Literature DB >> 31818853

Genetic and Epigenetic Control of Heart Development.

Brynn N Akerberg1, William T Pu1,2.   

Abstract

A transcriptional program implemented by transcription factors and epigenetic regulators governs cardiac development and disease. Mutations in these factors are important causes of congenital heart disease. Here, we review selected recent advances in our understanding of the transcriptional and epigenetic control of heart development, including determinants of cardiac transcription factor chromatin occupancy, the gene regulatory network that regulates atrial septation, the chromatin landscape and cardiac gene regulation, and the role of Brg/Brahma-associated factor (BAF), nucleosome remodeling and histone deacetylation (NuRD), and Polycomb epigenetic regulatory complexes in heart development.
Copyright © 2020 Cold Spring Harbor Laboratory Press; all rights reserved.

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Year:  2020        PMID： 31818853      PMCID： PMC7280077          DOI： 10.1101/cshperspect.a036756

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Biol        ISSN： 1943-0264            Impact factor:   9.708


  79 in total

1.  The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism.

Authors:  Yan-Shan Dai; Peter Cserjesi; Bruce E Markham; Jeffery D Molkentin
Journal:  J Biol Chem       Date:  2002-05-06       Impact factor: 5.157

2.  Mature cardiomyocytes recall their progenitor experience via polycomb repressive complex 2.

Authors:  Aibin He; William T Pu
Journal:  Circ Res       Date:  2012-07-06       Impact factor: 17.367

3.  Morphogenesis of the right ventricle requires myocardial expression of Gata4.

Authors:  Elisabeth M Zeisberg; Qing Ma; Amy L Juraszek; Kelvin Moses; Robert J Schwartz; Seigo Izumo; William T Pu
Journal:  J Clin Invest       Date:  2005-05-12       Impact factor: 14.808

Review 4.  Decoding enhancers using massively parallel reporter assays.

Authors:  Fumitaka Inoue; Nadav Ahituv
Journal:  Genomics       Date:  2015-06-10       Impact factor: 5.736

5.  Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure.

Authors:  Egbert Bisping; Sadakatsu Ikeda; Sek Won Kong; Oleg Tarnavski; Natalya Bodyak; Julie R McMullen; Satish Rajagopal; Jennifer K Son; Qing Ma; Zhangli Springer; Peter M Kang; Seigo Izumo; William T Pu
Journal:  Proc Natl Acad Sci U S A       Date:  2006-09-18       Impact factor: 11.205

6.  Lack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation.

Authors:  Olga Ujhelly; Viktoria Szabo; Gergo Kovacs; Flora Vajda; Sylvia Mallok; Janos Prorok; Karoly Acsai; Zoltan Hegedus; Stefan Krebs; Andras Dinnyes; Melinda Katalin Pirity
Journal:  Stem Cells Dev       Date:  2015-06-25       Impact factor: 3.272

Review 7.  Structure and function insights into the NuRD chromatin remodeling complex.

Authors:  Morgan P Torchy; Ali Hamiche; Bruno P Klaholz
Journal:  Cell Mol Life Sci       Date:  2015-03-22       Impact factor: 9.261

8.  ChIP-seq accurately predicts tissue-specific activity of enhancers.

Authors:  Axel Visel; Matthew J Blow; Zirong Li; Tao Zhang; Jennifer A Akiyama; Amy Holt; Ingrid Plajzer-Frick; Malak Shoukry; Crystal Wright; Feng Chen; Veena Afzal; Bing Ren; Edward M Rubin; Len A Pennacchio
Journal:  Nature       Date:  2009-02-12       Impact factor: 49.962

9.  Large-scale discovery of enhancers from human heart tissue.

Authors:  Dalit May; Matthew J Blow; Tommy Kaplan; David J McCulley; Brian C Jensen; Jennifer A Akiyama; Amy Holt; Ingrid Plajzer-Frick; Malak Shoukry; Crystal Wright; Veena Afzal; Paul C Simpson; Edward M Rubin; Brian L Black; James Bristow; Len A Pennacchio; Axel Visel
Journal:  Nat Genet       Date:  2011-12-04       Impact factor: 38.330

10.  Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation.

Authors:  Andrew D Hoffmann; Xinan Holly Yang; Ozanna Burnicka-Turek; Joshua D Bosman; Xiaomeng Ren; Jeffrey D Steimle; Steven A Vokes; Andrew P McMahon; Vladimir V Kalinichenko; Ivan P Moskowitz
Journal:  PLoS Genet       Date:  2014-10-30       Impact factor: 5.917
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  3 in total

Review 1.  The control of polycomb repressive complexes by long noncoding RNAs.

Authors:  Jackson B Trotman; Keean C A Braceros; Rachel E Cherney; McKenzie M Murvin; J Mauro Calabrese
Journal:  Wiley Interdiscip Rev RNA       Date:  2021-04-16       Impact factor: 9.957

2.  RNA Biogenesis Instructs Functional Inter-Chromosomal Genome Architecture.

Authors:  Alessandro Bertero
Journal:  Front Genet       Date:  2021-03-01       Impact factor: 4.599

Review 3.  Molecular Genetics and Complex Inheritance of Congenital Heart Disease.

Authors:  Nicholas S Diab; Syndi Barish; Weilai Dong; Shujuan Zhao; Garrett Allington; Xiaobing Yu; Kristopher T Kahle; Martina Brueckner; Sheng Chih Jin
Journal:  Genes (Basel)       Date:  2021-06-30       Impact factor: 4.096
  3 in total

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