Literature DB >> 31873263

Oral antibiotic prescribing by NHS dentists in England 2010-2017.

Martin H Thornhill1, Mark J Dayer2, Michael J Durkin3, Peter B Lockhart4, Larry M Baddour5.   

Abstract

Introduction Dentists prescribe a significant proportion of all antibiotics, while antimicrobial stewardship aims to minimise antibiotic-prescribing to reduce the risk of developing antibiotic-resistance and adverse drug reactions.Aims To evaluate NHS antibiotic-prescribing practices of dentists in England between 2010-2017.Methods NHS Digital 2010-2017 data for England were analysed to quantify dental and general primary-care oral antibiotic prescribing.Results Dental prescribing accounted for 10.8% of all oral antibiotic prescribing, 18.4% of amoxicillin and 57.0% of metronidazole prescribing in primary care. Amoxicillin accounted for 64.8% of all oral antibiotic prescribing by dentists, followed by metronidazole (28.0%), erythromycin (4.4%), phenoxymethylpenicillin (0.9%), clindamycin (0.6%), co-amoxiclav (0.5%), cephalosporins (0.4%) and tetracyclines (0.3%). Prescriptions by dentists declined during the study period for all antibiotics except for co-amoxiclav. This increase is of concern given the need to restrict co-amoxiclav use to infections where there is no alternative. Dental prescribing of clindamycin, which accounted for 43.9% of primary care prescribing in 2010, accounted for only 14.6% in 2017. Overall oral antibiotic prescribing by dentists fell 24.4% as compared to 14.8% in all of primary care.Conclusions These data suggest dentists have reduced antibiotic prescribing, possibly more than in other areas of primary-care. Nonetheless, opportunities remain for further reduction.

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Year:  2019        PMID: 31873263      PMCID: PMC7970513          DOI: 10.1038/s41415-019-1002-3

Source DB:  PubMed          Journal:  Br Dent J        ISSN: 0007-0610            Impact factor:   1.626


  45 in total

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Journal:  J Antimicrob Chemother       Date:  2007-04-19       Impact factor: 5.790

Review 2.  The role of phenoxymethylpenicillin, amoxicillin, metronidazole and clindamycin in the management of acute dentoalveolar abscesses--a review.

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Journal:  Br Dent J       Date:  2009-04-11       Impact factor: 1.626

3.  The place of metronidazole in the treatment of acute oro-facial infection.

Authors:  F J Hood
Journal:  J Antimicrob Chemother       Date:  1978-09       Impact factor: 5.790

4.  Inappropriate prescribing of antibiotics in primary dental care: reasons and resolutions.

Authors:  Anwen L Cope; Ivor G Chestnutt
Journal:  Prim Dent J       Date:  2014-11

5.  Fluoroquinolone use and associated adverse drug events in England.

Authors:  Larry M Baddour; Mark J Dayer; Martin H Thornhill
Journal:  J Infect       Date:  2018-11-13       Impact factor: 6.072

6.  Incidence and nature of adverse reactions to antibiotics used as endocarditis prophylaxis.

Authors:  Martin H Thornhill; Mark J Dayer; Bernard Prendergast; Larry M Baddour; Simon Jones; Peter B Lockhart
Journal:  J Antimicrob Chemother       Date:  2015-04-29       Impact factor: 5.790

7.  Part 1. Current prescribing trends of antibiotics by dentists in Australia from 2013 to 2016.

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Journal:  Aust Dent J       Date:  2018-05-13       Impact factor: 2.291

8.  Antibiotic overusage and resistance: A cross-sectional survey among pediatric dentists.

Authors:  Sapna Konde; Lalitha S Jairam; Preetha Peethambar; Sunil Raj Noojady; Narayan Chandra Kumar
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Review 9.  The clinical significance of anaerobic bacteria in acute orofacial odontogenic infections.

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Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2004-10

10.  Antibiotic prescribing in UK general dental practice: a cross-sectional study.

Authors:  Anwen L Cope; Nick A Francis; Fiona Wood; Ivor G Chestnutt
Journal:  Community Dent Oral Epidemiol       Date:  2015-10-27       Impact factor: 3.383

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4.  A Survey of Systemic Antibiotic Prescription Patterns Amongst Iraqi Dentists.

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Review 5.  Oral Antibiotic for Empirical Management of Acute Dentoalveolar Infections-A Systematic Review.

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Journal:  Antibiotics (Basel)       Date:  2021-02-28

6.  Antibiotic prescribing practices of dentists for endodontic infections; a cross-sectional study.

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8.  Appropriateness of Antibiotic Prescription for Prophylactic Purposes among Italian Dental Practitioners: Results from a Cross-Sectional Study.

Authors:  Aida Bianco; Vincenza Cautela; Francesco Napolitano; Francesca Licata; Maria Pavia
Journal:  Antibiotics (Basel)       Date:  2021-05-08

9.  How did COVID-19 impact on dental antibiotic prescribing across England?

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10.  Antibiotic Use in Periodontal Therapy among French Dentists and Factors Which Influence Prescribing Practices.

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Journal:  Antibiotics (Basel)       Date:  2021-03-15
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