Literature DB >> 7077223

A spontaneous rheumatoid arthritis-like disease in MRL/l mice.

L Hang, A N Theofilopoulos, F J Dixon.   

Abstract

MRL/l mice spontaneously develop an arthritis very similar in many respects to human rheumatoid arthritis. A detailed morphologic and serologic analysis of this disease revealed the following: (a) a 75% incidence of synovial and periarticular inflammation, very similar to human rheumatoid arthritis, in 5-6 mo-old females, (b) close associations between presence of joint inflammation and subsynovial and/or periarticular vasculitis, and (c) a close correlation between presence of circulating IgM rheumatoid factor (RF) and demonstrable synovial and/or joint pathology, i.e., 95% of mice with significant levels of IgMRF had synovitis and/or arthritis.

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Year:  1982        PMID： 7077223      PMCID： PMC2186697          DOI： 10.1084/jem.155.6.1690

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  29 in total

1.  Immunologic characterization of the mononuclear cell infiltrates in rheumatoid synovia, in rheumatoid nodules, and in lip biopsies from patients with Sjögren's syndrome.

Authors:  H Tannenbaum; G S Pinkus; L G Anderson; P H Schur
Journal:  Arthritis Rheum       Date:  1975 Jul-Aug

2.  Predominantly T-cell infiltrate in rheumatoid synovial membranes.

Authors:  J A Van Boxel; S A Paget
Journal:  N Engl J Med       Date:  1975-09-11       Impact factor: 91.245

Review 3.  The immunopathology of joint inflammation in rheumatoid arthritis.

Authors:  N J Zvaifler
Journal:  Adv Immunol       Date:  1973       Impact factor: 3.543

4.  Histocompatibility antigens and rheumatoid arthritis.

Authors:  R B Lies; R P Messner; G M Troup
Journal:  Arthritis Rheum       Date:  1972 Sep-Oct

5.  IgM rheumatoid factor and low molecular weight IgM. An association with vasculitis.

Authors:  A N Theofilopoulos; G Burtonboy; J J LoSpalluto; M Ziff
Journal:  Arthritis Rheum       Date:  1974 May-Jun

6.  Slowly sedimenting serum components reacting with anti-IgM sera.

Authors:  F Klein; P Mattern; H Radema; T L Van Zwet
Journal:  Immunology       Date:  1967-12       Impact factor: 7.397

7.  In vivo synthesis of IgG by rheumatoid synovium.

Authors:  A J Sliwinski; N J Zvaifler
Journal:  J Lab Clin Med       Date:  1970-08

8.  T and B lymphocytes in peripheral blood and tissue lesions in Sjögren's syndrome.

Authors:  N Talal; R A Sylvester; T E Daniels; J S Greenspan; R C Williams
Journal:  J Clin Invest       Date:  1974-01       Impact factor: 14.808

9.  In vitro synthesis of immunoglobulin by rheumatoid synovial membrane.

Authors:  J D Smiley; C Sachs; M Ziff
Journal:  J Clin Invest       Date:  1968-03       Impact factor: 14.808

10.  The pathogenesis of chronic inflammation in experimental antigen-induced arthritis. II. Preferential localization of antigen-antibody complexes to collagenous tissues.

Authors:  T D Cooke; E R Hurd; M Ziff; H E Jasin
Journal:  J Exp Med       Date:  1972-02-01       Impact factor: 14.307
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  82 in total

1.  Expression of Bcl-2 in inflammatory sites from patients with active Behçet's disease.

Authors:  K Hamzaoui; A Hamzaoui; L Zakraoui; A Chabbou
Journal:  Mediators Inflamm       Date:  1999       Impact factor: 4.711

2.  An autoimmune response to odorant binding protein 1a is associated with dry eye in the Aire-deficient mouse.

Authors:  Jason J DeVoss; Norbert P LeClair; Yafei Hou; Navdeep K Grewal; Kellsey P Johannes; Wen Lu; Ting Yang; Craig Meagher; Lawrence Fong; Erich C Strauss; Mark S Anderson
Journal:  J Immunol       Date:  2010-03-17       Impact factor: 5.422

Review 3.  Animal models of Sjögren's syndrome.

Authors:  Malin V Jonsson; Nicolas Delaleu; Roland Jonsson
Journal:  Clin Rev Allergy Immunol       Date:  2007-06       Impact factor: 8.667

4.  Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis.

Authors:  Kristine A Kuhn; Liudmila Kulik; Beren Tomooka; Kristin J Braschler; William P Arend; William H Robinson; V Michael Holers
Journal:  J Clin Invest       Date:  2006-04       Impact factor: 14.808

5.  Detection of IgG rheumatoid factor secreting cells in autoimmune MRL/1 mice: a kinetic study.

Authors:  A Tarkowski; C Czerkinsky; L A Nilsson
Journal:  Clin Exp Immunol       Date:  1984-10       Impact factor: 4.330

6.  Different effect of cyclosporin A on arthritides induced by a muramyl dipeptide analogue or the complete adjuvant in rats.

Authors:  T Sugawara; S Takada; K Furuhama; S Takayama; M Nomura; M Kato
Journal:  Int J Exp Pathol       Date:  1995-06       Impact factor: 1.925

7.  Multiple autoantigen binding capabilities of mouse monoclonal antibodies selected for rheumatoid factor activity.

Authors:  R L Rubin; R S Balderas; E M Tan; F J Dixon; A N Theofilopoulos
Journal:  J Exp Med       Date:  1984-05-01       Impact factor: 14.307

8.  Polyarthritis in MRL lpr/lpr mice.

Authors:  A Pataki; C Rordorf-Adam
Journal:  Rheumatol Int       Date:  1985       Impact factor: 2.631

9.  Analysis of circulating immune complexes from patients with ankylosing spondylitis by gel electrophoresis and immunoblotting using antiserum against a psoriasis associated retrovirus-like particle.

Authors:  E Rødahl; O J Iversen
Journal:  Ann Rheum Dis       Date:  1986-11       Impact factor: 19.103

10.  Lack of connectivity between the induced and autoimmune repertoires of lpr/lpr mice.

Authors:  D L Very; D J Panka; D Weissman; L Wysocki; T Manser; A Marshak-Rothstein
Journal:  Immunology       Date:  1993-12       Impact factor: 7.397
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