PURPOSE: To evaluate the use of magnetic resonance fingerprinting (MRF) for simultaneous quantification of T 1 and T 2 ∗ in a single breath-hold in the kidneys. METHODS: The proposed kidney MRF sequence was based on MRF echo-planar imaging. Thirty-five measurements per slice and overall 4 slices were measured in 15.4 seconds. Group matching was performed for in-line quantification of T 1 and T 2 ∗ . Images were acquired in a phantom and 8 healthy volunteers in coronal orientation. To evaluate our approach, region of interests were drawn in the kidneys to calculate mean values and standard deviations of the T 1 and T 2 ∗ times. Precision was calculated across multiple repeated MRF scans. Gaussian filtering is applied on baseline images to improve SNR and match stability. RESULTS: T 1 and T 2 ∗ times acquired with MRF in the phantom showed good agreement with reference measurements and conventional mapping methods with deviations of less than 5% for T 1 and less than 10% for T 2 ∗ . Baseline images in vivo were free of artifacts and relaxation times yielded good agreement with conventional methods and literature (deviation T 1 : 7 ± 4 % , T 2 ∗ : 6 ± 3 % ). CONCLUSIONS: In this feasibility study, the proposed renal MRF sequence resulted in accurate T 1 and T 2 ∗ quantification in a single breath-hold.
PURPOSE: To evaluate the use of magnetic resonance fingerprinting (MRF) for simultaneous quantification of T 1 and T 2 ∗ in a single breath-hold in the kidneys. METHODS: The proposed kidney MRF sequence was based on MRF echo-planar imaging. Thirty-five measurements per slice and overall 4 slices were measured in 15.4 seconds. Group matching was performed for in-line quantification of T 1 and T 2 ∗ . Images were acquired in a phantom and 8 healthy volunteers in coronal orientation. To evaluate our approach, region of interests were drawn in the kidneys to calculate mean values and standard deviations of the T 1 and T 2 ∗ times. Precision was calculated across multiple repeated MRF scans. Gaussian filtering is applied on baseline images to improve SNR and match stability. RESULTS: T 1 and T 2 ∗ times acquired with MRF in the phantom showed good agreement with reference measurements and conventional mapping methods with deviations of less than 5% for T 1 and less than 10% for T 2 ∗ . Baseline images in vivo were free of artifacts and relaxation times yielded good agreement with conventional methods and literature (deviation T 1 : 7 ± 4 % , T 2 ∗ : 6 ± 3 % ). CONCLUSIONS: In this feasibility study, the proposed renal MRF sequence resulted in accurate T 1 and T 2 ∗ quantification in a single breath-hold.
Authors: Mandi Wang; Jose A U Perucho; Peng Cao; Varut Vardhanabhuti; Di Cui; Yiang Wang; Pek-Lan Khong; Edward S Hui; Elaine Y P Lee Journal: Quant Imaging Med Surg Date: 2021-09
Authors: Azadeh Sharafi; Katherine Medina; Marcelo W V Zibetti; Smita Rao; Martijn A Cloos; Ryan Brown; Ravinder R Regatte Journal: Magn Reson Med Date: 2021-02-08 Impact factor: 3.737
Authors: Ingo Hermann; Alena K Golla; Eloy Martínez-Heras; Ralf Schmidt; Elisabeth Solana; Sara Llufriu; Achim Gass; Lothar R Schad; Frank G Zöllner Journal: BMC Med Imaging Date: 2021-07-08 Impact factor: 1.930