| Literature DB >> 31783859 |
Tahmid Kashem1, Fatima Al Sayah2, Andrews Tawiah3, Arto Ohinmaa2, Jeffery A Johnson2.
Abstract
OBJECTIVE: To examine the association between individual-level deprivation and health-related quality of life (HRQL) in the general population.Entities:
Keywords: CDI; Deprivation; EQ-5D-5 L; EuroQol; HRQL; ODI
Mesh:
Year: 2019 PMID: 31783859 PMCID: PMC6883516 DOI: 10.1186/s12955-019-1243-5
Source DB: PubMed Journal: Health Qual Life Outcomes ISSN: 1477-7525 Impact factor: 3.186
General characteristics of participants
| Characteristic | Overall ( |
|---|---|
| Age (Years) | |
| 18–44 | 2444 (38.7) |
| 45–64 | 2382 (37.7) |
| 65–75+ | 1421 (22.5) |
| Sex- female | 3809 (60.3) |
| Marital Status | |
| Married/Common-law | 4212 (66.7) |
| Widowed/Separated/ Divorced | 1057 (16.7) |
| Single, never married | 1006 (15.9) |
| Educational level | |
| High School not completed | 553 (8.8) |
| High School/Certificate | 3931 (62.3) |
| University | 1782 (28.2) |
| Employment status | |
| Employed | 3647 (62.8) |
| Out of work/Student | 703 (12.1) |
| Retired/Unable to work | 1455 (25.1) |
| Body Mass Index – kg/m2 | 27.52 ± 5.67 |
| Underweight: < 18.5 | 109 (1.8) |
| Normal: 18.5–25.0 | 2013 (33.2) |
| Overweight: 25.0–30.0 | 2242 (36.9) |
| Obese: > 30.0 | 1702 (28.1) |
| EQ-5D-5 L | |
| Mobility | |
| Level 1 | 4800 (76.0) |
| Levels 2–3 | 1315 (20.8) |
| Levels 4–5 | 199 (3.2) |
| Self-Care | |
| Level 1 | 5925 (93.8) |
| Levels 2–3 | 361 (5.7) |
| Levels 4–5 | 28 (0.4) |
| Usual Activities | |
| Level 1 | 4723 (74.8) |
| Levels 2–3 | 1422 (22.5) |
| Levels 4–5 | 169 (2.7) |
| Pain/Discomfort | |
| Level 1 | 2571 (40.7) |
| Levels 2–3 | 3408 (54.0) |
| Levels 4–5 | 335 (5.3) |
| Anxiety/Depression | |
| Level 1 | 4073 (64.5) |
| Levels 2–3 | 2089 (33.1) |
| Levels 4–5 | 152 (2.4) |
| Index Score | 0.85 ± 0.14 |
| VAS score | 79.6 ± 17.7 |
| Canadian Deprivation Index | |
| 1 (Most well-off) | 1401 (22.6) |
| 2 | 3117 (50.4) |
| 3 | 1175 (19.0) |
| 4 | 363 (5.7) |
| 5 (Least well-off) | 135 (2.2) |
| Ontario Deprivation Index (Range 0–10) | 0.17 ± 0.67 |
| Most well-off (0–1) | 5843 (96.1) |
| Least well-off (2–10) | 237 (3.9) |
EQ-5D-5 L dimensions, Index and VAS score across different deprivation indices reported as N (%) or mean ± SD
| EQ-5D-5 L | Canadian Deprivation Index (CDI) | Ontario Deprivation Index (ODI) | |||||
|---|---|---|---|---|---|---|---|
| 1 (Most Well off) ( | 2 ( | 3 ( | 4 ( | 5 (Least Well Off) ( | Score 0–1 ( | Score 2–10 ( | |
| Mobility | |||||||
| Level 1 | 1202 (85.8) | 2387 (76.6) | 830 (70.6) | 226 (62.3) | 74 (54.8) | 4553 (77.9) | 117 (49.4) |
| Levels 2–3 | 175 (12.5) | 666 (21.4) | 292 (24.8) | 106 (29.2) | 45 (33.3) | 1133 (19.5) | 94 (39.7) |
| Levels 4–5 | 24 (1.7) | 64 (2.0) | 53 (4.5) | 31 (8.5) | 16 (11.9) | 157 (2.6) | 26 (10.9) |
| Self-Care | |||||||
| Level 1 | 1363 (97.3) | 2948 (94.6) | 1081 (92.0) | 309 (85.1) | 115 (85.2) | 5539 (94.8) | 190 (80.2) |
| Levels 2–3 | 35 (2.5) | 160 (5.1) | 88 (7.5) | 50 (13.8) | 17 (12.6) | 284 (4.9) | 42 (17.7) |
| Levels 4–5 | 3 (0.2) | 9 (0.3) | 6 (0.5) | 4 (1.1) | 3 (2.2) | 20 (0.3) | 5 (2.1) |
