| Literature DB >> 31958406 |
Frank Jessen1, Rebecca E Amariglio2, Rachel F Buckley3, Wiesje M van der Flier4, Ying Han5, José Luis Molinuevo6, Laura Rabin7, Dorene M Rentz2, Octavio Rodriguez-Gomez8, Andrew J Saykin9, Sietske A M Sikkes10, Colette M Smart11, Steffen Wolfsgruber12, Michael Wagner13.
Abstract
A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired individuals, who are concerned that they have reduced cognitive function, to approach the medical system for help. The term subjective cognitive decline (SCD) was conceived in 2014 to describe this condition. Epidemiological data provide evidence that the risk for mild cognitive impairment and dementia is increased in individuals with SCD. However, the majority of individuals with SCD will not show progressive cognitive decline. An individually tailored diagnostic process might be reasonable to identify or exclude underlying medical conditions in an individual with SCD who actively seeks medical help. An increasing number of studies are investigating the link between SCD and the very early stages of Alzheimer's disease and other neurodegenerative diseases.Entities:
Mesh:
Year: 2020 PMID: 31958406 PMCID: PMC7062546 DOI: 10.1016/S1474-4422(19)30368-0
Source DB: PubMed Journal: Lancet Neurol ISSN: 1474-4422 Impact factor: 44.182