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Literature DB >> 3189040

A novel method for the sampling of synovial fluid in mice. Assay of a synovial lysosomal enzyme in zymosan-induced arthritis.

Abstract

A novel and very useful technique was developed to assay a lysosomal enzyme released into the joint synovial fluid during zymosan-induced arthritis in mice. This beta-glucuronidase activity correlated with histomorphological changes observed in the joint: vasculitis, synovitis and pannus formation. The antiarthritic drug triamcinolone acetonide improved both biochemical and histological parameters.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1988 PMID： 3189040 DOI： 10.1007/bf01969105

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

15 in total

1. Effects of anti-inflammatory and other compounds on the release of lysosomal enzymes from macrophages.

Authors: P S Ringrose; M A Parr; M McLaren
Journal: Biochem Pharmacol Date: 1975-03-01 Impact factor: 5.858

2. Studies on antigen-induced arthritis in mice. II. Immunologic correlates of arthritis susceptibility in mice.

Authors: D Brackertz; G F Mitchell; M A Vadas; I R Mackay; J F Miller
Journal: J Immunol Date: 1977-05 Impact factor: 5.422

3. Complement activation by the alternative pathway and macrophage enzyme secretion in the pathogenesis of chronic inflammation.

Authors: H U Schorlemmer; D Bitter-Suermann; A C Allison
Journal: Immunology Date: 1977-06 Impact factor: 7.397

Review 4. Etiopathogenesis of murine SLE.

Authors: A N Theofilopoulos; F J Dixon
Journal: Immunol Rev Date: 1981 Impact factor: 12.988

5. Zymosan-induced arthritis: a model of chronic proliferative arthritis following activation of the alternative pathway of complement.

Authors: E C Keystone; H U Schorlemmer; C Pope; A C Allison
Journal: Arthritis Rheum Date: 1977 Sep-Oct

6. Detection and quantification of experimental joint inflammation in mice by measurement of 99mTc-pertechnetate uptake.

Authors: M W Kruijsen; W B van den Berg; L B van de Putte; W J van den Broek
Journal: Agents Actions Date: 1981-12

7. Etiopathogenesis of the rheumatoid arthritis-like disease in MRL/l mice. I. The histomorphologic basis of joint destruction.

Authors: F X O'Sullivan; H G Fassbender; S Gay; W J Koopman
Journal: Arthritis Rheum Date: 1985-05

8. Chronic immune synovitis in rabbits. I. Immunoglobulin and beta-glucuronidase analyses of synovial tissues and joint exudates.

Authors: M B Goldlust; L C Rich
Journal: Agents Actions Date: 1981-12

A novel method for the sampling of synovial fluid in mice. Assay of a synovial lysosomal enzyme in zymosan-induced arthritis.

1. Effects of anti-inflammatory and other compounds on the release of lysosomal enzymes from macrophages.

2. Studies on antigen-induced arthritis in mice. II. Immunologic correlates of arthritis susceptibility in mice.

3. Complement activation by the alternative pathway and macrophage enzyme secretion in the pathogenesis of chronic inflammation.

Review 4. Etiopathogenesis of murine SLE.

5. Zymosan-induced arthritis: a model of chronic proliferative arthritis following activation of the alternative pathway of complement.

6. Detection and quantification of experimental joint inflammation in mice by measurement of 99mTc-pertechnetate uptake.

7. Etiopathogenesis of the rheumatoid arthritis-like disease in MRL/l mice. I. The histomorphologic basis of joint destruction.

8. Chronic immune synovitis in rabbits. I. Immunoglobulin and beta-glucuronidase analyses of synovial tissues and joint exudates.

9. Monoclonal IgM rheumatoid factors derived from arthritic MRL/Mp-lpr/lpr mice.

10. A spontaneous rheumatoid arthritis-like disease in MRL/l mice.

1. RP 54745, a potential antirheumatic compound. II. In vivo properties in different animal models.

2. Inhibitory effects of Spirulina in zymosan-induced arthritis in mice.