Talia Jarema1, Trent Aland2. 1. Icon Cancer Centres, Brisbane, Australia. Electronic address: Talia.Jarema@icon.team. 2. Icon Cancer Centres, Brisbane, Australia.
Abstract
PURPOSE: The ability to utilise a linear accelerators kV cone beam CT, for treatment planning and dosimetry calculation, has a number of potential uses including adaptive planning and daily dose analysis. This work validates the use of the iterative reconstruction of the Varian Halcyon cone beam CT (iCBCT) as datasets for radiation therapy planning of pelvis patients. METHODS: A CT to electron density (ED) curve was created in the Varian Eclipse treatment planning system (TPS) using scans of a CIRS ED phantom under a variety of scattering conditions. A pelvis phantom was imaged using a diagnostic CT scanner and Halcyon iCBCT. Ten pelvis patient plans were copied onto each dataset and compared using a global 3D gamma analysis. Each patient being treated on Halcyon has a daily iCBCT, and each plan was also recalculated on their respective day 1 iCBCT dataset. RESULTS: 3D Gamma analysis results for the patients planned on the pelvis phantom were analysed using a 1%/1mm and 2%/2mm, 10% low dose threshold criteria. The average pass rate was 99.4% ± 0.2%. The same metrics were used to analyse the patient plans recalculated on day 1 iCBCTs. The average result for the 1%/1mm gamma analysis was 94.4% ± 6.1%, and 98.6% ± 2.0% for 2%/2mm. A comparison of typical patient volumes showed average mean dose volume differences of 0.0% ± 1.4%, 0.0% ± 0.9% and 1.0% ± 4.0% for the PTV, Bladder and Rectum volumes respectively. CONCLUSIONS: Halcyon iCBCT datasets can be used for dose calculation in radiation therapy treatment planning for pelvis patients.
PURPOSE: The ability to utilise a linear accelerators kV cone beam CT, for treatment planning and dosimetry calculation, has a number of potential uses including adaptive planning and daily dose analysis. This work validates the use of the iterative reconstruction of the Varian Halcyon cone beam CT (iCBCT) as datasets for radiation therapy planning of pelvispatients. METHODS: A CT to electron density (ED) curve was created in the Varian Eclipse treatment planning system (TPS) using scans of a CIRS ED phantom under a variety of scattering conditions. A pelvis phantom was imaged using a diagnostic CT scanner and Halcyon iCBCT. Ten pelvispatient plans were copied onto each dataset and compared using a global 3D gamma analysis. Each patient being treated on Halcyon has a daily iCBCT, and each plan was also recalculated on their respective day 1 iCBCT dataset. RESULTS: 3D Gamma analysis results for the patients planned on the pelvis phantom were analysed using a 1%/1mm and 2%/2mm, 10% low dose threshold criteria. The average pass rate was 99.4% ± 0.2%. The same metrics were used to analyse the patient plans recalculated on day 1 iCBCTs. The average result for the 1%/1mm gamma analysis was 94.4% ± 6.1%, and 98.6% ± 2.0% for 2%/2mm. A comparison of typical patient volumes showed average mean dose volume differences of 0.0% ± 1.4%, 0.0% ± 0.9% and 1.0% ± 4.0% for the PTV, Bladder and Rectum volumes respectively. CONCLUSIONS: Halcyon iCBCT datasets can be used for dose calculation in radiation therapy treatment planning for pelvispatients.
Authors: Sadegh R Alam; Pengpeng Zhang; Si-Yuan Zhang; Ishita Chen; Andreas Rimner; Neelam Tyagi; Yu-Chi Hu; Wei Lu; Ellen D Yorke; Joseph O Deasy; Maria Thor Journal: Int J Radiat Oncol Biol Phys Date: 2021-01-13 Impact factor: 8.013
Authors: Damodar Pokhrel; Tanner Tackett; Joseph Stephen; Justin Visak; Falguni Amin-Zimmerman; Andrew McGregor; Stephen E Strup; William St Clair Journal: J Appl Clin Med Phys Date: 2020-12-19 Impact factor: 2.102
Authors: Damodar Pokhrel; Justin Visak; Lana C Critchfield; Joseph Stephen; Mark E Bernard; Marcus Randall; Mahesh Kudrimoti Journal: J Appl Clin Med Phys Date: 2020-12-20 Impact factor: 2.102
Authors: Damodar Pokhrel; Aaron Webster; Richard Mallory; Justin Visak; Mark E Bernard; Ronald C McGarry; Mahesh Kudrimoti Journal: J Appl Clin Med Phys Date: 2022-02-07 Impact factor: 2.243
Authors: Vincent Grégoire; Matthias Guckenberger; Karin Haustermans; Jan J W Lagendijk; Cynthia Ménard; Richard Pötter; Ben J Slotman; Kari Tanderup; Daniela Thorwarth; Marcel van Herk; Daniel Zips Journal: Mol Oncol Date: 2020-06-29 Impact factor: 6.603