Highly Permeable Monolith-based Multichannel In-Tip Microextraction Apparatus for Simultaneous Field Sample Preparation of Pesticides and Heavy Metal Ions in Environmental Waters.

A portable multichannel in-tip microextraction-based field sample preparation (FSP) apparatus was developed using polymer-based monoliths as an extraction phase. The construction of the FSP device is quite facile and convenient. More specifically, according to the chemical properties of studied analytes, functional-rich and high-permeability monoliths were in situ synthesized in pipet tips. After that, three tips containing the sorbents were mounted to three syringes, which were connected to a screw motor employed to drive the syringes and accurately regulate the flow rates in the adsorption and desorption stages. Because of the multifunction groups in the monoliths, the sorbents displayed satisfactory coextraction performance for pesticides (carbamates and triazoles) and heavy metal ions (Cd2+, Pb2+, and Cu2+) under the optimized conditions. The practicability of the proposed apparatus was demonstrated by the quick and simultaneous FSP of studied analytes in various environmental waters and combined with high-performance liquid chromatography/diode-array detection (for pesticides) and atomic absorption spectrometry (for metal ion) analysis. The results indicated that the limits of detection for the pesticides and metal ions were in the range of 0.36 to 1.2 ng/L and 0.061 to 0.40 ng/L, respectively, with ideal coefficients of determination. Furthermore, the results obtained with the constructed device were quite comparable to those obtained with the traditional laboratory extraction process, which demonstrated that the newly developed apparatus possesses the expected application in the high-throughput FSP of pesticides and heavy metal ions in water samples.