Literature DB >> 31931266

The Rapidly Changing US Illicit Drug Market and the Potential for an Improved Early Warning System: Evidence from Ohio Drug Crime Labs.

Daniel Rosenblum1, Jay Unick2, Daniel Ciccarone3.   

Abstract

BACKGROUND: The US has seen a rapid increase in synthetic opioid-related overdose deaths. We investigate Ohio, a state with one of the highest overdose death rates in 2017 and substantial numbers of deaths related to fentanyl, carfentanil, and other fentanyl analogs, to provide detailed evidence about the relationship between changes in the illicit drug market and overdose deaths.
METHODS: We investigate the illicit drug market using Ohio's Bureau of Criminal Investigation's (BCI) crime lab data from 2009 to 2018 that shows the content of drugs seized by law enforcement. We use Poisson regression analysis to estimate the relationship between monthly crime lab data and monthly unintentional drug overdose death data at the county level.
RESULTS: During this time period there has been a rapid change in the composition of drugs analyzed by the BCI labs, with a rapid fall in heroin observations, simultaneous rise in synthetic opioids, and an increase in the number of different fentanyl analogs. We find that the increased presence of fentanyl, carfentanil, and other fentanyl analogs have a strong correlation with an increase in overdose deaths. The types of opioids most associated with deaths varies by the population size of the county.
CONCLUSIONS: Crime lab data has the potential to be used as an early warning system to alert persons who inject drugs, harm reduction services, first responders, and law enforcement about changes in the illicit opioid risk environment.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Carfentanil; Fentanyl; Fentanyl Analogs; Ohio; Overdose Deaths

Mesh:

Substances:

Year:  2020        PMID: 31931266      PMCID: PMC7096152          DOI: 10.1016/j.drugalcdep.2019.107779

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  17 in total

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Authors:  Sarah G Mars; Daniel Rosenblum; Daniel Ciccarone
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2.  Fentanyl in the US heroin supply: A rapidly changing risk environment.

Authors:  Daniel Ciccarone
Journal:  Int J Drug Policy       Date:  2017-07-20

3.  Heroin uncertainties: Exploring users' perceptions of fentanyl-adulterated and -substituted 'heroin'.

Authors:  Daniel Ciccarone; Jeff Ondocsin; Sarah G Mars
Journal:  Int J Drug Policy       Date:  2017-07-18

4.  Designer drugs: past history and future prospects.

Authors:  G L Henderson
Journal:  J Forensic Sci       Date:  1988-03       Impact factor: 1.832

5.  Development of a Statewide, Publicly Accessible Drug Overdose Surveillance and Information System.

Authors:  Brandon D L Marshall; Jesse L Yedinak; Jonathan Goyer; Traci C Green; Jennifer A Koziol; Nicole Alexander-Scott
Journal:  Am J Public Health       Date:  2017-09-21       Impact factor: 9.308

6.  Sold as Heroin: Perceptions and Use of an Evolving Drug in Baltimore, MD.

Authors:  Sarah G Mars; Jeff Ondocsin; Daniel Ciccarone
Journal:  J Psychoactive Drugs       Date:  2017-12-06

7.  The entry of Colombian-sourced heroin into the US market: the relationship between competition, price, and purity.

Authors:  Daniel Rosenblum; George Jay Unick; Daniel Ciccarone
Journal:  Int J Drug Policy       Date:  2013-10-19

8.  Fentanyl test strips as an opioid overdose prevention strategy: Findings from a syringe services program in the Southeastern United States.

Authors:  Nicholas C Peiper; Sarah Duhart Clarke; Louise B Vincent; Dan Ciccarone; Alex H Kral; Jon E Zibbell
Journal:  Int J Drug Policy       Date:  2018-10-03

9.  Toots, tastes and tester shots: user accounts of drug sampling methods for gauging heroin potency.

Authors:  Sarah G Mars; Jeff Ondocsin; Daniel Ciccarone
Journal:  Harm Reduct J       Date:  2018-05-16

10.  Drug and Opioid-Involved Overdose Deaths - United States, 2013-2017.

Authors:  Lawrence Scholl; Puja Seth; Mbabazi Kariisa; Nana Wilson; Grant Baldwin
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2018-01-04       Impact factor: 17.586

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  13 in total

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Authors:  Joseph J Palamar; Linda B Cottler; Bruce A Goldberger; Stevan Geoffrey Severtson; David J Grundy; Janetta L Iwanicki; Daniel Ciccarone
Journal:  Am J Drug Alcohol Abuse       Date:  2022-06-15       Impact factor: 3.912

2.  Trends in seizures of powders and pills containing illicit fentanyl in the United States, 2018 through 2021.

Authors:  Joseph J Palamar; Daniel Ciccarone; Caroline Rutherford; Katherine M Keyes; Thomas H Carr; Linda B Cottler
Journal:  Drug Alcohol Depend       Date:  2022-03-31       Impact factor: 4.852

3.  Fatal overdose: Predicting to prevent.

Authors:  Annick Borquez; Natasha K Martin
Journal:  Int J Drug Policy       Date:  2022-05-09

4.  Listed for sale: Analyzing data on fentanyl, fentanyl analogs and other novel synthetic opioids on one cryptomarket.

Authors:  Francois R Lamy; Raminta Daniulaityte; Monica J Barratt; Usha Lokala; Amit Sheth; Robert G Carlson
Journal:  Drug Alcohol Depend       Date:  2020-06-12       Impact factor: 4.492

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Authors:  Daniel Ciccarone
Journal:  Curr Opin Psychiatry       Date:  2021-07-01       Impact factor: 4.787

6.  The Evolving Overdose Epidemic: Synthetic Opioids and Rising Stimulant-Related Harms.

Authors:  Christopher M Jones; Faraah Bekheet; Ju Nyeong Park; G Caleb Alexander
Journal:  Epidemiol Rev       Date:  2020-01-31       Impact factor: 4.280

7.  Patterns of Routes of Administration and Drug Tampering for Nonmedical Opioid Consumption: Data Mining and Content Analysis of Reddit Discussions.

Authors:  Duilio Balsamo; Paolo Bajardi; Alberto Salomone; Rossano Schifanella
Journal:  J Med Internet Res       Date:  2021-01-04       Impact factor: 5.428

8.  Benzodiazepines reported in NFLIS-Drug, 2015 to 2018.

Authors:  Katherine Bollinger; BeLinda Weimer; David Heller; Nichole Bynum; Megan Grabenauer; DeMia Pressley; Hope Smiley-McDonald
Journal:  Forensic Sci Int       Date:  2021-02-09       Impact factor: 2.395

9.  Identifying counties at risk of high overdose mortality burden during the emerging fentanyl epidemic in the USA: a predictive statistical modelling study.

Authors:  Charles Marks; Daniela Abramovitz; Christl A Donnelly; Gabriel Carrasco-Escobar; Rocío Carrasco-Hernández; Daniel Ciccarone; Arturo González-Izquierdo; Natasha K Martin; Steffanie A Strathdee; Davey M Smith; Annick Bórquez
Journal:  Lancet Public Health       Date:  2021-06-10

10.  Carfentanil and the rise and fall of overdose deaths in the United States.

Authors:  Hawre Jalal; Donald S Burke
Journal:  Addiction       Date:  2020-09-25       Impact factor: 7.256

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