| Literature DB >> 31888835 |
Mahdi Rahimi1, Ehsan Bahojb Noruzi2, Elham Sheykhsaran3, Baharin Ebadi2, Zahra Kariminezhad4, Morteza Molaparast5, Mojtaba Ghanbari Mehrabani4, Bahareh Mehramouz6, Mehdi Yousefi7, Raman Ahmadi4, Bahman Yousefi6, Khudaverdi Ganbarov8, Fadhil S Kamounah9, Vahid Shafiei-Irannejad10, Hossein Samadi Kafil11.
Abstract
Wound healing is a dynamic and complex process which affects the quality of life in patients and annually causes high costs for the health system, worldwide. Polymers from natural origins such as polysaccharides have gained particular interest between researchers for wound dressing applications due to their abundance in nature, biocompatibility with human tissues, and ideal physicochemical properties. Aside from their supportive effect in wound care, polysaccharides and their derivatives can actively contribute to the healing process. Silver nanoparticles are widely used noble metal nanoparticles incorporated in wound dressings due to their low toxicity for human cells, naturally availability, and strong antimicrobial effects. In the present study, we will review the most frequently used polysaccharides in wound dressing procedure with silver or silver nanoparticles accommodated. The methods of synthesis, physicochemical properties, healing efficiencies, toxicity against human tissues, antibacterial and antifungal effects of each material will also be discussed.Entities:
Keywords: Anti-microbial; Biomedical applications; Carbohydrate polymer; Nanocomposite; Polysaccharides; Silver nanoparticles; Wound dressing
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Year: 2019 PMID： 31888835 DOI： 10.1016/j.carbpol.2019.115696
Source DB: PubMed Journal: Carbohydr Polym ISSN： 0144-8617 Impact factor: 9.381