Literature DB >> 3178383

Cancer treatment protocols. Who gets chosen?

J S Goodwin1, W C Hunt, C G Humble, C R Key, J M Samet.   

Abstract

We compared the age distribution of all adults in New Mexico with cancer incident from 1959 through 1982 with that of all adult New Mexican patients enrolled in cancer treatment protocols sponsored by the Southwest Oncology Group (New Mexico). For all cancer sites, elderly patients were substantially underrepresented in the Southwest Oncology Group protocols. While 31% of all adult patients with cancer were over age 70 years, only 7% of patients with cancer enrolled in Southwest Oncology Group protocols were in that age group. The underrepresentation of elderly individuals in cancer treatment protocols will make it difficult to determine optimal therapies for older patients with cancer.

Entities:  

Keywords:  Biomedical and Behavioral Research; Empirical Approach; Southwest Oncology Group

Mesh：

Year:  1988        PMID： 3178383

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN： 0003-9926


  13 in total

Review 1.  Comorbid disease and cancer: the need for more relevant conceptual models in health services research.

Authors:  Jane M Geraci; Carmen P Escalante; Jean L Freeman; James S Goodwin
Journal:  J Clin Oncol       Date:  2005-10-20       Impact factor: 44.544

Review 2.  Defining treatment aims and end-points in older patients with cancer.

Authors:  C E Desch; T J Smith
Journal:  Drugs Aging       Date:  1995-05       Impact factor: 3.923

3.  Population-based assessment of hospitalizations for toxicity from chemotherapy in older women with breast cancer.

Authors:  Xianglin L Du; Cynthia Osborne; James S Goodwin
Journal:  J Clin Oncol       Date:  2002-12-15       Impact factor: 44.544

4.  Outcomes following local therapy for early-stage breast cancer in non-trial populations.

Authors:  Nancy L Keating; Mary Beth Landrum; John M Brooks; Elizabeth A Chrischilles; Eric P Winer; Kara Wright; Rita Volya
Journal:  Breast Cancer Res Treat       Date:  2010-04-08       Impact factor: 4.872

5.  Cancer chemotherapy in the elderly: a series of 51 patients aged greater than 70 years.

Authors:  Y Bécouarn; B N Bui; R Brunet; A Ravaud
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

6.  Predictive capacity of three comorbidity indices in estimating mortality after surgery for colon cancer.

Authors:  Robert B Hines; Chakrapani Chatla; Harvey L Bumpers; John W Waterbor; Gerald McGwin; Ellen Funkhouser; Christopher S Coffey; James Posey; Upender Manne
Journal:  J Clin Oncol       Date:  2009-08-03       Impact factor: 44.544

7.  Temporal trends and predictors of perioperative chemotherapy use in elderly patients with resected nonsmall cell lung cancer.

Authors:  Jue Wang; Yong Fang Kuo; Jean Freeman; Avi B Markowitz; James S Goodwin
Journal:  Cancer       Date:  2008-01-15       Impact factor: 6.860

8.  Discrepancy between consensus recommendations and actual community use of adjuvant chemotherapy in women with breast cancer.

Authors:  Xianglin L Du; Charles R Key; Cynthia Osborne; Jonathan D Mahnken; James S Goodwin
Journal:  Ann Intern Med       Date:  2003-01-21       Impact factor: 25.391

9.  Toward optimal screening strategies for older women. Costs, benefits, and harms of breast cancer screening by age, biology, and health status.

Authors:  Jeanne S Mandelblatt; Clyde B Schechter; K Robin Yabroff; William Lawrence; James Dignam; Martine Extermann; Sarah Fox; Gretchen Orosz; Rebecca Silliman; Jennifer Cullen; Lodovico Balducci
Journal:  J Gen Intern Med       Date:  2005-06       Impact factor: 5.128

Review 10.  Epidemiology of breast cancer in older women: implications for future healthcare.

Authors:  A J Alberg; S Singh
Journal:  Drugs Aging       Date:  2001       Impact factor: 4.271
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