Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Advancements to the Axolotl Model for Regeneration and Aging.

Literature DB >> 31779024

Advancements to the Axolotl Model for Regeneration and Aging.

Warren A Vieira¹, Kaylee M Wells¹, Catherine D McCusker².

Abstract

Loss of regenerative capacity is a normal part of aging. However, some organisms, such as the Mexican axolotl, retain striking regenerative capacity throughout their lives. Moreover, the development of age-related diseases is rare in this organism. In this review, we will explore how axolotls are used as a model system to study regenerative processes, the exciting new technological advancements now available for this model, and how we can apply the lessons we learn from studying regeneration in the axolotl to understand, and potentially treat, age-related decline in humans.

Entities: CellLine Chemical Disease Gene Species

Keywords: Aging; Axolotl; Cancer; Immune system; Nerve signaling; Regeneration; Scar formation; Technological advances

Mesh：

Year: 2019 PMID： 31779024 PMCID： PMC7214127 DOI： 10.1159/000504294

Source DB: PubMed Journal: Gerontology ISSN： 0304-324X Impact factor: 5.140

89 in total

1. THE NERVE AND THE EPIDERMAL APICAL CAP IN REGENERATION OF THE FORELIMB OF ADULT TRITURUS.

Authors: M SINGER; S INOUE
Journal: J Exp Zool Date: 1964-02

2. A stepwise model system for limb regeneration.

Authors: Tetsuya Endo; Susan V Bryant; David M Gardiner
Journal: Dev Biol Date: 2004-06-01 Impact factor: 3.582

3. GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.

Authors: Marc A Egerman; Samuel M Cadena; Jason A Gilbert; Angelika Meyer; Hallie N Nelson; Susanne E Swalley; Carolyn Mallozzi; Carsten Jacobi; Lori L Jennings; Ieuan Clay; Gaëlle Laurent; Shenglin Ma; Sophie Brachat; Estelle Lach-Trifilieff; Tea Shavlakadze; Anne-Ulrike Trendelenburg; Andrew S Brack; David J Glass
Journal: Cell Metab Date: 2015-05-19 Impact factor: 27.287

4. Signaling and Damaging Functions of Free Radicals in Aging-Free Radical Theory, Hormesis, and TOR.

Authors: Igor Afanas'ev
Journal: Aging Dis Date: 2010-07-12 Impact factor: 6.745

5. Responses of denervated adult newt limb stumps to reinnervation and reinjury.

Authors: J D Salley; R A Tassava
Journal: J Exp Zool Date: 1981-02

6. Cells keep a memory of their tissue origin during axolotl limb regeneration.

Authors: Martin Kragl; Dunja Knapp; Eugen Nacu; Shahryar Khattak; Malcolm Maden; Hans Henning Epperlein; Elly M Tanaka
Journal: Nature Date: 2009-07-02 Impact factor: 49.962

7. Fundamental differences in dedifferentiation and stem cell recruitment during skeletal muscle regeneration in two salamander species.

Authors: Tatiana Sandoval-Guzmán; Heng Wang; Shahryar Khattak; Maritta Schuez; Kathleen Roensch; Eugeniu Nacu; Akira Tazaki; Alberto Joven; Elly M Tanaka; András Simon
Journal: Cell Stem Cell Date: 2013-11-21 Impact factor: 24.633

8. Blastema cell proliferation in vitro: effects of limb amputation on the mitogenic activity of spinal cord extracts.

Authors: B Boilly; P Albert
Journal: Biol Cell Date: 1988 Impact factor: 4.458

9. Heart regeneration in the salamander relies on macrophage-mediated control of fibroblast activation and the extracellular landscape.

Authors: J W Godwin; R Debuque; E Salimova; N A Rosenthal
Journal: NPJ Regen Med Date: 2017-07-27

10. Foamy virus for efficient gene transfer in regeneration studies.

Authors: Shahryar Khattak; Tatiana Sandoval-Guzmán; Nicole Stanke; Stephanie Protze; Elly M Tanaka; Dirk Lindemann
Journal: BMC Dev Biol Date: 2013-05-03 Impact factor: 1.978

13 in total

Review 1. Revelations About Aging and Disease from Unconventional Vertebrate Model Organisms.

Authors: Yang Zhao; Andrei Seluanov; Vera Gorbunova
Journal: Annu Rev Genet Date: 2021-08-20 Impact factor: 16.830

2. Spatial transcriptomics reveals metabolic changes underly age-dependent declines in digit regeneration.

Authors: Robert J Tower; Emily Busse; Josue Jaramillo; Michelle Lacey; Kevin Hoffseth; Anyonya R Guntur; Jennifer Simkin; Mimi C Sammarco
Journal: Elife Date: 2022-05-26 Impact factor: 8.713

Review 3. Can neural signals override cellular decisions in the presence of DNA damage?

Authors: Salvador Rojas; Néstor J Oviedo
Journal: DNA Repair (Amst) Date: 2021-04-20

4. The amazing and anomalous axolotls as scientific models.

Authors: Carly J Adamson; Nikolas Morrison-Welch; Crystal D Rogers
Journal: Dev Dyn Date: 2022-04-01 Impact factor: 2.842

Review 5. The Role of the Microbiota in Regeneration-Associated Processes.

Authors: Lymarie M Díaz-Díaz; Andrea Rodríguez-Villafañe; José E García-Arrarás
Journal: Front Cell Dev Biol Date: 2022-01-26

6. Reawakening GDNF's regenerative past in mice and humans.

Authors: Andres Samos; Vanessa McGaughey; Sandra Rieger; Thomas S Lisse
Journal: Regen Ther Date: 2022-04-19 Impact factor: 3.651

7. Construction of the axolotl cell landscape using combinatorial hybridization sequencing at single-cell resolution.

Authors: Fang Ye; Guodong Zhang; Weigao E; Haide Chen; Chengxuan Yu; Lei Yang; Yuting Fu; Jiaqi Li; Sulei Fu; Zhongyi Sun; Lijiang Fei; Qile Guo; Jingjing Wang; Yanyu Xiao; Xinru Wang; Peijing Zhang; Lifeng Ma; Dapeng Ge; Suhong Xu; Juan Caballero-Pérez; Alfredo Cruz-Ramírez; Yincong Zhou; Ming Chen; Ji-Feng Fei; Xiaoping Han; Guoji Guo
Journal: Nat Commun Date: 2022-07-22 Impact factor: 17.694

Review 8. Alternative Animal Models of Aging Research.

Authors: Susanne Holtze; Ekaterina Gorshkova; Stan Braude; Alessandro Cellerino; Philip Dammann; Thomas B Hildebrandt; Andreas Hoeflich; Steve Hoffmann; Philipp Koch; Eva Terzibasi Tozzini; Maxim Skulachev; Vladimir P Skulachev; Arne Sahm
Journal: Front Mol Biosci Date: 2021-05-17

Review 9. Salamanders: The molecular basis of tissue regeneration and its relevance to human disease.

Authors: Claudia Marcela Arenas Gómez; Karen Echeverri
Journal: Curr Top Dev Biol Date: 2021-03-16 Impact factor: 4.897

10. Dissecting the Molecular Signature of Spinal Cord Regeneration in the Axolotl Model.

Authors: Turan Demircan
Journal: Cureus Date: 2020-02-16