Literature DB >> 31924389

Product dose considerations for real-world hand sanitiser efficacy.

N Kenters1, A Eikelenboom-Boskamp2, J Hines3, A McGeer4, E G W Huijskens5, A Voss6.   

Abstract

BACKGROUND: Alcohol based hand rubs (ABHR) are extremely effective at reducing microbial contamination and have an essential role in best practice hand hygiene described by the World Health Organization.
METHODS: We determined ABHR drying time when performing hand hygiene in a laboratory setting. Which was followed by identifying the amount of ABHR needed for complete hand coverage. When the aforementioned was analyzed real-time data were gathered to examine the amount used for hand hygiene in a hospital setting. In parallel hands of healthcare workers (HCWs) were monitored for drying time and perception on ABHR use.
RESULTS: In 86% (24,446,397/28,280,383) of the events a single dose of ABHR was used on clinical wards. Twenty-four HCWs expected hand hygiene to take 7.5 seconds (median; range 3-30 seconds). Forty-three HCWs show that 1.5 mL ABHR dose achieves the desired drying time according to World Health Organization guidelines (av. median 26 seconds), but is consistently perceived to have a longer drying time than expected (av. median 18 seconds). In-vivo results (n = 10) indicate that 2.25 mL ABHR is required for adequate coverage (82%-90%) of both sides of the hand.
CONCLUSIONS: Results indicate that set standards for the use of ABHR do not match "in-vivo" behaviour of HCWs. Perceived drying times are shorter than actual drying time. The needed drying time to reach acceptable antimicrobial efficacy of ABHRs should be revisited.
Copyright © 2019 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  ABHR; Hand hygiene; Product dose; Product volume

Mesh:

Substances:

Year:  2020        PMID: 31924389     DOI: 10.1016/j.ajic.2019.12.001

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN: 0196-6553            Impact factor:   2.918


  5 in total

Review 1.  Sailing through the COVID-19 Pandemic and Beyond: An Evidence-Based Analysis for Dental Healthcare and Practice.

Authors:  Harpreet Singh; Shabina Sachdeva; Dhirendra Srivastava; Pranav Kapoor; Poonam Sharma; Raj Kumar Maurya; Pinaki Roy
Journal:  Front Dent       Date:  2022-03-07

Review 2.  Alcohol-based hand sanitizer - composition, proper use and precautions.

Authors:  Tushar Saha; Prakash Khadka; Shyamal C Das
Journal:  Germs       Date:  2021-09-29

3.  Systematic review on factors influencing the effectiveness of alcohol-based hand rubbing in healthcare.

Authors:  Lesley Price; Lucyna Gozdzielewska; Julius Cesar Alejandre; Annelysse Jorgenson; Emma Stewart; Didier Pittet; Jacqui Reilly
Journal:  Antimicrob Resist Infect Control       Date:  2022-01-24       Impact factor: 4.887

4.  Adult and children's use of hand sanitizer during a pandemic - an observational study.

Authors:  Theresa K Lopez; Kelly Jones; Ann Roseberry-Lincoln; Angelika Zidek; Leona MacKinnon; Leonora Marro
Journal:  J Expo Sci Environ Epidemiol       Date:  2022-09-24       Impact factor: 6.371

5.  A large-scale investigation of alcohol-based handrub (ABHR) volume: hand coverage correlations utilizing an innovative quantitative evaluation system.

Authors:  Constantinos Voniatis; Száva Bánsághi; Andrea Ferencz; Tamás Haidegger
Journal:  Antimicrob Resist Infect Control       Date:  2021-03-07       Impact factor: 4.887

  5 in total

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