Literature DB >> 31926361

Implications of Drug Use Disorders on Spine Surgery.

Christopher S Ferari1, Gennadiy A Katsevman2, Patricia Dekeseredy3, Cara L Sedney3.   

Abstract

BACKGROUND: The opioid crisis has been declared a "public health emergency." Spine surgeons are treating more patients with substance use disorders (SUDs).
OBJECTIVE: To investigate the outcomes of patients with SUD who undergo spine surgery.
METHODS: A retrospective chart review was performed on patients with SUD who underwent nonelective spine surgery by orthopedic or neurosurgical staff from 2012 to 2017 at a level 1 trauma center and spine referral center. Three elective cases were excluded.
RESULTS: A total of 49 patients undergoing 72 surgeries were reviewed. The most common substances of abuse were opioids (44/49 patients; 90%). Of 31 patients using multisubstances (63%), 29 misused opioids. The most common indications for surgery were infection (26/49, 53%), trauma (13/49, 27%), and myelopathy (7/49, 14%). Fusions (35/49, 71%) and irrigation and debridement surgeries (12/49, 24%) predominated. Twenty-nine percent (14/49) of patients had complications, the most common being hardware failure (7/49, 14%). Twenty percent (10/49) of patients left against medical advice and 22% (11/49) did not follow up after hospital discharge. The average length of hospital stay was 22 days. Forty-five percent (22/49) of patients were known to be in a drug program preoperatively versus 39% (19/49) postoperatively. Sixty-five percent (32/49) were prescribed opioids in the immediate postoperative period and 47% (23/49) continued to abuse drugs postoperatively.
CONCLUSIONS: Patients with SUD are at increased risk of complications and inadequate follow-up. Additional studies are warranted to determine whether additional perioperative education, psychiatry consultations, or prescription of opioid addiction treatment regimens will improve drug use cessation and outcomes.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Patient outcomes; Spine surgery; Substance use disorder

Mesh:

Year:  2020        PMID: 31926361      PMCID: PMC7556334          DOI: 10.1016/j.wneu.2019.12.177

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  49 in total

1.  Leaving against medical advice (AMA): risk of 30-day mortality and hospital readmission.

Authors:  Justin M Glasgow; Mary Vaughn-Sarrazin; Peter J Kaboli
Journal:  J Gen Intern Med       Date:  2010-04-28       Impact factor: 5.128

Review 2.  Acute infections in intravenous drug users.

Authors:  Thomas W Lavender; Brendan McCarron
Journal:  Clin Med (Lond)       Date:  2013-10       Impact factor: 2.659

3.  Predictors of In-hospital Adverse Events in Patients with Prosthetic Valve Infective Endocarditis.

Authors:  Hwee-Leong Tan; Louis Y A Chai; Tiong-Cheng Yeo; Boon-Lock Chia; Paul A Tambyah; Kian-Keong Poh
Journal:  Heart Lung Circ       Date:  2015-02-16       Impact factor: 2.975

