Literature DB >> 31862546

Head and neck free flap survival when requiring interposition vein grafting: A multi-instiutional review.

Nolan B Seim1, Matthew Old2, Daniel Petrisor3, William Thomas3, Akash Naik2, Alia J Mowery3, Stephen Kang2, Ryan Li3, Mark K Wax4.   

Abstract

OBJECTIVE: Interposition vein grafting in free flap reconstruction is often viewed as a risky procedure, but is necessary in cases of inadequate pedicle length.
MATERIALS AND METHODS: Two tertiary care centers retrospectively.reviewed 3008 head and neck free flap reconstructions from 2008 to 2017 91 patients were identified requiring interposition vein grafting during reconstruction. Pre and perioperative characteristics were recorded Univariate and multivariate analyses were conducted with a p value <0.05 indicating statistical significance.
RESULTS: Of the 91 patients 75% had undergone reconstruction for cancer, 66% of these cases were in the setting of recurrence or complication, 33% had a previous free flap, and 52% had prior radiation therapy. Surgical site was primarily craniofacial (36%) or oral cavity (26%). The majority of vein grafts were saphenous (64%), average graft length 18 cm (SD 11 cm). Half were used for both artery and vein anastomosis. Flap survival was 85% overall and only prior free flap was predictive of failure on multivariate analysis. No other peri-operative or graft variable assessed in this study were predictive of flap failure.
CONCLUSION: In a multi-institutional study of head and neck free flap reconstructions using interposition vein grafts, we identified an overall 85% success rate with no significant difference between soft tissue and osteocutaneous flaps despite the complicated nature of these cases.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Free flap; Head and neck reconstruction; Interposition; Survival; Vein graft

Mesh:

Year:  2019        PMID: 31862546     DOI: 10.1016/j.oraloncology.2019.104482

Source DB:  PubMed          Journal:  Oral Oncol        ISSN: 1368-8375            Impact factor:   5.337


  4 in total

Review 1.  Vein Grafts in Free Flap Reconstruction: Review of Indications and Institutional Pearls.

Authors:  Hannah C Langdell; Ronnie L Shammas; Andrew Atia; Edward I Chang; Evan Matros; Brett T Phillips
Journal:  Plast Reconstr Surg       Date:  2022-03-01       Impact factor: 4.730

2.  Optimization of Vascular Supply in Free Flaps for Head and Neck Reconstruction: Analysis of a Young Team's Experience.

Authors:  Paolo Iacoviello; Susanna Bacigaluppi; Simone Callegari; Carlo Rossello; Andrea Antonini; Marco Gramegna; Mariano Da Rold; Giuseppe Signorini; Giuseppe Verrina
Journal:  Front Surg       Date:  2022-06-30

3.  Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization.

Authors:  Yao Liu; Xueying Zhuang; Si Yu; Ning Yang; Jianhong Zeng; Xuemei Liu; Xu Chen
Journal:  Stem Cell Res Ther       Date:  2021-01-22       Impact factor: 6.832

4.  Effects of endothelial defects and venous interposition grafts on the acute incidence of thrombus formation within microvascular procedures.

Authors:  Andreas M Fichter; Thomas Mücke; Lucas M Ritschl; Marie-Kristin Hofmann; Constantin T Wolff; Leonard H Schmidt; Klaus-Dietrich Wolff
Journal:  Sci Rep       Date:  2021-04-22       Impact factor: 4.379

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.