Literature DB >> 3194754

Cloning of a membrane protein that induces a slow voltage-gated potassium current.

T Takumi1, H Ohkubo, S Nakanishi.   

Abstract

A rat kidney messenger RNA that induces a slowly activating, voltage-dependent potassium current on its expression in Xenopus oocytes was identified by combining molecular cloning with an electrophysiological assay. The cloned complementary DNA encodes a novel membrane protein that consists of 130 amino acids with a single putative transmembrane domain. This protein differs from the known ion channel proteins but is involved in the induction of selective permeation of potassium ions by membrane depolarization.

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Year:  1988        PMID: 3194754     DOI: 10.1126/science.3194754

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  142 in total

Review 1.  Molecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium.

Authors:  J M Nerbonne
Journal:  J Physiol       Date:  2000-06-01       Impact factor: 5.182

2.  Heterologous expression of the Na(+),K(+)-ATPase gamma subunit in Xenopus oocytes induces an endogenous, voltage-gated large diameter pore.

Authors:  Q Sha; K L Lansbery; D Distefano; R W Mercer; C G Nichols
Journal:  J Physiol       Date:  2001-09-01       Impact factor: 5.182

3.  A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly.

Authors:  N Schmitt; M Schwarz; A Peretz; I Abitbol; B Attali; O Pongs
Journal:  EMBO J       Date:  2000-02-01       Impact factor: 11.598

4.  KCNE4 is an inhibitory subunit to the KCNQ1 channel.

Authors:  Morten Grunnet; Thomas Jespersen; Hanne Borger Rasmussen; Trine Ljungstrøm; Nanna K Jorgensen; Søren-Peter Olesen; Dan A Klaerke
Journal:  J Physiol       Date:  2002-07-01       Impact factor: 5.182

5.  Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases.

Authors:  R G Wells; M A Hediger
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-15       Impact factor: 11.205

6.  Expression cloning of a cDNA from rabbit kidney cortex that induces a single transport system for cystine and dibasic and neutral amino acids.

Authors:  J Bertran; A Werner; M L Moore; G Stange; D Markovich; J Biber; X Testar; A Zorzano; M Palacin; H Murer
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-15       Impact factor: 11.205

Review 7.  Structure and regulation of the MinK potassium channel.

Authors:  E M Blumenthal; L K Kaczmarek
Journal:  Neurochem Res       Date:  1992-09       Impact factor: 3.996

8.  Postural and locomotor control in normal and vestibularly deficient mice.

Authors:  P-P Vidal; L Degallaix; P Josset; J-P Gasc; K E Cullen
Journal:  J Physiol       Date:  2004-07-08       Impact factor: 5.182

9.  Functional expression of the amiloride-sensitive sodium channel in Xenopus oocytes.

Authors:  A L George; O Staub; K Geering; B C Rossier; T R Kleyman; J P Kraehenbuhl
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205

10.  Protein kinase C consensus sites and the regulation of renal Na/Pi-cotransport (NaPi-2) expressed in XENOPUS laevis oocytes.

Authors:  G Hayes; A E Busch; F Lang; J Biber; H Murer
Journal:  Pflugers Arch       Date:  1995-09       Impact factor: 3.657

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