Literature DB >> 31872

The mitochondrial localization of coproporphyrinogen III oxidase.

B Grandchamp, N Phung, Y Nordmann.   

Abstract

The location of coproporphyrinogen III oxidase in mitochondria was studied in rat liver by using the digitonin method or hypo-osmotic media for fractionation. The enzyme was found in the intermembrane space with a fraction loosely bound to the inner membrane. This fraction was released by washing the inner-membrane-matrix complex with alkaline solutions or solutions of high ionic strength. The enzyme in both fractions had the same Km (0.16 micrometer) for coproporphyrinogen III. When incubation was performed in a medium that avoided destruction of enzyme membrane binding, a dramatic increase in activity was observed after sonication of whole mitochondria or of the inner-membrane-matrix complex.

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Year:  1978        PMID: 31872      PMCID: PMC1186208          DOI: 10.1042/bj1760097

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  12 in total

1.  Mitochondrial coproporphyrinogen oxidase and protoporphyrin formation.

Authors:  S SANO; S GRANICK
Journal:  J Biol Chem       Date:  1961-04       Impact factor: 5.157

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  [Separation of the mitochondrial membranes. Purification and enzymatic characterization of the outer membrane].

Authors:  M Lévy; R Toury; J André
Journal:  Biochim Biophys Acta       Date:  1967-09-09

4.  Intramitochondrial localization of 5-aminolaevulinate synthase induced in rat liver with allylisopropylacetamide.

Authors:  F M Zuyderhoudt; P Borst; F Huijing
Journal:  Biochim Biophys Acta       Date:  1969-04-22

5.  Carnitine palmityltransferase. Location of two enzymatic activities in rat liver mitochondria.

Authors:  C L Hoppel; R J Tomec
Journal:  J Biol Chem       Date:  1972-02-10       Impact factor: 5.157

6.  Decreased lymphocyte coproporphyrinogen III oxidase activity in hereditary coproporphyria.

Authors:  B Grandchamp; Y Nordmann
Journal:  Biochem Biophys Res Commun       Date:  1977-02-07       Impact factor: 3.575

7.  The enzymic conversion of protoporphyrinogen IX to protoporphyrin IX. Protoporphyrinogen oxidase activity in mitochondrial extracts of Saccharomyces cerevisiae.

Authors:  R Poulson; W J Polglase
Journal:  J Biol Chem       Date:  1975-02-25       Impact factor: 5.157

8.  Human plasma monoamine oxidase. 1. Purification and identification.

Authors:  C M McEwen
Journal:  J Biol Chem       Date:  1965-05       Impact factor: 5.157

9.  The structural organization of haem synthesis in rat liver mitochondria.

Authors:  M S Jones; O T Jones
Journal:  Biochem J       Date:  1969-07       Impact factor: 3.857

10.  Enzymatic properties of the inner and outer membranes of rat liver mitochondria.

Authors:  C Schnaitman; J W Greenawalt
Journal:  J Cell Biol       Date:  1968-07       Impact factor: 8.077

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  22 in total

Review 1.  Iron and porphyrin trafficking in heme biogenesis.

Authors:  Iman J Schultz; Caiyong Chen; Barry H Paw; Iqbal Hamza
Journal:  J Biol Chem       Date:  2010-06-03       Impact factor: 5.157

2.  Structural basis of hereditary coproporphyria.

Authors:  Dong-Sun Lee; Eva Flachsová; Michaela Bodnárová; Borries Demeler; Pavel Martásek; C S Raman
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-21       Impact factor: 11.205

3.  Studies on the mode of action of acifluorfen-methyl in nonchlorophyllous soybean cells : accumulation of tetrapyrroles.

Authors:  M Matringe; R Scalla
Journal:  Plant Physiol       Date:  1988-02       Impact factor: 8.340

Review 4.  Molecular abnormalities of coproporphyrinogen oxidase in patients with hereditary coproporphyria.

Authors:  B Grandchamp; J Lamoril; H Puy
Journal:  J Bioenerg Biomembr       Date:  1995-04       Impact factor: 2.945

Review 5.  The mitochondrial heme metabolon: Insights into the complex(ity) of heme synthesis and distribution.

Authors:  Robert B Piel; Harry A Dailey; Amy E Medlock
Journal:  Mol Genet Metab       Date:  2019-01-17       Impact factor: 4.797

Review 6.  Trafficking of heme and porphyrins in metazoa.

Authors:  Scott Severance; Iqbal Hamza
Journal:  Chem Rev       Date:  2009-10       Impact factor: 60.622

7.  Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging.

Authors:  Hyun-Woo Rhee; Peng Zou; Namrata D Udeshi; Jeffrey D Martell; Vamsi K Mootha; Steven A Carr; Alice Y Ting
Journal:  Science       Date:  2013-01-31       Impact factor: 47.728

8.  Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase.

Authors:  P Martasek; J M Camadro; M H Delfau-Larue; J B Dumas; J J Montagne; H de Verneuil; P Labbe; B Grandchamp
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-12       Impact factor: 11.205

9.  Uptake of protoporphyrin IX by isolated rat liver mitochondria.

Authors:  M E Koller; I Romslo
Journal:  Biochem J       Date:  1980-05-15       Impact factor: 3.857

10.  Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis.

Authors:  D Urban-Grimal; R Labbe-Bois
Journal:  Mol Gen Genet       Date:  1981
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