Jean F Wyman1, Jincheng Zhou2, D Yvette LaCoursiere3, Alayne D Markland4, Elizabeth R Mueller5, Laura Simon6, Ann Stapleton7, Carolyn R T Stoll8, Haitao Chu2, Siobhan Sutcliffe8. 1. School of Nursing, University of Minnesota, Minneapolis, Minnesota. 2. Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota. 3. Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, LaJolla, California. 4. Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, Birmingham/Atlanta Geriatrics Research, Education, and Clinical Center, University of Alabama at Birmingham, Birmingham, Alabama. 5. Departments of Urology and Obstetrics/Gynecology, Loyola University Medical Center, Loyola University Chicago, Maywood, Illinois. 6. Bernard Becker Medical Library, Washington University in St. Louis, St. Louis, Missouri. 7. Department of Medicine, University of Washington, Seattle, Washington. 8. Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis, St. Louis, Missouri.
Abstract
AIM: To conduct an evidence synthesis of normative reference values for bladder function parameters in women. METHODS: We conducted a systematic review and meta-analysis of studies reporting bladder function parameters obtained from noninvasive tests in healthy women. Seven databases were searched for relevant studies from inception through December 2018, with manual searching of reference lists. We included English language articles that provided quantitative data on urination frequency, voided and postvoid residual volumes, and uroflowmetry results in women without lower urinary tract symptoms. Study selection, data extraction, and quality assessment were undertaken by at least two independent reviewers. Random-effects meta-analytic models were used to derive study-level pooled mean estimates and 95% confidence intervals. RESULTS: A total of 24 studies (N = 3090 women, age range, 18-91 years) met eligibility criteria. Pooled mean estimates of bladder function parameters were: 6.6 daytime voids (95% confidence interval (95% CI), 6.2, 7.0), 0.4 nighttime voids (95% CI, 0.0, 0.8), 1577 mL for 24-hour voided volume (95% CI 1428,1725); 12 mL for postvoid residual volume (95% CI, 4, 20); and 28 mL/sec for maximum flow rate (95% CI, 27,30). Between-study heterogeneity was high for all outcomes (I2 = 61.1-99.6%), but insufficient data were available to explore reasons for this high heterogeneity (eg, differences by age). CONCLUSION: Although summary mean estimates of bladder function parameters were calculated, the wide heterogeneity across studies precludes generalization of these estimates to all healthy women. Further research is needed to determine normative reference values within specific groups, such as those defined by age.
AIM: To conduct an evidence synthesis of normative reference values for bladder function parameters in women. METHODS: We conducted a systematic review and meta-analysis of studies reporting bladder function parameters obtained from noninvasive tests in healthy women. Seven databases were searched for relevant studies from inception through December 2018, with manual searching of reference lists. We included English language articles that provided quantitative data on urination frequency, voided and postvoid residual volumes, and uroflowmetry results in women without lower urinary tract symptoms. Study selection, data extraction, and quality assessment were undertaken by at least two independent reviewers. Random-effects meta-analytic models were used to derive study-level pooled mean estimates and 95% confidence intervals. RESULTS: A total of 24 studies (N = 3090 women, age range, 18-91 years) met eligibility criteria. Pooled mean estimates of bladder function parameters were: 6.6 daytime voids (95% confidence interval (95% CI), 6.2, 7.0), 0.4 nighttime voids (95% CI, 0.0, 0.8), 1577 mL for 24-hour voided volume (95% CI 1428,1725); 12 mL for postvoid residual volume (95% CI, 4, 20); and 28 mL/sec for maximum flow rate (95% CI, 27,30). Between-study heterogeneity was high for all outcomes (I2 = 61.1-99.6%), but insufficient data were available to explore reasons for this high heterogeneity (eg, differences by age). CONCLUSION: Although summary mean estimates of bladder function parameters were calculated, the wide heterogeneity across studies precludes generalization of these estimates to all healthy women. Further research is needed to determine normative reference values within specific groups, such as those defined by age.
Authors: Matthew Parsons; William Tissot; Linda Cardozo; Ananias Diokno; Cindy L Amundsen; Alfred C Coats Journal: Neurourol Urodyn Date: 2007 Impact factor: 2.696
Authors: Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde Journal: J Biomed Inform Date: 2008-09-30 Impact factor: 6.317
Authors: Edward J Boyko; Stephan D Fihn; Delia Scholes; Chi-Ling Chen; Esther H Normand; Patricia Yarbro Journal: Diabetes Care Date: 2002-10 Impact factor: 19.112
Authors: Bernard L Harlow; Tamara G Bavendam; Mary H Palmer; Linda Brubaker; Kathryn L Burgio; Emily S Lukacz; Janis M Miller; Elizabeth R Mueller; Diane K Newman; Leslie M Rickey; Siobhan Sutcliffe; Denise Simons-Morton Journal: J Womens Health (Larchmt) Date: 2017-09-15 Impact factor: 2.681
Authors: Jean F Wyman; Charles H Cain; C Neill Epperson; Colleen M Fitzgerald; Sheila Gahagan; Diane K Newman; Kyle Rudser; Ariana L Smith; Camille P Vaughan; Siobhan Sutcliffe Journal: Nurs Res Date: 2022-03-22 Impact factor: 2.364
Authors: Ágnes Rita Martonosi; Piroska Pázmány; Szabolcs Kiss; Fanni Dembrovszky; Eduard Oštarijaš; László Szabó Journal: Med Sci Monit Date: 2022-07-09
Authors: Ariana L Smith; Leslie M Rickey; Sonya S Brady; Cynthia S Fok; Jerry L Lowder; Alayne D Markland; Elizabeth R Mueller; Siobhan Sutcliffe; Tamara G Bavendam; Linda Brubaker Journal: Urology Date: 2020-03-18 Impact factor: 2.649
Authors: Kathryn L Burgio; Aimee S James; D Yvette LaCoursiere; Elizabeth R Mueller; Diane K Newman; Lisa Kane Low; Kevin P Weinfurt; Jean F Wyman; Shayna D Cunningham; Keith Vargo; John Connett; Beverly Rosa Williams Journal: Urology Date: 2020-08-22 Impact factor: 2.649
Authors: Melanie R Meister; Jincheng Zhou; Haitao Chu; Tamera Coyne-Beasley; Sheila Gahagan; D Yvette LaCoursiere; Elizabeth R Mueller; Peter Scal; Laura Simon; Ann E Stapleton; Carolyn R T Stoll; Siobhan Sutcliffe; Amanda Berry; Jean F Wyman Journal: J Pediatr Urol Date: 2021-05-11 Impact factor: 1.921