| Literature DB >> 3194754 |
T Takumi1, H Ohkubo, S Nakanishi.
Abstract
A rat kidney messenger RNA that induces a slowly activating, voltage-dependent potassium current on its expression in Xenopus oocytes was identified by combining molecular cloning with an electrophysiological assay. The cloned complementary DNA encodes a novel membrane protein that consists of 130 amino acids with a single putative transmembrane domain. This protein differs from the known ion channel proteins but is involved in the induction of selective permeation of potassium ions by membrane depolarization.Entities:
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Year: 1988 PMID: 3194754 DOI: 10.1126/science.3194754
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728