Literature DB >> 31904700

The HIV Pre-exposure Prophylaxis (PrEP) Cascade at NYC Sexual Health Clinics: Navigation Is the Key to Uptake.

Preeti Pathela1, Kelly Jamison1, Susan Blank1,2, Demetre Daskalakis1, Trevor Hedberg1, Christine Borges1.   

Abstract

BACKGROUND: Clinics providing sexual health care pose unique opportunities to implement HIV pre-exposure prophylaxis (PrEP) programs. The PrEP program at New York City's Sexual Health Clinics provides intensive on-site navigation for linkage to PrEP care. We assessed uptake of this intervention.
METHODS: We categorized men who have sex with men (MSM) without HIV hierarchically as having had (1) HIV post-exposure prophylaxis (PEP) use (past year); or (2) selected sexually transmitted infections (STI) (past year); or (3) HIV-diagnosed sex/needle-sharing partners (past 6 months); or (4) expressed interest in PrEP (day of clinic visit). We constructed PrEP cascades and used multivariable regression to examine acceptance of PrEP navigation, referral to a PrEP provider, linkage (<60 days), and PrEP prescription.
RESULTS: One thousand three hundred one of 2106 PrEP (62%) patients accepted navigation. Of those, 55% (718/1301) were black or Hispanic MSM. STI and PEP patients had lowest navigation acceptance levels (35%-46%). Of navigated patients, 56% (628/1114) accepted referrals, 46% (288/628) linked to PrEP providers, and 82% (235/288) were prescribed PrEP; overall, 11% of those offered navigation (235/2106) received prescriptions. Navigated MSM with PEP history [adjusted prevalence ratio (aPR) 1.34, 95% confidence interval (CI): 1.16 to 1.56)], previous STI (aPR 1.28, 95% CI: 1.12 to 1.45), or HIV-diagnosed partners (aPR 1.18, 95% CI: 1.01 to 1.37) were more likely than those with PrEP interest to accept referrals. Probability of linkage varied by insurance status; prescription did not vary by patient factors.
CONCLUSIONS: Although MSM in key priority groups (eg, previous STI) showed low navigation uptake, those who accepted navigation were likely to be referred for PrEP, suggesting a need for expanded up-front engagement.

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Year:  2020        PMID: 31904700     DOI: 10.1097/QAI.0000000000002274

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.731


  21 in total

Review 1.  Confronting Rising STIs in the Era of PrEP and Treatment as Prevention.

Authors:  Meena S Ramchandani; Matthew R Golden
Journal:  Curr HIV/AIDS Rep       Date:  2019-06       Impact factor: 5.071

2.  What Will It Take to End HIV in the United States? : A Comprehensive, Local-Level Modeling Study.

Authors:  Anthony Todd Fojo; Melissa Schnure; Parastu Kasaie; David W Dowdy; Maunank Shah
Journal:  Ann Intern Med       Date:  2021-09-21       Impact factor: 25.391

3.  The effect of an HIV preexposure prophylaxis panel management strategy to increase preexposure prophylaxis prescriptions.

Authors:  Parya Saberi; Marie C D Stoner; Kristin Ming; Nadra E Lisha; J Carlo Hojilla; Hyman M Scott; Albert Y Liu; Wayne T Steward; Mallory O Johnson; Torsten B Neilands
Journal:  AIDS       Date:  2022-06-22       Impact factor: 4.632

4.  'PrEP'ing Memphis: A qualitative process evaluation of peer navigation support.

Authors:  Latrice C Pichon; Michelle Teti; Joshua E Betts; Meredith Brantley
Journal:  Eval Program Plann       Date:  2021-08-13

5.  Evaluation of an HIV Pre-Exposure Prophylaxis Referral System: From Sexual Health Center to Federally Qualified Health Center Pre-Exposure Prophylaxis Clinic.

Authors:  Rebecca Lillis; Jeremy Beckford; Joshua Fegley; Julia Siren; Bruce Hinton; Samuel Gomez; Stephanie N Taylor; Isolde Butler; Jason Halperin; Meredith Edwards Clement
Journal:  AIDS Patient Care STDS       Date:  2021-08-26       Impact factor: 5.944

6.  What Predicts a Clinical Discussion About PrEP? Results From Analysis of a U.S. National Cohort of HIV-Vulnerable Sexual and Gender Minorities.

Authors:  Pedro B Carneiro; Victoria Frye; Chloe Mirzayi; Viraj Patel; David Lounsbury; Terry T-K Huang; Nasim Sabounchi; Christian Grov
Journal:  AIDS Educ Prev       Date:  2022-06

7.  Lessons Learned from an HIV Pre-Exposure Prophylaxis Coordination Program in San Francisco Primary Care Clinics.

Authors:  Isha Shrestha; Kristin Ming; Veronica Jimenez; James Wendelborn; Alexander Vazquez; Wayne Steward; Hyman Scott; Parya Saberi
Journal:  AIDS Res Hum Retroviruses       Date:  2022-06-16       Impact factor: 1.723

8.  Geographic Disparities in Availability of Spanish-Language PrEP Services Among Latino Sexual Minority Men in South Florida.

Authors:  Cho-Hee Shrader; Justin Stoler; Juan Arroyo-Flores; Susanne Doblecki-Lewis; Adam Carrico; Steven Safren; Stephen Fallon; Mariano Kanamori
Journal:  J Immigr Minor Health       Date:  2022-10-20

9.  Five Waves of an Online HIV Self-Test Giveaway in New York City, 2015 to 2018.

Authors:  Zoe R Edelstein; Amanda Wahnich; Lawrence J Purpura; Paul M Salcuni; Benjamin W Tsoi; Paul H Kobrak; Paul A Santos; Adriana Andaluz; Jennifer H MacGregor; Jennifer D M Matsuki; David A Katz; Demetre C Daskalakis; Julie E Myers
Journal:  Sex Transm Dis       Date:  2020-05       Impact factor: 2.830

10.  Reaching Those Most at Risk for HIV Acquisition: Evaluating Racial/Ethnic Disparities in the Preexposure Prophylaxis Care Continuum in Baltimore City, Maryland.

Authors:  Christina M Schumacher; Xueting Tao; Aruna Chandran; Errol Fields; Ashley Price; Adena Greenbaum; Jacky M Jennings
Journal:  J Acquir Immune Defic Syndr       Date:  2021-08-15       Impact factor: 3.771

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