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Literature DB >> 31933065

NIA workshop on senescence in brain aging and Alzheimer's disease and its related dementias.

Amanda M DiBattista¹, Felipe Sierra², Eliezer Masliah³.

Abstract

Entities: Disease

Year: 2020 PMID： 31933065 PMCID： PMC7206469 DOI： 10.1007/s11357-020-00153-9

Source DB: PubMed Journal: Geroscience ISSN： 2509-2723 Impact factor: 7.713

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7 in total

1. The serial cultivation of human diploid cell strains.

Authors: L HAYFLICK; P S MOORHEAD
Journal: Exp Cell Res Date: 1961-12 Impact factor: 3.905

Review 2. Unknown fates of (brain) oxidation or UFO: Close encounters with neuronal senescence.

Authors: Chaska C Walton; Julie K Andersen
Journal: Free Radic Biol Med Date: 2019-01-09 Impact factor: 7.376

3. Senolytic therapies for healthy longevity.

Authors: Jan M van Deursen
Journal: Science Date: 2019-05-17 Impact factor: 47.728

4. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model.

Authors: Peisu Zhang; Yuki Kishimoto; Ioannis Grammatikakis; Kamalvishnu Gottimukkala; Roy G Cutler; Shiliang Zhang; Kotb Abdelmohsen; Vilhelm A Bohr; Jyoti Misra Sen; Myriam Gorospe; Mark P Mattson
Journal: Nat Neurosci Date: 2019-04-01 Impact factor: 24.884

5. Tau protein aggregation is associated with cellular senescence in the brain.

Authors: Nicolas Musi; Joseph M Valentine; Kathryn R Sickora; Eric Baeuerle; Cody S Thompson; Qiang Shen; Miranda E Orr
Journal: Aging Cell Date: 2018-10-11 Impact factor: 9.304

6. Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.

Authors: Tyler J Bussian; Asef Aziz; Charlton F Meyer; Barbara L Swenson; Jan M van Deursen; Darren J Baker
Journal: Nature Date: 2018-09-19 Impact factor: 49.962

7. Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age.

Authors: Melod Mehdipour; Jessy Etienne; Chia-Chien Chen; Ranveer Gathwala; Maryam Rehman; Cameron Kato; Chao Liu; Yutong Liu; Yi Zuo; Michael J Conboy; Irina M Conboy
Journal: Aging (Albany NY) Date: 2019-08-15 Impact factor: 5.682

7 in total

1. Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer's Disease.

Authors: Sandra Espinoza; Felipe Grunenwald; Wileidy Gomez; Felipe García; Lorena Abarzúa-Catalan; Sebastián Oyarce-Pezoa; Maria Fernanda Hernandez; Bastián I Cortés; Markus Uhrig; Daniela P Ponce; Claudia Durán-Aniotz; Claudio Hetz; Carol D SanMartín; Victor H Cornejo; Fernando Ezquer; Valentina Parra; Maria Isabel Behrens; Patricio A Manque; Diego Rojas-Rivera; René L Vidal; Ute Woehlbier; Melissa Nassif
Journal: Cells Date: 2022-06-07 Impact factor: 7.666

7. High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture.

Authors: Jingang Hou; Byeongmin Jeon; Jongin Baek; Yeejin Yun; Daeun Kim; Boyoon Chang; Sungyeon Kim; Sunchang Kim
Journal: J Ginseng Res Date: 2021-04-16 Impact factor: 6.060

7 in total

NIA workshop on senescence in brain aging and Alzheimer's disease and its related dementias.

1. The serial cultivation of human diploid cell strains.

Review 2. Unknown fates of (brain) oxidation or UFO: Close encounters with neuronal senescence.

3. Senolytic therapies for healthy longevity.

4. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model.

5. Tau protein aggregation is associated with cellular senescence in the brain.

6. Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.

7. Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age.

1. Neuronal Rubicon Represses Extracellular APP/Amyloid β Deposition in Alzheimer's Disease.

2. Brain cellular senescence in mouse models of Alzheimer's disease.

Review 3. A geroscience motivated approach to treat Alzheimer's disease: Senolytics move to clinical trials.

4. Increase in blood-brain barrier leakage in healthy, older adults.

5. Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial.

Review 6. Residual Disease in Glioma Recurrence: A Dangerous Liaison with Senescence.

7. High fat diet-induced brain damaging effects through autophagy-mediated senescence, inflammation and apoptosis mitigated by ginsenoside F1-enhanced mixture.