Literature DB >> 31903081

The Developmental Origins of Health and Disease (DOHaD).

Salvatore Lacagnina1.   

Abstract

For years many have believed that genetic heritage defined one's destiny, if an individual would grow to be healthy, or if he or she would suffer from chronic illness or cancer. Recent scientific evidence and the field of epigenetics has proven this to be untrue. Certainly, the DNA sequence and the genetic code are fixed; but the field of epigenetics has shown how methylation and other chemical modifications of the genome directly influence the production of proteins that can alter the phenotype of an organism. This article will lay out the supporting research, the details on how the internal and external environments influence genetic function, and will allow the reader to develop an action plan necessary to influence the genetic code, with the goal of then moving the individual toward optimal health. These research details will enable health care professionals in every field of medicine to work with patients on positively influencing the genetic output in order to improve the quality of life and longevity.
© 2019 The Author(s).

Entities:  

Keywords:  DNA modification; epigenetics; genetic code; heredity

Year:  2019        PMID: 31903081      PMCID: PMC6933571          DOI: 10.1177/1559827619879694

Source DB:  PubMed          Journal:  Am J Lifestyle Med        ISSN: 1559-8276


  22 in total

1.  Mindfulness-based cancer recovery and supportive-expressive therapy maintain telomere length relative to controls in distressed breast cancer survivors.

Authors:  Linda E Carlson; Tara L Beattie; Janine Giese-Davis; Peter Faris; Rie Tamagawa; Laura J Fick; Erin S Degelman; Michael Speca
Journal:  Cancer       Date:  2014-11-03       Impact factor: 6.860

Review 2.  The developmental origins of well-being.

Authors:  D J P Barker
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-09-29       Impact factor: 6.237

Review 3.  Prenatal multivitamin supplementation and rates of congenital anomalies: a meta-analysis.

Authors:  Y Ingrid Goh; Enkelejd Bollano; Thomas R Einarson; Gideon Koren
Journal:  J Obstet Gynaecol Can       Date:  2006-08

Review 4.  Mechanisms affecting neuroendocrine and epigenetic regulation of body weight and onset of puberty: potential implications in the child born small for gestational age (SGA).

Authors:  Christian L Roth; Sheela Sathyanarayana
Journal:  Rev Endocr Metab Disord       Date:  2012-06       Impact factor: 6.514

5.  Persistent epigenetic differences associated with prenatal exposure to famine in humans.

Authors:  Bastiaan T Heijmans; Elmar W Tobi; Aryeh D Stein; Hein Putter; Gerard J Blauw; Ezra S Susser; P Eline Slagboom; L H Lumey
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-27       Impact factor: 11.205

6.  Predicting preschooler obesity at birth: the role of maternal obesity in early pregnancy.

Authors:  Robert C Whitaker
Journal:  Pediatrics       Date:  2004-07       Impact factor: 7.124

7.  Weight in infancy and prevalence of coronary heart disease in adult life.

Authors:  C H Fall; M Vijayakumar; D J Barker; C Osmond; S Duggleby
Journal:  BMJ       Date:  1995-01-07

8.  Protein intake and ovulatory infertility.

Authors:  Jorge E Chavarro; Janet W Rich-Edwards; Bernard A Rosner; Walter C Willett
Journal:  Am J Obstet Gynecol       Date:  2008-02       Impact factor: 8.661

Review 9.  Transgenerational developmental programming.

Authors:  Catherine E Aiken; Susan E Ozanne
Journal:  Hum Reprod Update       Date:  2013-09-29       Impact factor: 15.610

10.  In utero effects. In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism.

Authors:  Mitsuteru Ito; Hui Shi; Kazuki Yamazawa; Elvira Isganaitis; Elizabeth J Radford; Jennifer A Corish; Stefanie Seisenberger; Timothy A Hore; Wolf Reik; Serap Erkek; Antoine H F M Peters; Mary-Elizabeth Patti; Anne C Ferguson-Smith
Journal:  Science       Date:  2014-07-10       Impact factor: 47.728

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  4 in total

1.  Nutritionists' Practices and Knowledge about the Risks of Alcohol Consumption during Pregnancy: An Israeli Survey.

Authors:  Liat Hen-Herbst; Meital Ron El Levin; Yehuda Senecky; Sigal Frishman; Andrea Berger
Journal:  Nutrients       Date:  2022-04-29       Impact factor: 6.706

2.  Disruption of paternal circadian rhythm affects metabolic health in male offspring via nongerm cell factors.

Authors:  Maximilian Lassi; Archana Tomar; Gemma Comas-Armangué; Rebekka Vogtmann; Dorieke J Dijkstra; David Corujo; Raffaele Gerlini; Jonatan Darr; Fabienne Scheid; Jan Rozman; Antonio Aguilar-Pimentel; Omry Koren; Marcus Buschbeck; Helmut Fuchs; Susan Marschall; Valerie Gailus-Durner; Martin Hrabe de Angelis; Torsten Plösch; Alexandra Gellhaus; Raffaele Teperino
Journal:  Sci Adv       Date:  2021-05-26       Impact factor: 14.136

3.  Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats.

Authors:  Ferdinando Nicoletti; Stefania Maccari; Remy Verhaeghe; Vance Gao; Sara Morley-Fletcher; Hammou Bouwalerh; Gilles Van Camp; Francesca Cisani
Journal:  Geroscience       Date:  2021-05-13       Impact factor: 7.713

Review 4.  Taurine: A Maternally Derived Nutrient Linking Mother and Offspring.

Authors:  Shiro Tochitani
Journal:  Metabolites       Date:  2022-03-05
  4 in total

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