| Usual Activities | |||||||
| Level 1 | 1159 (82.7) | 2351 (75.4) | 827 (70.4) | 232 (63.9) | 68 (50.4) | 4476 (76.6) | 100 (42.2) |
| Levels 2–3 | 223 (15.9) | 709 (22.8) | 309 (26.3) | 100 (27.6) | 54 (40.0) | 1245 (21.3) | 104 (43.8) |
| Levels 4–5 | 19 (1.4) | 57 (1.8) | 39 (3.3) | 31 (8.5) | 13 (9.6) | 122 (2.1) | 33 (14.0) |
| Pain/Discomfort | |||||||
| Level 1 | 703 (50.2) | 1249 (40.1) | 424 (36.1) | 113 (31.1) | 32 (23.7) | 2459 (42.1) | 37 (15.6) |
| Levels 2–3 | 662 (47.3) | 1737 (55.7) | 664 (56.5) | 201 (55.4) | 77 (57.0) | 3126 (53.5) | 149 (62.9) |
| Levels 4–5 | 36 (2.6) | 131 (4.2) | 87 (7.4) | 49 (13.5) | 26 (19.3) | 258 (4.4) | 51 (21.5) |
| Anxiety/Depression | |||||||
| Level 1 | 961 (68.6) | 2114 (67.8) | 699 (59.5) | 173 (47.7) | 46 (34.1) | 3855 (66.0) | 77 (32.5) |
| Levels 2–3 | 435 (31.1) | 954 (30.6) | 441 (37.5) | 154 (42.4) | 63 (46.7) | 1888 (32.3) | 119 (50.2) |
| Levels 4–5 | 5 (0.4) | 49 (1.6) | 35 (3.0) | 36 (9.9) | 26 (19.2) | 100 (1.7) | 41 (17.3) |
| Index Score | 0.88 ± 0.10 | 0.86 ± 0.12 | 0.83 ± 0.16 | 0.76 ± 0.22 | 0.71 ± 0.25 | 0.85 ± 0.13 | 0.68 ± 0.25 |
| VAS score | 83.1 ± 14.8 | 80.8 ± 16.3 | 77.1 ± 19.2 | 71.0 ± 23.2 | 64.7 ± 24.2 | 80.5 ± 16.9 | 66.0 ± 23.0 |
All differences were statistically significant (p < 0.001)
Results from multivariable logistic regression analysis of the association of CDI and ODI with EQ-5D-5 L dimensions, adjusted for age, sex, marital status and BMI
| Deprivation index | Mobility | Self-Care | Usual Activities | Pain/Discomfort | Anxiety/Depression |
|---|---|---|---|---|---|
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| CDI (1 Most well off) – reference | |||||
| 2 | 1.61 (1.34, 1.95) | 1.80 (1.25, 2.60) | 1.40 (1.18, 1.66) | 1.37 (1.19, 1.16) | 1.01 (0.88, 1.17) |
| 3 | 2.31 (1.86, 2.88) | 2.62 (1.75, 3.9) | 1.87 (1.53, 2.29) | 1.77 (1.49, 2.10) | 1.33 (1.12, 1.58) |
| 4 | 4.30 (3.20, 5.80) | 6.2 (3.92, 9.81) | 2.93 (2.21, 3.89) | 2.63 (2.01, 3.45) | 2.14 (1.67, 2.74) |
| 5 (Least well off) | 6.90 (4.53, 10.52) | 6.88 (3.77, 12.57) | 5.90 (3.95, 8.81) | 3.92 (2.53, 6.08) | 3.32 (2.25, 4.90) |
| ODI (Score 0–1) - reference | |||||
| Score 2–10 | 4.17 (3.10, 5.62) | 4.47 (3.10, 6.44) | 5.21 (3.90, 6.97) | 4.35 (2.97, 6.38) | 3.61 (2.69, 4.83) |
CDI Canadian Deprivation Index
ODI Ontario Deprivation Index
BMI Body Mass Index
All associations were statistically significant at p value < 0.05
Results from multivariable linear regression analysis of the association of CDI and ODI with EQ-5D-5 L index and VAS scores, adjusted for age, sex, marital status and BMI
| Deprivation index | Index Score | VAS Score | ||
|---|---|---|---|---|
| β (SE) | β (SE) | |||
| CDI (1 Most well off) – reference | ||||
| 2 | −0.02 (0.004) | < 0.01 | −1.6 (0.56) | < 0.01 |
| 3 | −0.05 (0.006) | < 0.01 | −5.1 (0.69) | < 0.01 |
| 4 | −0.12 (0.008) | < 0.01 | −11.4 (1.04) | < 0.01 |
| 5 (Least well off) | − 0.18 (0.01) | < 0.01 | −17.3 (1.57) | < 0.01 |
| ODI (Score 0–1) – reference | ||||
| Score 2–10 | −0.17 (0.01) | < 0.01 | −13.3 (1.15) | < 0.01 |
CDI Canadian Deprivation Index
ODI Ontario Deprivation Index
BMI Body Mass Index
VAS Visual Analogue Scale