Literature DB >> 31863119

Targeting pyrimidine metabolism for glioblastoma therapy.

Veerakumar Balasubramaniyan1, Krishna Bhat2.   

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Year:  2020        PMID： 31863119      PMCID： PMC7032621          DOI： 10.1093/neuonc/noz239

Source DB:  PubMed          Journal:  Neuro Oncol        ISSN： 1522-8517            Impact factor:   12.300


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  9 in total

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2.  Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.

Authors:  Martina Bajzikova; Jaromira Kovarova; Ana R Coelho; Stepana Boukalova; Sehyun Oh; Katerina Rohlenova; David Svec; Sona Hubackova; Berwini Endaya; Kristyna Judasova; Ayenachew Bezawork-Geleta; Katarina Kluckova; Laurent Chatre; Renata Zobalova; Anna Novakova; Katerina Vanova; Zuzana Ezrova; Ghassan J Maghzal; Silvia Magalhaes Novais; Marie Olsinova; Linda Krobova; Yong Jin An; Eliska Davidova; Zuzana Nahacka; Margarita Sobol; Teresa Cunha-Oliveira; Cristian Sandoval-Acuña; Hynek Strnad; Tongchuan Zhang; Thanh Huynh; Teresa L Serafim; Pavel Hozak; Vilma A Sardao; Werner J H Koopman; Miria Ricchetti; Paulo J Oliveira; Frantisek Kolar; Mikael Kubista; Jaroslav Truksa; Katerina Dvorakova-Hortova; Karel Pacak; Robert Gurlich; Roland Stocker; Yaoqi Zhou; Michael V Berridge; Sunghyouk Park; Lanfeng Dong; Jakub Rohlena; Jiri Neuzil
Journal:  Cell Metab       Date:  2018-11-15       Impact factor: 27.287

3.  Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

Authors:  David B Sykes; Youmna S Kfoury; François E Mercier; Mathias J Wawer; Jason M Law; Mark K Haynes; Timothy A Lewis; Amir Schajnovitz; Esha Jain; Dongjun Lee; Hanna Meyer; Kerry A Pierce; Nicola J Tolliday; Anna Waller; Steven J Ferrara; Ashley L Eheim; Detlef Stoeckigt; Katrina L Maxcy; Julien M Cobert; Jacqueline Bachand; Brian A Szekely; Siddhartha Mukherjee; Larry A Sklar; Joanne D Kotz; Clary B Clish; Ruslan I Sadreyev; Paul A Clemons; Andreas Janzer; Stuart L Schreiber; David T Scadden
Journal:  Cell       Date:  2016-09-15       Impact factor: 41.582

4.  Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells.

Authors:  Xiuxing Wang; Kailin Yang; Qiulian Wu; Leo J Y Kim; Andrew R Morton; Ryan C Gimple; Briana C Prager; Yu Shi; Wenchao Zhou; Shruti Bhargava; Zhe Zhu; Li Jiang; Weiwei Tao; Zhixin Qiu; Linjie Zhao; Guoxing Zhang; Xiqing Li; Sameer Agnihotri; Paul S Mischel; Stephen C Mack; Shideng Bao; Jeremy N Rich
Journal:  Sci Transl Med       Date:  2019-08-07       Impact factor: 17.956

5.  Teriflunomide, an inhibitor of dihydroorotate dehydrogenase for the potential oral treatment of multiple sclerosis.

Authors:  Alan M Palmer
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6.  PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition.

Authors:  Deepti Mathur; Elias Stratikopoulos; Sait Ozturk; Nicole Steinbach; Sarah Pegno; Sarah Schoenfeld; Raymund Yong; Vundavalli V Murty; John M Asara; Lewis C Cantley; Ramon Parsons
Journal:  Cancer Discov       Date:  2017-03-02       Impact factor: 39.397

7.  Discovery of a new pyrimidine synthesis inhibitor eradicating glioblastoma-initiating cells.

Authors:  Smile Echizenya; Yukiko Ishii; Satoshi Kitazawa; Tadashi Tanaka; Shun Matsuda; Eriko Watanabe; Masao Umekawa; Shunsuke Terasaka; Kiyohiro Houkin; Tomohisa Hatta; Tohru Natsume; Yoshimasa Maeda; Shin-Ichi Watanabe; Shinji Hagiwara; Toru Kondo
Journal:  Neuro Oncol       Date:  2020-02-20       Impact factor: 12.300

Review 8.  Dissecting human gliomas by single-cell RNA sequencing.

Authors:  Itay Tirosh; Mario L Suvà
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9.  DHODH modulates transcriptional elongation in the neural crest and melanoma.

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Journal:  Nature       Date:  2011-03-24       Impact factor: 49.962
  9 in total
  2 in total

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Journal:  Cell Death Dis       Date:  2022-02-15       Impact factor: 9.685

2.  A novel signature based on necroptosis-related long non-coding RNAs for predicting prognosis of patients with glioma.

Authors:  Pengfei Xia; Yimin Huang; Gang Chen
Journal:  Front Oncol       Date:  2022-08-10       Impact factor: 5.738
  2 in total

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