Literature DB >> 31888919

Unexpected rupture of an expectantly managed tubal ectopic pregnancy: a reminder for enhanced diligence.

Amenda Ann Davis1, Kusum Lata2, Akshita Panwar2, Alka Kriplani2.   

Abstract

Expectant management of tubal ectopic pregnancies is a feasible and possibly preferable method of management in asymptomatic women with low serum β-human chorionic gonadotropin (hCG). This involves serial monitoring of β-hCG until negative, after which it is deemed as spontaneously resolved ectopic pregnancy. We describe a case of tubal ectopic pregnancy which was expectantly managed with an initial β-hCG of 585 mIU/mL until undetectable. This patient presented with ruptured ectopic pregnancy 8 weeks after the original diagnosis, at the level of 5 mIU/mL. This highlights the importance of close monitoring in the expectant management of tubal ectopic pregnancies, with the incorporation of imaging, even when serial β-hCG shows a persistently reducing trend. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  obstetrics and gynaecology; pregnancy

Mesh:

Substances:

Year:  2019        PMID: 31888919      PMCID: PMC6936481          DOI: 10.1136/bcr-2019-230876

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

1.  Tubal rupture despite low and declining serum hCG levels.

Authors:  S Kooi; H C Kock; F H van Etten
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  1992-08-21       Impact factor: 2.435

2.  Diagnosis and Management of Ectopic Pregnancy: Green-top Guideline No. 21.

Authors: 
Journal:  BJOG       Date:  2016-11-03       Impact factor: 6.531

3.  Expectant treatment of ectopic pregnancies: clinical and sonographic predictors.

Authors:  M Atri; C M Chow; G Kintzen; P Gillett; A A Aldis; M Thibodeau; C Reinhold; P M Bret
Journal:  AJR Am J Roentgenol       Date:  2001-01       Impact factor: 3.959

4.  Rupture of ectopic pregnancy in women with low and declining serum beta-human chorionic gonadotropin concentrations.

Authors:  T Tulandi; R Hemmings; F Khalifa
Journal:  Fertil Steril       Date:  1991-10       Impact factor: 7.329

5.  Spontaneous resolution of ectopic tubal pregnancy: natural history.

Authors:  E Shalev; D Peleg; A Tsabari; S Romano; M Bustan
Journal:  Fertil Steril       Date:  1995-01       Impact factor: 7.329

6.  Expectant management of tubal ectopic pregnancy: prediction of successful outcome using decision tree analysis.

Authors:  J Elson; A Tailor; S Banerjee; R Salim; K Hillaby; D Jurkovic
Journal:  Ultrasound Obstet Gynecol       Date:  2004-06       Impact factor: 7.299

7.  Methotrexate or expectant management in women with an ectopic pregnancy or pregnancy of unknown location and low serum hCG concentrations? A randomized comparison.

Authors:  N M van Mello; F Mol; H R Verhoeve; M van Wely; A H Adriaanse; E A Boss; A B Dijkman; N Bayram; M H Emanuel; J Friederich; L van der Leeuw-Harmsen; J P Lips; M A Van Kessel; W M Ankum; F van der Veen; B W Mol; P J Hajenius
Journal:  Hum Reprod       Date:  2012-10-18       Impact factor: 6.918

8.  Single-dose systemic methotrexate vs expectant management for treatment of tubal ectopic pregnancy: a placebo-controlled randomized trial.

Authors:  D Jurkovic; M Memtsa; E Sawyer; A N A Donaldson; A Jamil; K Schramm; Y Sana; M Otify; L Farahani; N Nunes; G Ambler; J A Ross
Journal:  Ultrasound Obstet Gynecol       Date:  2017-01-06       Impact factor: 7.299

9.  Ectopic pregnancy: when is expectant management safe?

Authors:  Sharon P Rodrigues; Kirsten J de Burlet; Ellen Hiemstra; Andries R H Twijnstra; Erik W van Zwet; Trudy C M Trimbos-Kemper; Frank W Jansen
Journal:  Gynecol Surg       Date:  2012-03-06

10.  Serum Human Chorionic Gonadotropin (β- hCG) Clearance Curves in Women with Successfully Expectantly Managed Tubal Ectopic Pregnancies: A Retrospective Cohort Study.

Authors:  Samir Helmy; Dimitrios Mavrelos; Elinor Sawyer; Jara Ben-Nagi; Marianne Koch; Andrea Day; Davor Jurkovic
Journal:  PLoS One       Date:  2015-07-02       Impact factor: 3.240

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