Literature DB >> 31875976

The development of a test battery to assess the hand-eye functions relevant in predicting easy and accurate tablet subdivision in older people: A pilot study.

Diana van Riet-Nales1, Linda Donkerbroek1, Agnes Nicia1, Christien Oussoren2, Anthonius de Boer1,2, Bart van den Bemt3,4.   

Abstract

AIMS: Tablets may be subdivided for dose adaptations or to ease swallowing. The handling is common in older patients but can be difficult and inaccurate. Currently, it is not known which hand-eye functions determine the ability of older people to break tablets by hand and to do so with acceptable ease and accuracy. The aim of this study was to develop a test battery to assess the hand-eye functions relevant in predicting easy and accurate tablet subdivision in older people.
METHODS: A mixed methods study was conducted including literature reviews and a pilot experiment. The reviews were conducted in Pubmed, Google Scholar, Dutch journals and professional standards. The first review tried to identify the hand-eye functions relevant to tablet subdivision and the second the associated measuring instruments, testing protocols and normative data. A test battery was empanelled. A pilot experiment was conducted in 30 adult volunteers to optimize and evaluate the test battery.
RESULTS: Five domains were considered relevant: hand size, hand strength, flexibility/manual dexterity, vision and coordination. Hand size could best be measured by finger circumference, hand strength by pinch- and grip strength, flexibility by active range of joint motion, manual dexterity (and flexibility, coordination, cognition, vision) by pegboard function, vision by near visual acuity. Older people preferred the use of tablet splitters over hand breaking.
CONCLUSION: Easy and accurate tablet subdivision is essential to the good use of medicines. We developed a test battery for older people, but probably of value to all age groups.
© 2019 The British Pharmacological Society.

Entities:  

Keywords:  clinical pharmacology; drug information; medication errors; medication safety

Mesh:

Substances:

Year:  2020        PMID: 31875976      PMCID: PMC7495273          DOI: 10.1111/bcp.14201

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  54 in total

1.  Development of an in vivo test procedure for the ease of breaking of scored tablets.

Authors:  D M Barends; D W Groot; H W Frijlink; N Rodenhuis; J C van der Steen
Journal:  Pharmeur Sci Notes       Date:  2005-08

2.  Prediction of the ease of subdivision of scored tablets from their physical parameters.

Authors:  Koos C van der Steen; Henderik W Frijlink; C Maarten A Schipper; Dirk M Barends
Journal:  AAPS PharmSciTech       Date:  2010-01-15       Impact factor: 3.246

Review 3.  Pharmacological considerations in the elderly.

Authors:  Shamsuddin Akhtar
Journal:  Curr Opin Anaesthesiol       Date:  2018-02       Impact factor: 2.706

4.  Pharmaceutical counselling about different types of tablet-splitting methods based on the results of weighing tests and mechanical development of splitting devices.

Authors:  O Somogyi; A Meskó; L Csorba; P Szabó; R Zelkó
Journal:  Eur J Pharm Sci       Date:  2017-06-10       Impact factor: 4.384

Review 5.  A narrative review of dexterity assessments.

Authors:  Katie E Yancosek; Dana Howell
Journal:  J Hand Ther       Date:  2009-02-12       Impact factor: 1.950

6.  Marked sex differences on a fine motor skill task disappear when finger size is used as covariate.

Authors:  M Peters; P Servos; R Day
Journal:  J Appl Psychol       Date:  1990-02

Review 7.  The development of a test battery to assess the hand-eye functions relevant in predicting easy and accurate tablet subdivision in older people: A pilot study.

Authors:  Diana van Riet-Nales; Linda Donkerbroek; Agnes Nicia; Christien Oussoren; Anthonius de Boer; Bart van den Bemt
Journal:  Br J Clin Pharmacol       Date:  2020-02-11       Impact factor: 4.335

8.  Could questions on activities of daily living estimate grip strength of older adults living independently in the community?

Authors:  Jessica Simard; Maude Chalifoux; Véronique Fortin; Maude Jeanson Archambault; Anne St-Cerny-Gosselin; Johanne Desrosiers
Journal:  J Aging Res       Date:  2012-03-18

Review 9.  European Society for Swallowing Disorders - European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome.

Authors:  Laura Wj Baijens; Pere Clavé; Patrick Cras; Olle Ekberg; Alexandre Forster; Gerald F Kolb; Jean-Claude Leners; Stefano Masiero; Jesús Mateos-Nozal; Omar Ortega; David G Smithard; Renée Speyer; Margaret Walshe
Journal:  Clin Interv Aging       Date:  2016-10-07       Impact factor: 4.458

10.  Relationship between Age and the Ability to Break Scored Tablets.

Authors:  Kim Notenboom; Herman Vromans; Maarten Schipper; Hubert G M Leufkens; Marcel L Bouvy
Journal:  Front Pharmacol       Date:  2016-07-26       Impact factor: 5.810

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  5 in total

1.  Developing a novel tool to assess the ability to self-administer medication in non-demented in-hospital patients: ABLYMED study protocol.

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Journal:  BMC Geriatr       Date:  2022-05-31       Impact factor: 4.070

Review 2.  Developing patient-centric medicines for older people: Reflections from the draft EMA paper on the pharmaceutical development of medicines for use in the older population.

Authors:  Diana A van Riet-Nales; Katarina Sundberg; Anthonius de Boer; Blanka Hirschlérova
Journal:  Br J Clin Pharmacol       Date:  2020-10       Impact factor: 4.335

Review 3.  The development of a test battery to assess the hand-eye functions relevant in predicting easy and accurate tablet subdivision in older people: A pilot study.

Authors:  Diana van Riet-Nales; Linda Donkerbroek; Agnes Nicia; Christien Oussoren; Anthonius de Boer; Bart van den Bemt
Journal:  Br J Clin Pharmacol       Date:  2020-02-11       Impact factor: 4.335

4.  Comparison of tablet splitting techniques for dosing accuracy of nebivolol tablets: Hand splitting versus tablet cutter and knife.

Authors:  Seval Olgac; Duygu Yilmaz Usta; Tuba Incecayir
Journal:  Saudi Pharm J       Date:  2021-11-15       Impact factor: 4.330

5.  Demographics in the 2020s-Longevity as a challenge for pharmaceutical drug development, prescribing, dispensing, patient care and quality of life.

Authors:  Sven Stegemann; Diana van Riet-Nales; Anthonius de Boer
Journal:  Br J Clin Pharmacol       Date:  2020-10       Impact factor: 4.335

  5 in total

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