Literature DB >> 3182557

Production of IGF-II-related peptide by an anaplastic cell line (AT-3) established from the Dunning prostatic carcinoma of rats.

Y Matuo1, N Nishi, H Tanaka, I Sasaki, J T Isaacs, F Wada.   

Abstract

AT-3 cells, one of anaplastic cell lines established from the Dunning prostatic carcinoma of rats, were able to grow under serum-free conditions in a state of suspension detached from a substratum. Radioimmunoassay using monoclonal antibody against rat insulin-like growth factor II (IGF-II) revealed the presence of IGF-II-related peptide in acid-ethanol extracts of lyophilized serum-free media conditioned by AT-3 cells. The peptide contents in the culture media increased with increase in cell number; 71 ng at 3.0 X 10(6) cells and 449 ng at 4.6 X 10(7) cells. IGF-II-related peptide was hardly detectable in acid-ethanol extracts of AT-3 cells harvested after 13-days culture. These results indicate that AT-3 cells produce IGF-II-related peptide and may release it into the culture media.

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Year:  1988        PMID： 3182557     DOI： 10.1007/bf02620881

Source DB:  PubMed          Journal:  In Vitro Cell Dev Biol        ISSN： 0883-8364


  22 in total

1.  Insulin-like growth factor gene expression during rat embryonic development.

Authors:  P Rotwein; K M Pollock; M Watson; J D Milbrandt
Journal:  Endocrinology       Date:  1987-12       Impact factor: 4.736

2.  Radioligand assays for insulin-like growth factor II.

Authors:  W H Daughaday
Journal:  Methods Enzymol       Date:  1987       Impact factor: 1.600

3.  Liver plasma membranes and proteoglycan prepared therefrom inhibit the growth of hepatoma cells in vitro.

Authors:  H Kawakami; H Terayama
Journal:  Biochim Biophys Acta       Date:  1981-08-06

4.  Stabilization of fibroblast growth factors by a non-cytotoxic zwitterionic detergent, 3-[(3-cholamidopropyl)dimethylammonio]-1-propane sulfonate (CHAPS).

Authors:  Y Matuo; N Nishi; Y Muguruma; Y Yoshitake; Y Masuda; K Nishikawa; F Wada
Journal:  In Vitro Cell Dev Biol       Date:  1988-05

5.  Inhibition of vascular smooth muscle cell growth by endothelial cell-derived heparin. Possible role of a platelet endoglycosidase.

Authors:  J J Castellot; L V Favreau; M J Karnovsky; R D Rosenberg
Journal:  J Biol Chem       Date:  1982-10-10       Impact factor: 5.157

6.  Culturing chick muscle cells on glycosaminoglycan substrates: attachment and differentiation.

Authors:  M J Kujawa; K Tepperman
Journal:  Dev Biol       Date:  1983-10       Impact factor: 3.582

7.  Cell specific effects of glycosaminoglycans on the attachment and proliferation of vascular wall components.

Authors:  A Orlidge; P A D'Amore
Journal:  Microvasc Res       Date:  1986-01       Impact factor: 3.514

8.  Expression of insulin-like growth factor-II transcripts in Wilms' tumour.

Authors:  A E Reeve; M R Eccles; R J Wilkins; G I Bell; L J Millow
Journal:  Nature       Date:  1985 Sep 19-25       Impact factor: 49.962

9.  Inhibition of leukocyte locomotion by hyaluronic acid.

Authors:  J V Forrester; P C Wilkinson
Journal:  J Cell Sci       Date:  1981-04       Impact factor: 5.285

10.  Cultured endothelial cells produce a heparinlike inhibitor of smooth muscle cell growth.

Authors:  J J Castellot; M L Addonizio; R Rosenberg; M J Karnovsky
Journal:  J Cell Biol       Date:  1981-08       Impact factor: 10.539
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  2 in total

Review 1.  The insulin-like growth factor system in the prostate.

Authors:  D M Peehl; P Cohen; R G Rosenfeld
Journal:  World J Urol       Date:  1995       Impact factor: 4.226

2.  Preclinical and clinical studies with the multi-kinase inhibitor CEP-701 as treatment for prostate cancer demonstrate the inadequacy of PSA response as a primary endpoint.

Authors:  Connie Collins; Michael A Carducci; Mario A Eisenberger; John T Isaacs; Alan W Partin; Roberto Pili; Victoria J Sinibaldi; Janet S Walczak; Samuel R Denmeade
Journal:  Cancer Biol Ther       Date:  2007-06-05       Impact factor: 4.742
  2 in total

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