera; M Rocchetti; M B Pisoni; E Piazza; M Beer; F Cavalli
Journal:  Cancer Chemother Pharmacol       Date:  1982       Impact factor: 3.333
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  3 in total

Review 1.  A "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.

Authors:  Gregory S Bisacchi; Michael R Hale
Journal:  Curr Med Chem       Date:  2016       Impact factor: 4.530

2.  Influence of etoposide and cyclophosphamide on the efficacy of cloxacillin and erythromycin in an experimental staphylococcal infection.

Authors:  W Calame; R van der Waals; H Mattie; R van Furth
Journal:  Antimicrob Agents Chemother       Date:  1989-06       Impact factor: 5.191

3.  Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.

Authors:  Pan F Chan; Velupillai Srikannathasan; Jianzhong Huang; Haifeng Cui; Andrew P Fosberry; Minghua Gu; Michael M Hann; Martin Hibbs; Paul Homes; Karen Ingraham; Jason Pizzollo; Carol Shen; Anthony J Shillings; Claus E Spitzfaden; Robert Tanner; Andrew J Theobald; Robert A Stavenger; Benjamin D Bax; Michael N Gwynn
Journal:  Nat Commun       Date:  2015-12-07       Impact factor: 14.919
  3 in total

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