4.  The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States.

Authors:  Ali H Mokdad; Katherine Ballestros; Michelle Echko; Scott Glenn; Helen E Olsen; Erin Mullany; Alex Lee; Abdur Rahman Khan; Alireza Ahmadi; Alize J Ferrari; Amir Kasaeian; Andrea Werdecker; Austin Carter; Ben Zipkin; Benn Sartorius; Berrin Serdar; Bryan L Sykes; Chris Troeger; Christina Fitzmaurice; Colin D Rehm; Damian Santomauro; Daniel Kim; Danny Colombara; David C Schwebel; Derrick Tsoi; Dhaval Kolte; Elaine Nsoesie; Emma Nichols; Eyal Oren; Fiona J Charlson; George C Patton; Gregory A Roth; H Dean Hosgood; Harvey A Whiteford; Hmwe Kyu; Holly E Erskine; Hsiang Huang; Ira Martopullo; Jasvinder A Singh; Jean B Nachega; Juan R Sanabria; Kaja Abbas; Kanyin Ong; Karen Tabb; Kristopher J Krohn; Leslie Cornaby; Louisa Degenhardt; Mark Moses; Maryam Farvid; Max Griswold; Michael Criqui; Michelle Bell; Minh Nguyen; Mitch Wallin; Mojde Mirarefin; Mostafa Qorbani; Mustafa Younis; Nancy Fullman; Patrick Liu; Paul Briant; Philimon Gona; Rasmus Havmoller; Ricky Leung; Ruth Kimokoti; Shahrzad Bazargan-Hejazi; Simon I Hay; Simon Yadgir; Stan Biryukov; Stein Emil Vollset; Tahiya Alam; Tahvi Frank; Talha Farid; Ted Miller; Theo Vos; Till Bärnighausen; Tsegaye Telwelde Gebrehiwot; Yuichiro Yano; Ziyad Al-Aly; Alem Mehari; Alexis Handal; Amit Kandel; Ben Anderson; Brian Biroscak; Dariush Mozaffarian; E Ray Dorsey; Eric L Ding; Eun-Kee Park; Gregory Wagner; Guoqing Hu; Honglei Chen; Jacob E Sunshine; Jagdish Khubchandani; Janet Leasher; Janni Leung; Joshua Salomon; Jurgen Unutzer; Leah Cahill; Leslie Cooper; Masako Horino; Michael Brauer; Nicholas Breitborde; Peter Hotez; Roman Topor-Madry; Samir Soneji; Saverio Stranges; Spencer James; Stephen Amrock; Sudha Jayaraman; Tejas Patel; Tomi Akinyemiju; Vegard Skirbekk; Yohannes Kinfu; Zulfiqar Bhutta; Jost B Jonas; Christopher J L Murray
Journal:  JAMA       Date:  2018-04-10       Impact factor: 56.272

Review 5.  The Effect of Opioids, Alcohol, and Nonsteroidal Anti-inflammatory Drugs on Fracture Union.

Authors:  Christopher J Richards; Kenneth W Graf; Rakesh P Mashru
Journal:  Orthop Clin North Am       Date:  2017-07-29       Impact factor: 2.472

6.  Risk of Pseudoarthrosis After Spinal Fusion: Analysis From the Healthcare Cost and Utilization Project.

Authors:  Ryan C Hofler; Kevin Swong; Brendan Martin; Michael Wemhoff; George Alexander Jones
Journal:  World Neurosurg       Date:  2018-08-13       Impact factor: 2.104

7.  Conversion of chronic pain patients from full-opioid agonists to sublingual buprenorphine.

Authors:  Jonathan Daitch; Michael E Frey; David Silver; Carol Mitnick; Danielle Daitch; Joseph Pergolizzi
Journal:  Pain Physician       Date:  2012-07       Impact factor: 4.965

8.  Chronic opioid use is a risk factor for the development of central sleep apnea and ataxic breathing.

Authors:  James M Walker; Robert J Farney; Steven M Rhondeau; Kathleen M Boyle; Karen Valentine; Tom V Cloward; Kevin C Shilling
Journal:  J Clin Sleep Med       Date:  2007-08-15       Impact factor: 4.062

9.  Prevalence of opioid dependence in spine surgery patients and correlation with length of stay.

Authors:  Mohammad Sami Walid; Leon Hyer; Mohammed Ajjan; Aaron C M Barth; Joe Sam Robinson
Journal:  J Opioid Manag       Date:  2007 May-Jun

10.  Hypogonadism in men receiving methadone and buprenorphine maintenance treatment.

Authors:  R Hallinan; A Byrne; K Agho; C G McMahon; P Tynan; J Attia
Journal:  Int J Androl       Date:  2007-10-30
View more
  3 in total

Review 1.  Review of Neurologic Comorbidities in Hospitalized Patients With Opioid Abuse.

Authors:  Kevin R Nelson; Katelyn Dolbec; William Watson; Hanwen Yuan; Mam Ibraheem
Journal:  Neurol Clin Pract       Date:  2021-12

Review 2.  Stigmatizing Diagnoses in Neurosurgery: A Narrative Review.

Authors:  Cara L Sedney; Patricia Dekeseredy; Treah Haggerty
Journal:  World Neurosurg       Date:  2020-09-02       Impact factor: 2.104

3.  The influence of modifiable risk factors on short-term postoperative outcomes following cervical spine surgery: A retrospective propensity score matched analysis.

Authors:  Shane Shahrestani; Joshua Bakhsheshian; Xiao T Chen; Andy Ton; Alexander M Ballatori; Ben A Strickland; Djani M Robertson; Zorica Buser; Raymond Hah; Patrick C Hsieh; John C Liu; Jeffrey C Wang
Journal:  EClinicalMedicine       Date:  2021-05-15
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.