Literature DB >> 31847616

Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics.

Alan Talevi1,2, Carolina L Bellera1,2.   

Abstract

Keywords:  Drug repurposing; big data; crowdsourcing; drug repositioning; economics; intellectual property; neglected diseases; precision medicine; rare diseases

Mesh：

Year:  2019        PMID： 31847616     DOI： 10.1080/17460441.2020.1704729

Source DB:  PubMed          Journal:  Expert Opin Drug Discov        ISSN： 1746-0441            Impact factor:   6.098


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  44 in total

Review 1.  Screening Repurposing Libraries for Identification of Drugs with Novel Antifungal Activity.

Authors:  Gina Wall; Jose L Lopez-Ribot
Journal:  Antimicrob Agents Chemother       Date:  2020-08-20       Impact factor: 5.191

Review 2.  Significant perspectives on various viral infections targeted antiviral drugs and vaccines including COVID-19 pandemicity.

Authors:  Gandarvakottai Senthilkumar Arumugam; Kannan Damodharan; Mukesh Doble; Sathiah Thennarasu
Journal:  Mol Biomed       Date:  2022-07-15

3.  Exploring Amodiaquine's Repurposing Potential in Breast Cancer Treatment-Assessment of In-Vitro Efficacy & Mechanism of Action.

Authors:  Vineela Parvathaneni; Rameswari Chilamakuri; Nishant S Kulkarni; Nabeela F Baig; Saurabh Agarwal; Vivek Gupta
Journal:  Int J Mol Sci       Date:  2022-09-28       Impact factor: 6.208

Review 4.  Drug repurposing-an emerging strategy in cancer therapeutics.

Authors:  Khadija Shahab Turabi; Ankita Deshmukh; Sayan Paul; Dayanand Swami; Shafina Siddiqui; Urwashi Kumar; Shreelekha Naikar; Shine Devarajan; Soumya Basu; Manash K Paul; Jyotirmoi Aich
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2022-06-13       Impact factor: 3.195

5.  D,L-Lysine-Acetylsalicylate + Glycine (LASAG) Reduces SARS-CoV-2 Replication and Shows an Additive Effect with Remdesivir.

Authors:  Johannes Jungwirth; Clio Häring; Sarah König; Liane Giebeler; Heena Doshi; Christian Brandt; Stefanie Deinhardt-Emmer; Bettina Löffler; Christina Ehrhardt
Journal:  Int J Mol Sci       Date:  2022-06-21       Impact factor: 6.208

Review 6.  Teaching an old dog new tricks: Drug discovery by repositioning natural products and their derivatives.

Authors:  Boshi Huang; Yan Zhang
Journal:  Drug Discov Today       Date:  2022-02-16       Impact factor: 8.369

Review 7.  Repurposing of antibiotics for clinical management of COVID-19: a narrative review.

Authors:  Abdourahamane Yacouba; Ahmed Olowo-Okere; Ismaeel Yunusa
Journal:  Ann Clin Microbiol Antimicrob       Date:  2021-05-21       Impact factor: 3.944

8.  Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice.

Authors:  Young Joo Sun; Gabriel Velez; Dylan E Parsons; Kun Li; Miguel E Ortiz; Shaunik Sharma; Paul B McCray; Alexander G Bassuk; Vinit B Mahajan
Journal:  J Clin Invest       Date:  2021-05-17       Impact factor: 19.456

9.  In Esophageal Squamous Cells From Eosinophilic Esophagitis Patients, Th2 Cytokines Increase Eotaxin-3 Secretion Through Effects on Intracellular Calcium and a Non-Gastric Proton Pump.

Authors:  Eunice Odiase; Xi Zhang; Yan Chang; Melissa Nelson; Uthra Balaji; Jinghua Gu; Qiuyang Zhang; Zui Pan; Stuart Jon Spechler; Rhonda F Souza
Journal:  Gastroenterology       Date:  2021-02-11       Impact factor: 33.883

10.  Computational Insights on the Potential of Some NSAIDs for Treating COVID-19: Priority Set and Lead Optimization.

Authors:  Ayman Abo Elmaaty; Mohammed I A Hamed; Muhammad I Ismail; Eslam B Elkaeed; Hamada S Abulkhair; Muhammad Khattab; Ahmed A Al-Karmalawy
Journal:  Molecules       Date:  2021-06-21       Impact factor: 4.411
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