| Literature DB >> 31916400 |
Isabella C Glitza1, Keiran S M Smalley2, Priscilla K Brastianos3, Michael A Davies1, Ian McCutcheon4, James K C Liu5, Kamran A Ahmed6, John A Arrington7, Brittany R Evernden5, Inna Smalley8, Zeynep Eroglu9, Nikhil Khushalani9, Kim Margolin10, Harriet Kluger11, Michael B Atkins12, Hussein Tawbi1, Adrienne Boire13, Peter Forsyth5.
Abstract
In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System Metastases in Tampa, Florida. The meeting included investigators from multiple academic centers and disciplines. A consensus summary of the progress and challenges in melanoma parenchymal brain metastases was published (Eroglu et al., Pigment Cell & Melanoma Research, 2019, 32, 458). Here, we will describe the current state of basic, translational, clinical research, and therapeutic management, for melanoma patients with leptomeningeal disease. We also outline key challenges and barriers to be overcome to make progress in this deadly disease.Entities:
Keywords: intrathecal therapy; leptomeningeal carcinomatosis; leptomeningeal disease; melanoma; neoplastic meningitis
Year: 2020 PMID： 31916400 DOI： 10.1111/pcmr.12861
Source DB: PubMed Journal: Pigment Cell Melanoma Res ISSN： 1755-1471 Impact factor: 4.693