| Literature DB >> 31873768 |
Tomohiko Nakamura1,2, Masashi Suzuki3, Masamichi Ueda3, Yumiko Harada3, Masaaki Hirayama4, Masahisa Katsuno5.
Abstract
Wheelchair use is an important indicator of disease progression in Parkinson's disease (PD). Here, we investigated whether orthostatic hypotension (OH) affects the time to wheelchair use. We examined 33 PD patients with OH and 95 without OH. Median time to start using a wheelchair calculated from the time of disease onset was significantly shorter in patients with OH than in those without OH (12.0 vs 19.0 years; p < 0.001). Thus, appropriate management of OH and motor function is necessary.Entities:
Keywords: Dysautonomia; Orthostatic hypotension; Parkinson’s disease; Progression; Wheelchair
Mesh:
Year: 2019 PMID: 31873768 DOI: 10.1007/s00702-019-02127-4
Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN: 0300-9564 Impact factor: 3.575