Khaled Abid Althaqafi1, Julian Satterthwaite2, Nikolaos Silikas3. 1. Faculty of Dentistry, Collage of Dental Medicine, University of Umm Al Qura, Makkah, Saudi Arabia; Division of Dentistry, School of Medical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PL, United Kingdom. 2. Division of Dentistry, School of Medical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PL, United Kingdom. 3. Division of Dentistry, School of Medical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PL, United Kingdom. Electronic address: Nikolaos.Silikas@manchester.ac.uk.
Abstract
OBJECTIVE: This study systematically reviews the literature on self-healing microcapsule technology and evaluates the biocompatibility of self-healing microcapsules and the efficiency of crack repair within resin-based dental composites. METHODS: An electronic search was carried out using the following databases: MedLine (PubMed), Embase, the Cochrane Library and Google Scholar. All titles and abstracts of the articles and patents found were analysed and selected according to the eligibility criteria. Only studies published in English were included; the outcomes sought for this review were dental resin composites with self-healing potential. There were no restrictions on the type of self-healing system involved in dental resin composites. RESULTS: The search yielded 10 studies and 2 patents involving self-healing approaches to dental resin composites. According to the current literature on self-healing dental resin composites, when a crack or damage occurs to the composite, microcapsules rupture, releasing the healing agent to repair the crack with a self-healing performance ranging from 25% to 80% of the virgin fracture toughness. SIGNIFICANCE: Self-healing strategies used with resin composite materials have, to date, been bioinspired. So far, self-healing microcapsule systems within dental composites include poly urea-formaldehyde (PUF) or silica microcapsules. The main healing agents used in PUF microcapsules are DCPD monomer and TEGDMA-DHEPT, with other agents also explored. Silica microcapsules use water/polyacid as a healing agent. All self-healing systems have shown promising results for self-repair and crack inhibition, suggesting a prolonged life of dental composite restorations. More investigations and mechanical enhancements should be directed toward self-healing technologies in dental resin composites.
OBJECTIVE: This study systematically reviews the literature on self-healing microcapsule technology and evaluates the biocompatibility of self-healing microcapsules and the efficiency of crack repair within resin-based dental composites. METHODS: An electronic search was carried out using the following databases: MedLine (PubMed), Embase, the Cochrane Library and Google Scholar. All titles and abstracts of the articles and patents found were analysed and selected according to the eligibility criteria. Only studies published in English were included; the outcomes sought for this review were dental resin composites with self-healing potential. There were no restrictions on the type of self-healing system involved in dental resin composites. RESULTS: The search yielded 10 studies and 2 patents involving self-healing approaches to dental resin composites. According to the current literature on self-healing dental resin composites, when a crack or damage occurs to the composite, microcapsules rupture, releasing the healing agent to repair the crack with a self-healing performance ranging from 25% to 80% of the virgin fracture toughness. SIGNIFICANCE: Self-healing strategies used with resin composite materials have, to date, been bioinspired. So far, self-healing microcapsule systems within dental composites include poly urea-formaldehyde (PUF) or silica microcapsules. The main healing agents used in PUF microcapsules are DCPD monomer and TEGDMA-DHEPT, with other agents also explored. Silica microcapsules use water/polyacid as a healing agent. All self-healing systems have shown promising results for self-repair and crack inhibition, suggesting a prolonged life of dental composite restorations. More investigations and mechanical enhancements should be directed toward self-healing technologies in dental resin composites.