Literature DB >> 31877551

Phytochemicals of garlic: Promising candidates for cancer therapy.

Yan Zhang1, Xingping Liu2, Jun Ruan3, Xuan Zhuang4, Xinzong Zhang5, Zhiming Li6.   

Abstract

Of the numerous health benefits of garlic, the anticancer effect is probably the most noticeable. Observations over the past years have shown that the consumption of garlic in the diet provides strong protection against cancer risk. Previous studies involving garlic phytochemicals have usually focused on the cancer chemopreventive properties, but there is little published evidence showing its therapeutic potential in cancer treatment. In view of the multitargeted carcinoma actions and lack of severe toxicity, some components of garlic are likely to play vital roles in the selective killing of cancer cells. However, the rational design of experimental studies and clinical trials are required to verify this concept. This paper discusses the promises and pitfalls of garlic for the treatment of cancer.
Copyright © 2019 The Author(s). Published by Elsevier Masson SAS.. All rights reserved.

Entities:  

Keywords:  Carcinogenesis; Garlic; Phytochemicals; Therapeutic property

Mesh:

Substances:

Year:  2019        PMID: 31877551     DOI: 10.1016/j.biopha.2019.109730

Source DB:  PubMed          Journal:  Biomed Pharmacother        ISSN: 0753-3322            Impact factor:   6.529


  18 in total

1.  Tobacco carcinogen 4-[methyl(nitroso)amino]-1-(3-pyridinyl)-1-butanone (NNK) drives metabolic rewiring and epigenetic reprograming in A/J mice lung cancer model and prevention with diallyl sulphide (DAS).

Authors:  Rasika R Hudlikar; Davit Sargsyan; David Cheng; Hsiao-Chen Dina Kuo; Renyi Wu; Xiaoyang Su; Ah-Ng Kong
Journal:  Carcinogenesis       Date:  2022-03-24       Impact factor: 4.944

2.  From laboratory to industrial storage - Translating volatile organic compounds into markers for assessing garlic storage quality.

Authors:  Richard A Ludlow; Gareth Evans; Michael Graz; Gracia Marti; Puri Castillo Martínez; Hilary J Rogers; Carsten T Müller
Journal:  Postharvest Biol Technol       Date:  2022-09       Impact factor: 6.751

Review 3.  Therapeutic Potential of Allicin and Aged Garlic Extract in Alzheimer's Disease.

Authors:  Paola Tedeschi; Manuela Nigro; Alessia Travagli; Martina Catani; Alberto Cavazzini; Stefania Merighi; Stefania Gessi
Journal:  Int J Mol Sci       Date:  2022-06-22       Impact factor: 6.208

Review 4.  Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment.

Authors:  Yang Zhou; Xingxuan Li; Wenyu Luo; Junfeng Zhu; Jingwen Zhao; Mengyao Wang; Lixuan Sang; Bing Chang; Bingyuan Wang
Journal:  Front Pharmacol       Date:  2022-06-13       Impact factor: 5.988

5.  Monocarboxylate transporter 1 is a novel target for breast cancer stem like-cell inhibition by diallyl trisulfide.

Authors:  Su-Hyeong Kim; Shivendra V Singh
Journal:  Mol Carcinog       Date:  2022-05-05       Impact factor: 5.139

Review 6.  Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation.

Authors:  Wamidh H Talib; Izzeddin Alsalahat; Safa Daoud; Reem Fawaz Abutayeh; Asma Ismail Mahmod
Journal:  Molecules       Date:  2020-11-14       Impact factor: 4.411

Review 7.  Allicin and Digestive System Cancers: From Chemical Structure to Its Therapeutic Opportunities.

Authors:  Mahshad Sarvizadeh; Omid Hasanpour; Zari Naderi Ghale-Noie; Samaneh Mollazadeh; Mohammad Rezaei; Hossein Pourghadamyari; Mohammadjaber Masoud Khooy; Michael Aschner; Haroon Khan; Nima Rezaei; Layla Shojaie; Hamed Mirzaei
Journal:  Front Oncol       Date:  2021-04-27       Impact factor: 6.244

8.  Effect of different combined mechanical and thermal treatments on the quality characteristics of garlic paste.

Authors:  Bin Zhang; Zhenjia Zheng; Nan Liu; Pengli Liu; Zhichang Qiu; Xuguang Qiao
Journal:  J Food Sci Technol       Date:  2020-07-09       Impact factor: 2.701

Review 9.  Prevailing Knowledge on the Bioavailability and Biological Activities of Sulphur Compounds from Alliums: A Potential Drug Candidate.

Authors:  Murugan Sesha Subramanian; Giri Nandagopal Ms; Syafinaz Amin Nordin; Karuppiah Thilakavathy; Narcisse Joseph
Journal:  Molecules       Date:  2020-09-09       Impact factor: 4.411

10.  Hyaluronic Acid-Based Nanocapsules as Efficient Delivery Systems of Garlic Oil Active Components with Anticancer Activity.

Authors:  Małgorzata Janik-Hazuka; Kamil Kamiński; Marta Kaczor-Kamińska; Joanna Szafraniec-Szczęsny; Aleksandra Kmak; Hassan Kassassir; Cezary Watała; Maria Wróbel; Szczepan Zapotoczny
Journal:  Nanomaterials (Basel)       Date:  2021-05-20       Impact factor: 5.076

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