Literature DB >> 31878521

Visible-light silicon nitride waveguide devices and implantable neurophotonic probes on thinned 200 mm silicon wafers.

Wesley D Sacher, Xianshu Luo, Yisu Yang, Fu-Der Chen, Thomas Lordello, Jason C C Mak, Xinyu Liu, Ting Hu, Tianyuan Xue, Patrick Guo-Qiang Lo, Michael L Roukes, Joyce K S Poon.   

Abstract

We present passive, visible light silicon nitride waveguides fabricated on ≈ 100 µm thick 200 mm silicon wafers using deep ultraviolet lithography. The best-case propagation losses of single-mode waveguides were ≤ 2.8 dB/cm and ≤ 1.9 dB/cm over continuous wavelength ranges of 466-550 nm and 552-648 nm, respectively. In-plane waveguide crossings and multimode interference power splitters are also demonstrated. Using this platform, we realize a proof-of-concept implantable neurophotonic probe for optogenetic stimulation of rodent brains. The probe has grating coupler emitters defined on a 4 mm long, 92 µm thick shank and operates over a wide wavelength range of 430-645 nm covering the excitation spectra of multiple opsins and fluorophores used for brain stimulation and imaging.

Entities:  

Year:  2019        PMID: 31878521      PMCID: PMC7046040          DOI: 10.1364/OE.27.037400

Source DB:  PubMed          Journal:  Opt Express        ISSN: 1094-4087            Impact factor:   3.894


  13 in total

1.  Silicon nitride CMOS-compatible platform for integrated photonics applications at visible wavelengths.

Authors:  Sebastian Romero-García; Florian Merget; Frank Zhong; Hod Finkelstein; Jeremy Witzens
Journal:  Opt Express       Date:  2013-06-17       Impact factor: 3.894

Review 2.  In vivo application of optogenetics for neural circuit analysis.

Authors:  Xue Han
Journal:  ACS Chem Neurosci       Date:  2012-07-16       Impact factor: 4.418

3.  Large-scale nanophotonic phased array.

Authors:  Jie Sun; Erman Timurdogan; Ami Yaacobi; Ehsan Shah Hosseini; Michael R Watts
Journal:  Nature       Date:  2013-01-10       Impact factor: 49.962

4.  Proximal and distal modulation of neural activity by spatially confined optogenetic activation with an integrated high-density optoelectrode.

Authors:  Sarah Libbrecht; Luis Hoffman; Marleen Welkenhuysen; Chris Van den Haute; Veerle Baekelandt; Dries Braeken; Sebastian Haesler
Journal:  J Neurophysiol       Date:  2018-03-28       Impact factor: 2.714

Review 5.  The fluorescent protein palette: tools for cellular imaging.

Authors:  Richard N Day; Michael W Davidson
Journal:  Chem Soc Rev       Date:  2009-08-04       Impact factor: 54.564

6.  Sensitive red protein calcium indicators for imaging neural activity.

Authors:  Hod Dana; Boaz Mohar; Yi Sun; Sujatha Narayan; Andrew Gordus; Jeremy P Hasseman; Getahun Tsegaye; Graham T Holt; Amy Hu; Deepika Walpita; Ronak Patel; John J Macklin; Cornelia I Bargmann; Misha B Ahrens; Eric R Schreiter; Vivek Jayaraman; Loren L Looger; Karel Svoboda; Douglas S Kim
Journal:  Elife       Date:  2016-03-24       Impact factor: 8.140

7.  Patterned photostimulation via visible-wavelength photonic probes for deep brain optogenetics.

Authors:  Eran Segev; Jacob Reimer; Laurent C Moreaux; Trevor M Fowler; Derrick Chi; Wesley D Sacher; Maisie Lo; Karl Deisseroth; Andreas S Tolias; Andrei Faraon; Michael L Roukes
Journal:  Neurophotonics       Date:  2016-12-06       Impact factor: 3.593

Review 8.  Optogenetics: 10 years of microbial opsins in neuroscience.

Authors:  Karl Deisseroth
Journal:  Nat Neurosci       Date:  2015-09       Impact factor: 24.884

9.  Ultrasensitive fluorescent proteins for imaging neuronal activity.

Authors:  Tsai-Wen Chen; Trevor J Wardill; Yi Sun; Stefan R Pulver; Sabine L Renninger; Amy Baohan; Eric R Schreiter; Rex A Kerr; Michael B Orger; Vivek Jayaraman; Loren L Looger; Karel Svoboda; Douglas S Kim
Journal:  Nature       Date:  2013-07-18       Impact factor: 49.962

10.  Multisite silicon neural probes with integrated silicon nitride waveguides and gratings for optogenetic applications.

Authors:  Euijae Shim; Yu Chen; Sotiris Masmanidis; Mo Li
Journal:  Sci Rep       Date:  2016-03-04       Impact factor: 4.379

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  3 in total

Review 1.  Integrated Neurophotonics: Toward Dense Volumetric Interrogation of Brain Circuit Activity-at Depth and in Real Time.

Authors:  Laurent C Moreaux; Dimitri Yatsenko; Wesley D Sacher; Jaebin Choi; Changhyuk Lee; Nicole J Kubat; R James Cotton; Edward S Boyden; Michael Z Lin; Lin Tian; Andreas S Tolias; Joyce K S Poon; Kenneth L Shepard; Michael L Roukes
Journal:  Neuron       Date:  2020-10-14       Impact factor: 17.173

2.  Optimization of Silicon Nitride Waveguide Platform for On-Chip Virus Detection.

Authors:  Raghi S El Shamy; Mohamed A Swillam; Xun Li
Journal:  Sensors (Basel)       Date:  2022-02-02       Impact factor: 3.576

3.  Optical characterization of deuterated silicon-rich nitride waveguides.

Authors:  Xavier X Chia; George F R Chen; Yanmei Cao; Peng Xing; Hongwei Gao; Doris K T Ng; Dawn T H Tan
Journal:  Sci Rep       Date:  2022-07-26       Impact factor: 4.996

  3 in total

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