F Braido1,2, I Baiardini3, M Ferrando1, N Scichilone4, P Santus5, A Petrone6, F Di Marco7, A G Corsico8, A Zanforlin9, M Milanese10, G Steinhilber11, M Bonavia12, P Pirina13, C Micheletto14, M D'Amato15, D Lacedonia16, F Benassi17, A Propati18, P Ruggeri19, F Tursi20, M L Bocchino21, V Patella22,23, G W Canonica24, F Blasi25,26. 1. Dipartimento di Medicina Interna (DiMI), University of Genoa, Genoa, Italy. 2. IRCCS Ospedale Policlinico San Martino, Genoa, Italy. 3. Department of Biomedical Sciences, Humanitas University, Milan, Italy. 4. Scichilone N. PROMISE Department, AOUP University Hospital, University of Palermo, Palermo, Italy. 5. Biomedical and Clinical Sciences (DIBIC), Università degli Studi di Milano, Division of Respiratory Diseases, L. Sacco University Hospital, Milano, Italy. 6. UOC Pneumologia, Presidio Ospedaliero, Santa Barbaral, Rogliano, Italy. 7. Department of Health Sciences, Università degli Studi di Milano, Respiratory Unit, ASST Papa Giovanni XXIII Hospital, Bergamo, Italy. 8. Division of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation and Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy. 9. Medicina Interna, Ospedale di Bolzano, Bolzano, Italy. 10. SSD Pneumologia ASL2 Savonese, Ospedale S. Corona, Pietra Ligure, Italy. 11. Pneumology Unit, Spedali Civili di Brescia, Brescia, Italy. 12. Pneumologia, Ospedale La Colletta, Arenzano, Italy. 13. Respiratory Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy. 14. UOC di Pneumologia Azienda Ospedaliera Universitaria Integrata, Verona, Italy. 15. Malattie Respiratorie "Federico II"- AO "Dei Colli", Napoli, Italy. 16. Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy. 17. Dipartimento di Malattie Polmonari UOSD Insufficienza respiratoria e riabilitazione, Azienda Ospedaliera San Camillo Forlanini, Roma, Italy. 18. Unità Operativa Pneumologia, Ospedale C, Forlanini, Roma, Italy. 19. Unità Operativa Complessa di Pneumologia, Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Università degli Studi di Messina, Messina, Italy. 20. USS Servizio di pneumologia di Codogno, ASST di Lodi, Lodi, Italy. 21. UOC Pneumotisioligia, Dipartimento di Medicina Clinica e Chirurgia, Università degli Studi di Napoli Federico II, Naples, Italy. 22. Division of Respiratory Allergy, Santa Maria della Speranza Hospital, Salerno, Italy. 23. Postgraduate Program in Allergy and Clinical Immunology, University of Naples Federico II, Naples, Italy. 24. Personalized Medicine, Asthma and Allergy - Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy. 25. Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. 26. Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Italy.
Abstract
Background: Sleep is a significant dimension of daily life. However, only a few studies have examined the sleep quality of asthmatics in a real-world clinical settings.Objective: This study is aimed to estimate the prevalence of sleep impairments among asthmatic patients and examine the relationship between sleep quality, asthma control, rhinitis symptoms, and sociodemographic characteristics. Methods: The present study adopted the observational cross-sectional research design that has been designed by the Italian Respiratory Society and used valid assessments to measure the study variables. Results: Data from 1150 asthmatic patients (mean age 51.01 years ± 16.03) were subjected to analysis. 58.3% of the patients had impaired sleep quality (Pittsburgh Sleep Quality Index [PSQI] total scores > 5), and their mean PSQI score was 5.68 (SD = 3.4). A significant correlation emerged between sleep quality and asthma control (p = 0.0001) and a significant albeit weak correlation emerged between PSQI total scores and Total 5 Symptoms Score (r = 0.24, p = 0.0001). Sleep quality was significantly associated health-related quality of life [HRQoL]. (r = 0.50, p < 0.001). After exclusion of patients at risk for Obstructive Sleep Apnea Syndrome (OSAS) and Gastro Esophageal Reflux Disease (GERD), the most important determinants of PSQI score were HRQoL, In the entire sample asthma control is the strongest predictor of both sleep quality and HRQoL.Conclusions: The results of this real-world study highlight the prevalence, impact and predictors of sleep disturbances in asthmatic patients and suggest the need for physicians to detect poor sleep quality.
Background: Sleep is a significant dimension of daily life. However, only a few studies have examined the sleep quality of asthmatics in a real-world clinical settings.Objective: This study is aimed to estimate the prevalence of sleep impairments among asthmatic patients and examine the relationship between sleep quality, asthma control, rhinitis symptoms, and sociodemographic characteristics. Methods: The present study adopted the observational cross-sectional research design that has been designed by the Italian Respiratory Society and used valid assessments to measure the study variables. Results: Data from 1150 asthmatic patients (mean age 51.01 years ± 16.03) were subjected to analysis. 58.3% of the patients had impaired sleep quality (Pittsburgh Sleep Quality Index [PSQI] total scores > 5), and their mean PSQI score was 5.68 (SD = 3.4). A significant correlation emerged between sleep quality and asthma control (p = 0.0001) and a significant albeit weak correlation emerged between PSQI total scores and Total 5 Symptoms Score (r = 0.24, p = 0.0001). Sleep quality was significantly associated health-related quality of life [HRQoL]. (r = 0.50, p < 0.001). After exclusion of patients at risk for Obstructive Sleep Apnea Syndrome (OSAS) and Gastro Esophageal Reflux Disease (GERD), the most important determinants of PSQI score were HRQoL, In the entire sample asthma control is the strongest predictor of both sleep quality and HRQoL.Conclusions: The results of this real-world study highlight the prevalence, impact and predictors of sleep disturbances in asthmatic patients and suggest the need for physicians to detect poor sleep quality.
Entities:
Keywords:
Asthma; quality of life; reflux; rhinitis; sleep; sleepiness
Authors: Faith S Luyster; Xiaojun Shi; Lynn M Baniak; Jonna L Morris; Eileen R Chasens Journal: Ann Allergy Asthma Immunol Date: 2020-05-07 Impact factor: 6.347
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